Patents by Inventor Hajime Ishida
Hajime Ishida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10098866Abstract: A stabilized preparation which comprises: a unstable drug in a polyethylene glycol-containing preparation; and a coating agent comprising a copolyvidone instead of polyethylene glycol with which the drug is coated.Type: GrantFiled: August 11, 2016Date of Patent: October 16, 2018Assignee: Takeda Pharmaceutical Company LimitedInventors: Hajime Ishida, Makoto Fukuta
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Publication number: 20170020841Abstract: A stabilized preparation which comprises: a unstable drug in a polyethylene glycol-containing preparation; and a coating agent comprising a copolyvidone instead of polyethylene glycol with which the drug is coated.Type: ApplicationFiled: August 11, 2016Publication date: January 26, 2017Inventors: Hajime Ishida, Makoto Fukuta
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Patent number: 8828429Abstract: The present invention relates to a controlled release capsule preparation for oral administration, which contains (i) a granule containing a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring optionally having substituent(s), or a salt thereof, and a hydrophilic polymer, and coated with an enteric coating agent and the like, and (ii) a fluidizer. According to the present invention, a controlled release composition for oral administration of an imidazole derivative, which has steroid C17,20-lyase inhibiting activity and which has remarkably improved sustainability of the blood concentration, is provided.Type: GrantFiled: March 3, 2006Date of Patent: September 9, 2014Assignee: Takeda Pharmaceutical Company LimitedInventors: Hajime Ishida, Yukihiro Nomura
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Patent number: 8740287Abstract: Disclosed is a passenger protection device (12) for a vehicle, which protects a passenger (Mn) sitting on a seat (11) when an external force (Fs) is applied to a side surface (16a) of a vehicle body (16). The passenger protection device has a side support (14). The side support is provided on the side portion of a seat back (46), and supports the upper body (Bu) of the passenger. The side support has a deformable portion (47). The deformable portion allows the side support to be deformed by an external force having a predetermined value or more.Type: GrantFiled: April 20, 2010Date of Patent: June 3, 2014Assignee: Honda Motor Co., Ltd.Inventors: Kazuhiro Onda, Nobuhiro Kawamoto, Itaru Genpei, Makoto Uchikawa, Takashi Kikuchi, Hajime Ishida
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Patent number: 8624062Abstract: A method for producing a phenylacetamide compound represented by formula (1): wherein Q represents a hydrogen atom or a halogen atom, R2 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R4 represents an alkyl group having 1 to 4 carbon atoms, Ar represents an unsubstituted or substituted phenyl group, R5 represents R4 when R2 is a hydrogen atom, and R5 represents a hydrogen atom when R2 is an alkyl group having 1 to 4 carbon atoms; including reacting a phenylacetamide compound represented by formula (2): wherein Q, R2 and Ar have the same meanings as defined above; with a dialkyl sulfate represented by formula (3): wherein R4 has the same meaning as defined above; in the presence of a base.Type: GrantFiled: February 12, 2010Date of Patent: January 7, 2014Assignee: Sumitomo Chemical Company, LimitedInventors: Hajime Ishida, Masaji Hirota, Yoko Miyanaga, Yuya Mizushima
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Patent number: 8309752Abstract: A method for producing a compound represented by the following formula (2) (wherein, X, R1 and m represent respectively the same meaning as described below) which comprises reacting a compound represented by the following formula (1) (wherein, X represents an optionally substituted alkyl group or the like. R1 represents an optionally substituted alkyl group or the like. m represents an integer of 0 to 4. When m represents an integer of 2 to 4, R1s may be the same or different from each other) with hydrogen cyanide in an amount of 1.2 to 5 mol with respect to 1 mol of the compound, in the presence of an organic base, in an organic solvent.Type: GrantFiled: June 24, 2009Date of Patent: November 13, 2012Assignee: Sumitomo Chemical Company, LimitedInventors: Hajime Ishida, Masaji Hirota
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Patent number: 8299288Abstract: Disclosed is a method for producing a compound represented by Formula (4), the method including Step I of adding a solution in which hydrogen chloride is dissolved in an alcohol, to a mixture containing an organic solvent and a compound represented by Formula (1), and Step II of mixing a compound obtained in Step I, represented by Formula (3), with water.Type: GrantFiled: August 24, 2009Date of Patent: October 30, 2012Assignee: Sumitomo Chemical Company, LimitedInventors: Hajime Ishida, Masaji Hirota
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Publication number: 20120267882Abstract: The embodiments herein describe a fundamental layout between the inner panel of a door, side sill reinforcement, and uncrushable items within the door of the vehicle. During a side impact collision, a side impact sensor receives a G-signal resulting from the collision. The G-signal must ramp up to a threshold value in order to deploy the side airbag. The fundamental layout between the inner panel of a door, side sill reinforcement, and uncrushable items within the door of the vehicle ensures a more robust G-signal which results in early deployment of the side airbag relative to the movement of the door toward the occupant.Type: ApplicationFiled: April 19, 2011Publication date: October 25, 2012Applicant: HONDA MOTOR CO., LTD.Inventors: Lando Crispin Hamlett, Hajime Ishida, Siyang Yang
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Publication number: 20120038182Abstract: Disclosed is a passenger protection device (12) for a vehicle, which protects a passenger (Mn) sitting on a seat (11) when an external force (Fs) is applied to a side surface (16a) of a vehicle body (16). The passenger protection device has a side support (14). The side support is provided on the side portion of a seat back (46), and supports the upper body (Bu) of the passenger. The side support has a deformable portion (47). The deformable portion allows the side support to be deformed by an external force having a predetermined value or more.Type: ApplicationFiled: April 20, 2010Publication date: February 16, 2012Applicant: HONDA MOTOR CO., LTD.Inventors: Kazuhiro Onda, Nobuhiro Kawamoto, Itaru Genpei, Makoto Uchikawa, Takashi Kikuchi, Hajime Ishida
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Publication number: 20110295035Abstract: A method for producing a phenylacetamide compound represented by formula (1): wherein Q represents a hydrogen atom or a halogen atom, R2 represents a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, R4 represents an alkyl group having 1 to 4 carbon atoms, Ar represents an unsubstituted or substituted phenyl group, R5 represents R4 when R2 is a hydrogen atom, and R5 represents a hydrogen atom when R2 is an alkyl group having 1 to 4 carbon atoms; including reacting a phenylacetamide compound represented by formula (2): wherein Q, R2 and Ar have the same meanings as defined above; with a dialkyl sulfate represented by formula (3): wherein R4 has the same meaning as defined above; in the presence of a base.Type: ApplicationFiled: February 12, 2010Publication date: December 1, 2011Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Hajime Ishida, Masaji Hirota, Yoko Miyanaga, Yuya Mizushima
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Publication number: 20110144372Abstract: Disclosed is a method for producing a compound represented by Formula (4), the method including Step I of adding a solution in which hydrogen chloride is dissolved in an alcohol, to a mixture containing an organic solvent and a compound represented by Formula (1), and Step II of mixing a compound obtained in Step I, represented by Formula (3), with water.Type: ApplicationFiled: August 24, 2009Publication date: June 16, 2011Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Hajime Ishida, Massaji Hirota
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Publication number: 20110118498Abstract: A method for producing a compound represented by the following formula (2) (wherein, X, R1 and m represent respectively the same meaning as described below) which comprises reacting a compound represented by the following formula (1) (wherein, X represents an optionally substituted alkyl group or the like. R1 represents an optionally substituted alkyl group or the like. m represents an integer of 0 to 4. When m represents an integer of 2 to 4, R1s may be the same or different from each other) with hydrogen cyanide in an amount of 1.2 to 5 mol with respect to 1 mol of the compound, in the presence of an organic base, in an organic solvent.Type: ApplicationFiled: June 24, 2009Publication date: May 19, 2011Inventors: Hajime Ishida, Masaji Hirota
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Patent number: 7709685Abstract: An object of the present invention is to provide a method capable of producing cycloalkanol and/or cycloalkanone with a favorable selectivity by oxidizing cycloalkane with a favorable conversion. A cycloalkanol and/or cycloalkanone are produced by oxidizing cycloalkane with oxygen in the presence of mesoporous silica which contains at least one metal selected from metals of Groups 5 to 10 of the Periodic Table and which is also subjected to a contact treatment with an organosilicon compound. The metal is preferably at least one metal selected from the group consisting of vanadium, chromium, manganese, iron, cobalt, ruthenium and palladium, and the mesoporous silica is preferably MCM-41 type mesoporous silica.Type: GrantFiled: March 14, 2008Date of Patent: May 4, 2010Assignee: Sumitomo Chemical Company, LimitedInventors: Masahiro Hoshino, Tatsuya Suzuki, Hajime Ishida
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Patent number: 7632942Abstract: The object of the present invention is to produce cycloalkanol and/or cycloalkanone with good selectivity by oxidizing cycloalkane with molecular oxygen. The method of the present invention contains the step of oxidizing cycloalkane with molecular oxygen in the presence of cobalt salt of carboxylic acid and cobalt complex with porphyrin as a ligand, the cobalt complex with porphyrin as a ligand being a compound represented by the formula (1): wherein each of X1 to X8 independently represents a hydrogen atom, a halogen atom, a nitro group, a cyano group, a hydrocarbon group, a halogenated hydrocarbon group or a sulfonyl group, and each of R1 to R4 independently represents a hydrogen atom, a nitro group, a cyano group, a hydrocarbon group or a halogenated hydrocarbon group.Type: GrantFiled: July 19, 2005Date of Patent: December 15, 2009Assignee: Sumitomo Chemical Company, LimitedInventor: Hajime Ishida
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Patent number: 7622615Abstract: There is provided a process with which the cycloalkane is oxidized so as to produce a cycloalkanol and/or a cycloalkanone with an improved conversion of the cycloalkane. Such process includes the steps of supplying the oxygen-containing gas and a liquid including the cycloalkane into a bubble forming apparatus so as to prepare a gas-liquid mixture, and supplying such gas-liquid mixture into a reaction vessel.Type: GrantFiled: April 10, 2008Date of Patent: November 24, 2009Assignee: Sumitomo Chemical Company, LimitedInventors: Hajime Ishida, Masashi Yokota
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Publication number: 20090274733Abstract: A stabilized preparation which comprises: a unstable drug in a polyethylene glycol-containing preparation; and a coating agent comprising a copolyvidone instead of polyethylene glycol with which the drug is coated.Type: ApplicationFiled: July 1, 2009Publication date: November 5, 2009Applicant: Takeda Pharmaceutical Company, LtdInventors: Hajime Ishida, Makoto Fukuta
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Publication number: 20090053308Abstract: The present invention relates to a controlled release capsule preparation for oral administration, which contains (i) a granule containing a physiologically active substance which is a compound represented by the formula: wherein n is an integer of 1 to 3, and Ar is an aromatic ring optionally having substituent(s), or a salt thereof, and a hydrophilic polymer, and coated with an enteric coating agent and the like, and (ii) a fluidizer. According to the present invention, a controlled release composition for oral administration of an imidazole derivative, which has steroid C17,20-lyase inhibiting activity and which has remarkably improved sustainability of the blood concentration, is provided.Type: ApplicationFiled: March 3, 2006Publication date: February 26, 2009Applicant: Takeda Pharmaceutical Company LimitedInventors: Hajime Ishida, Yukihiro Nomura
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Publication number: 20080255392Abstract: There is provided a process with which the cycloalkane is oxidized so as to produce a cycloalkanol and/or a cycloalkanone with an improved conversion of the cycloalkane. Such process includes the steps of supplying the oxygen-containing gas and a liquid including the cycloalkane into a bubble forming apparatus so as to prepare a gas-liquid mixture, and supplying such gas-liquid mixture into a reaction vessel.Type: ApplicationFiled: April 10, 2008Publication date: October 16, 2008Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Hajime Ishida, Masashi Yokota
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Publication number: 20080228007Abstract: An object of the present invention is to provide a method capable of producing cycloalkanol and/or cycloalkanone with a favorable selectivity by oxidizing cycloalkane with a favorable conversion. A cycloalkanol and/or cycloalkanone are produced by oxidizing cycloalkane with oxygen in the presence of mesoporous silica which contains at least one metal selected from metals of Groups 5 to 10 of the Periodic Table and which is also subjected to a contact treatment with an organosilicon compound. The metal is preferably at least one metal selected from the group consisting of vanadium, chromium, manganese, iron, cobalt, ruthenium and palladium, and the mesoporous silica is preferably MCM-41 type mesoporous silica.Type: ApplicationFiled: March 14, 2008Publication date: September 18, 2008Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Masahiro HOSHINO, Tatsuya Suzuki, Hajime Ishida
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Publication number: 20080076946Abstract: The object of the present invention is to provide a process capable of producing cycloalkanol and/or cycloalkanone in excellent selectivity by oxidizing cycloalkane in a good degree of conversion. The present invention relates to a process for producing cycloalkanol and/or cycloalkanone, which comprises oxidizing cycloalkane with oxygen at 25 to 140° C. in the presence of mesoporous silica containing the group 8 and/or 9 element in the periodic table, wherein the content of phosphorus atom in the mesoporous silica is 0 to 4 mol % based on silicon atom. Said element is preferably cobalt and said mesoporous silica is preferably MCM-41.Type: ApplicationFiled: September 6, 2007Publication date: March 27, 2008Applicant: SUMITOMO CHEMICAL COMPANY, LIMITEDInventors: Masahiro HOSHINO, Hajime Ishida, Tatsuya Suzuki