Abstract: Disclosed is a crack detection apparatus for detecting a building structure, belonging to the technical field of building detection and including a main shaft collar, an auxiliary shaft collar, a rotating drum, a bracket assembly, a crawling mechanism and a transmission assembly, where the main shaft collar is rotationally connected with the auxiliary shaft collar, main slewing arms and auxiliary slewing arms that are in X-shaped crossing are arranged on the main shaft collar and the auxiliary shaft collar, the rotating drum swinging back and forth is rotationally assembled on the main shaft collar, a tail end of the rotating drum is provided with a cleaning arm, the crawling mechanism is assembled at tail ends of the main slewing arms and the auxiliary slewing arms and connected with the rotating drum through the transmission assembly.

Abstract: The present invention provides aqueous in-situ gel ophthalmic formulations, each including water, difluprednate and a biocompatible polysaccharide, wherein a gel is formed in situ at physiological temperature with instant viscosity increase upon instillation of the formulation into an eye. In the formulations, nanocarriers may be formed by a surfactant or solubilizer contained in the formulation, with or encapsulating difluprednate, and the nanocarriers have an average particle size of 10 to 500 nm or 10 to 150 nm or 10- to 50 nm.

Abstract: The present invention provides aqueous ophthalmic formulations containing 0.01%-5% by weight of cyclosporine which exists in the form of micelles having a particle size not greater than 20 nm, and methods of making and using such formulations.