Patents by Inventor Haizhen Zhang

Haizhen Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230028221
    Abstract: The present invention relates to a compound of formula (X) or a tautomer, stereoisomer, prodrug, crystal form, pharmaceutically acceptable salt, hydrate or solvate thereof, and a pharmaceutical composition containing the compound and a use.
    Type: Application
    Filed: November 2, 2020
    Publication date: January 26, 2023
    Inventors: Wei Qi, Haizhen Zhang, Xin Ma, Hui Lei, Yuhua George Zhang, Yuxiu Qu
  • Patent number: 11492365
    Abstract: This disclosure relates to GLP-1 agonists of Formula (I): including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.
    Type: Grant
    Filed: January 7, 2022
    Date of Patent: November 8, 2022
    Assignee: GASHERBRUM BIO, INC.
    Inventors: Qinghua Meng, Xichen Lin, Haizhen Zhang, Hui Lei, Andrew Jennings
  • Publication number: 20220284022
    Abstract: Systems and methods are provided for receiving an input comprising one or more attributes, selecting a subset of query options from a list of query options relevant to the attributes of the input, and based on query optimization results from an audit of previous queries, determining a priority order to execute each query in the set of queries based on the query optimization results, and executing each query in the priority order to generate a candidate list. For each candidate in the list of candidates, systems and methods are provided for selecting a subset of available workflows based on relevance to the candidate and based on workflow optimization results, determining an order in which the selected subset of workflows is to be executed, and executing the selected subset of workflows in the determined order to generate a match score indicating the probability that the candidate matches the input.
    Type: Application
    Filed: May 24, 2022
    Publication date: September 8, 2022
    Inventors: Quincy Milton, Henry Tsai, Uma Kale, Adam Horacek, Justin Dority, Phillip DuLion, Ian Kelley, Michael Lentz, Ryan Skorupski, Aditi Godbole, Haizhen Zhang
  • Publication number: 20220213130
    Abstract: This disclosure relates to GLP-1 agonists of Formula (I): including pharmaceutically acceptable salts and solvates thereof, and pharmaceutical compositions including the same.
    Type: Application
    Filed: January 7, 2022
    Publication date: July 7, 2022
    Inventors: Qinghua Meng, Xichen Lin, Haizhen Zhang, Weiqiang Xing, Hui Lei, Andrew Jennings
  • Patent number: 11372857
    Abstract: Systems and methods are provided for receiving an input comprising one or more attributes, selecting a subset of query options from a list of query options relevant to the attributes of the input, and based on query optimization results from an audit of previous queries, determining a priority order to execute each query in the set of queries based on the query optimization results, and executing each query in the priority order to generate a candidate list. For each candidate in the list of candidates, systems and methods are provided for selecting a subset of available workflows based on relevance to the candidate and based on workflow optimization results, determining an order in which the selected subset of workflows is to be executed, and executing the selected subset of workflows in the determined order to generate a match score indicating the probability that the candidate matches the input.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: June 28, 2022
    Assignee: SAP SE
    Inventors: Quincy Milton, Henry Tsai, Uma Kale, Adam Horacek, Justin Dority, Phillip DuLion, Ian Kelley, Michael Lentz, Ryan Skorupski, Aditi Godbole, Haizhen Zhang
  • Publication number: 20220138198
    Abstract: Systems and methods are provided for receiving an input comprising one or more attributes, selecting a subset of query options from a list of query options relevant to the attributes of the input, and based on query optimization results from an audit of previous queries, determining a priority order to execute each query in the set of queries based on the query optimization results, and executing each query in the priority order to generate a candidate list. For each candidate in the list of candidates, systems and methods are provided for selecting a subset of available workflows based on relevance to the candidate and based on workflow optimization results, determining an order in which the selected subset of workflows is to be executed, and executing the selected subset of workflows in the determined order to generate a match score indicating the probability that the candidate matches the input.
    Type: Application
    Filed: October 29, 2020
    Publication date: May 5, 2022
    Inventors: Quincy Milton, Henry Tsai, Uma Kale, Adam Horacek, Justin Dority, Phillip DuLion, Ian Kelley, Michael Lentz, Ryan Skorupski, Aditi Godbole, Haizhen Zhang
  • Patent number: 11214562
    Abstract: A compound of the Formula (1) is below provided where R1-R5 are as described in the description and each “*” represents a chiral center.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: January 4, 2022
    Assignee: ELI LILLY AND COMPANY
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Zeng, Haizhen Zhang
  • Publication number: 20210292302
    Abstract: A compound of the Formula (1) is below provided where R1-R5 are as described in the description and each “*” represents a chiral center.
    Type: Application
    Filed: July 17, 2017
    Publication date: September 23, 2021
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Mi Zeng, Haizhen Zhang
  • Patent number: 11117891
    Abstract: The present invention provides a compound of Formula II wherein X is selected from the group consisting of CH and N; Q is selected from the group consisting of CH3 and H; R is selected from the group consisting of and; or a pharmaceutically acceptable salt thereof, compositions, methods to treat liver disease and NASH.
    Type: Grant
    Filed: February 21, 2018
    Date of Patent: September 14, 2021
    Assignee: Eli Lilly and Company
    Inventors: Hui Lei, Gang Liu, Yuan Tian, Haizhen Zhang
  • Publication number: 20200062751
    Abstract: The present invention provides a compound of Formula I I wherein X is selected from the group consisting of CH and N; Q is selected from the group consisting of CH3 and H; R is selected from the group consisting of and; or a pharmaceutically acceptable salt thereof, compositions, methods to treat liver disease and NASH.
    Type: Application
    Filed: February 21, 2018
    Publication date: February 27, 2020
    Inventors: Hui LEI, Gang LIU, Yuan TIAN, Haizhen ZHANG
  • Patent number: 10370352
    Abstract: The present invention provides a compound of Formula I wherein Q is selected from the group consisting of —CH(CH3)2 and R is selected from the group consisting of or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: August 6, 2019
    Assignee: ELI LILLY AND COMPANY
    Inventors: Lian Zhu Liu, Haizhen Zhang, Xiaoqing Wang, Gang Liu
  • Publication number: 20190071413
    Abstract: The present invention provides a compound of Formula I wherein Q is selected from the group consisting of —CH(CH3)2 and R is selected from the group consisting of or a pharmaceutically acceptable salt thereof; compositions, methods to treat liver disease and NASH.
    Type: Application
    Filed: September 6, 2018
    Publication date: March 7, 2019
    Inventors: Lian Zhu LIU, Haizhen ZHANG, Xiaoqing WANG, Gang LIU
  • Patent number: 10196385
    Abstract: The present invention provides compounds of the Formula below wherein R, R1-R3 are as described herein; methods of treating patients for diabetes using the compounds, and processes for preparing the compounds.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 5, 2019
    Assignee: Eli Lilly and Company
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Haizhen Zhang, Jingye Zhou
  • Publication number: 20180194755
    Abstract: The present invention provides compounds of the Formula below wherein R, R1-R3 are as described herein; methods of treating patients for diabetes using the compounds, and processes for preparing the compounds
    Type: Application
    Filed: February 19, 2016
    Publication date: July 12, 2018
    Inventors: Zhi Long Hu, Lian Zhu Liu, Tianwei Ma, Haizhen Zhang, Jingye Zhou