Abstract: An object of the present invention is to provide a vasopressin antagonist and oxytocin antagonist.The vasopressing antagonist and oxytocin antagonist according to the present invention contain, as the active ingredient, a benzoheterocyclic compound represented by the general formula (1): ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and the carbon-carbon bond between 4- and 5-positions in the benzoazepine skeleton are the same as defined in claims 1, 2 and 3.) or salt thereof.

Abstract: Novel benzoheterocyclic compounds of the formula: ##STR1## wherein R.sup.1 is H, halogen, alkyl, optionally substituted amino, alkoxy; R.sup.2 is H, halogen, alkoxy, phenyialkoxy, OH, alkyl, optionally substituted amino, carbamoyl-alkoxy, optionally substituted amino-alkoxy, optionally substituted benzoyloxy; R.sup.3 is a group: --NR.sup.4 R.sup.5 or --CO--NR.sup.11 R.sup.12 ; R.sup.4 is H, optionally substituted benzoyl, alkyl; R.sup.5 is a group: ##STR2## [R.sup.16 is halogen, optionally substituted alkyl, OH, alkoxy, alkanoyloxy, alkylthio, alkanoyl, carboxy, alkoxycarbonyl, CN, NO.sub.2, optionally substituted amino, phenyl, cycloalkyl, etc., or a group: --O--A--NR.sup.6 R.sup.7 ; m is 0 to 3], phenyl-alkoxycarbonyl, alkanoyl, phenylalkanoyl, etc.; R.sup.11 is H or alkyl; R.sup.12 is cycloalkyl or optionally substituted phenyl; and W is a group: --(CH.sub.2).sub.p (p is 3 to 5) or --CH.dbd.CH--(CH.sub.2).sub.q (q is 1 to 3), the carbon atom of these groups being optionally replaced by O, S, SO, SO.sub.

Abstract: Novel carbostyril derivatives of the formula: ##STR1## wherein X is 0 or S; Y is H or alkyl; R.sup.A is a group of the ##STR2## {wherein n is 1 or 2, A is alkylene, R.sup.1 is benzoyl having optionally 1-3 substituents, R.sup.2A is ##STR3## is (i) alkoxy, (ii) substituted or unsubstituted 5- or 6-membered heterocylic group, (iii) alkenylthio, (iv) pyrrolidinyl-alkyl--S--, (v) pyrrolidinyl-alkyl--SO--, (vi) pyrrolidinyl-alkyl--SO.sub.2 --, (vii) --O--B--NR.sup.4 R.sup.5 [B is alkylene having optionally OH, R.sup.4 is H, R.sup.5 is tricyclo[3.3.1.1]decanyl, tricyclo[3.3.1.1]decanylalkyl, etc., or R.sup.4 and R.sup.5 may together form a group of ##STR4## (R.sup.6 is substituted or unsubstituted amino)] or (viii) substituted alkoxy; m is 1 to 3]}, which have excellent vasopressin antagonistic activities and are useful as vasodilator, hypotensive agent, water diuretics, platelet agglutination inhibitor, and a vasopressin antagonistic composition containing the compound as the active ingredient.

Abstract: Novel benzoheterocyclic compounds of the formula: ##STR1## wherein R.sup.1 is H, halogen, OH, etc,; R.sup.2 is H, alkyl, halogen or alkoxy; R.sup.3 is phenyl-alkanoylamino, or ##STR2## R.sup.4 is H, --NR.sup.6 R.sup.7, alkenyloxy, HO-alkyl, --O--CO--A--NR.sup.8 R.sup.9, etc.; R.sup.5 is H, OH, etc., or a salt thereof, which have excellent vasopressin antagonistic activities and useful as vasodilator, hypotensive agent, water diuretics, platelet agglutination inhibitor, and a vasopressin antagonistic composition containing the compound as the active ingredient.

Abstract: A silver halide photographic light-sensitive material comprising a reflective support having a transmission density of not more than 0.8, having thereon, a photographic component layer comprising a silver halide emulsion layer and a layer including at least one anti-halation layer formed closer to said support than said silver halide emulsion layer is disclosed. In the photographic material, degradation of image sharpness due to use of a reflective support having low transmission density is prevented.

Abstract: In the production of a grain-oriented electrical steel sheet, instead of conventional inhibitors a novel (Al, Si)N inhibitor is utilized. This inhibitor is formed by obtaining an incomplete solution of Al and N and then nitriding the decarburization annealed steel sheet prior to initiation of a secondary recrystallization. The fine inhibitor can be formed in a large amount, thereby enhancing the magnetic flux density.

Abstract: A direct positive silver halide photographic light sensitive material including a support having thereon at least one silver halide emulsion layer containing internal latent image silver halide grains, each of the grains comprising a core/shell structured particle comprising a core, at least one intermediate layer, and an outermost layer formed thereon. The outermost layer consists essentially of silver chloride which accounts for no more than 10 mol % of the silver halide in the internal latent image silver halide grain. Such photographic materials display an increased sensitivity while maintaining an adequate image density.

Abstract: An annealing separator used in a finishing annealing step for producing a grain-oriented electrical steel sheet usually contains magnesia. The present invention is characterized by including, based on 100 parts by weight of magnesia, from 0.2 to 20 parts by weight of ferromanganese nitride or manganese nitride which consists of a composition (Mn.sub.1-x Fe.sub.x)N.sub.y having x and y values corresponding to A, B, C, and D and falling within a region surrounded by A, B, C, and D shown in the appended FIG. 1.The annealing separator according to the present invention is effective for stabilizing secondary recrystallization and improving the properties of a forsterite film.

Abstract: The present invention relates to a heat treatment process of high-carbon chromium-nickel heat-resistant stainless steels for the purpose of improving the creep rupture strength of the steel at temperatures over about 800.degree. C particularly at about 1000.degree. C.The feature of the present invention lies in that heat-resistant stainless steels containing 0.2 - 1.5% C, 15 - 40% Cr, 10 - 50% Ni, 5% or less Si, 15% or less Mn, with the balance Fe, and impurities are heated for 1 to 60 minutes in a temperature range from 1280.degree. C to 1350.degree. C and then quenched to room temperature at cooling rates higher than 200.degree. C/min. in order to produce the eutectic carbide structure consisted of the matrix metal and carbide phases in which M.sub.7 C.sub.3 -type carbide is contained not less than 25% by weight of the total weight of the carbides, that are present in the said eutectic carbide structure, at grain boundary triple points, along grain boundaries and within grains.