Patents by Inventor Haiyan CHU

Haiyan CHU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric antigen receptor-expressing T cells as anti-cancer therapeutics
    Patent number: 12150981
    Abstract: Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.
    Type: Grant
    Filed: July 28, 2021
    Date of Patent: November 26, 2024
    Assignee: Purdue Research Foundation
    Inventors: Philip S. Low, Haiyan Chu, Yong Gu Lee
  • Methods and compositions for car T cell therapy
    Patent number: 12144850
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: November 19, 2024
    Assignees: Purdue Research Foundation, Endocyte, Inc
    Inventors: Philip Stewart Low, Haiyan Chu, Yong Gu Lee
  • COMPOSITIONS AND METHODS FOR CAR T CELL THERAPY
    Publication number: 20240165159
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: October 25, 2023
    Publication date: May 23, 2024
    Inventors: Philip Stewart LOW, Haiyan CHU, Yong Gu LEE, Yingjuan J. LU, Christopher Paul LEAMON, Leroy W. WHEELER, II
  • METHODS OF USE FOR CAR T CELLS
    Publication number: 20240075069
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 7, 2024
    Inventors: Philip Stewart LOW, Haiyan CHU, Yingjuan June LU, Christopher Paul LEAMON, Leroy W. WHEELER, II, Michael C. JENSEN, James MATTHAEI
  • Compositions and methods for CAR T cell therapy
    Patent number: 11850262
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: December 26, 2023
    Assignees: Purdue Research Foundation, Endocyte, Inc.
    Inventors: Philip Stewart Low, Haiyan Chu, Yong Gu Lee, Yingjuan J. Lu, Christopher Paul Leamon, Leroy W. Wheeler, II
  • Methods of use for CAR T cells
    Patent number: 11779602
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: October 10, 2023
    Assignees: Endocyte, Inc., Purdue Research Foundation, Seattle Children's Hospital
    Inventors: Philip Stewart Low, Haiyan Chu, Yingjuan June Lu, Christopher Paul Leamon, Leroy W. Wheeler, II, Michael C. Jensen, James Matthaei
  • Compositions and methods for CAR T cell therapy
    Patent number: 11759480
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: July 6, 2020
    Date of Patent: September 19, 2023
    Assignees: ENDOCYTE, INC., PURDUE RESEARCH FOUNDATION
    Inventors: Philip Stewart Low, Haiyan Chu, Yong Gu Lee, Yingjuan J. Lu, Christopher Paul Leamon, Leroy W Wheeler, II
  • CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS
    Publication number: 20220000996
    Abstract: Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.
    Type: Application
    Filed: July 28, 2021
    Publication date: January 6, 2022
    Inventors: Philip S. LOW, Haiyan CHU, Yong Gu LEE
  • SEQUENCING METHOD FOR CAR T CELL THERAPY
    Publication number: 20210346431
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: February 22, 2019
    Publication date: November 11, 2021
    Inventors: Richard MESSMANN, Christopher Paul LEAMON, Haiyan CHU, Yingjuan June LU, Philip Stewart LOW, Michael C. JENSEN, James MATTHAEI, Navin Robert Charles PINTO, Julie Ruggieri PARK
  • COMPOSITIONS AND METHODS FOR CAR T CELL THERAPY
    Publication number: 20200405760
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: July 6, 2020
    Publication date: December 31, 2020
    Inventors: Philip Stewart LOW, Haiyan CHU, Yong Gu LEE, Yingjuan J. LU, Christopher Paul LEAMON, Leroy W WHEELER
  • COMPOSITIONS AND METHODS FOR CAR T CELL THERAPY
    Publication number: 20200023009
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: February 28, 2018
    Publication date: January 23, 2020
    Inventors: Philip Stewart LOW, Haiyan CHU, Yong Gu LEE, Yingjuan J. LU, Christopher Paul LEAMON, Leroy W. WHEELER, II
  • METHODS OF USE FOR CAR T CELLS
    Publication number: 20190255109
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: January 22, 2019
    Publication date: August 22, 2019
    Inventors: Philip Stewart LOW, Haiyan CHU, Yingjuan June LU, Christopher Paul LEAMON, Leroy W. WHEELER, II, Michael C. JENSEN, James MATTHAEI
  • METHODS AND COMPOSITIONS FOR CAR T CELL THERAPY
    Publication number: 20190091308
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Application
    Filed: April 7, 2017
    Publication date: March 28, 2019
    Inventors: Philip Stewart LOW, Haiyan CHU, Yong Gu LEE
  • CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS
    Publication number: 20170290900
    Abstract: Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.
    Type: Application
    Filed: October 18, 2016
    Publication date: October 12, 2017
    Inventors: Philip S. Low, Haiyan Chu, Yong Gu Lee
  • CHIMERIC ANTIGEN RECEPTOR-EXPRESSING T CELLS AS ANTI-CANCER THERAPEUTICS
    Publication number: 20150320799
    Abstract: Cytotoxic lymphocytes expressing chimeric antigen receptors (CAR) that target and bind small conjugate molecules (SCM) are disclosed, as well as methods of using the cells and the SCMs in the treatment of cancer.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 12, 2015
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Philip LOW, Haiyan CHU, Yong Gu LEE