Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior Notch signal transduction inhibitory action, and is useful for preventing or treating various diseases involving Notch signal transduction.

Abstract: A compound of the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof has a superior inhibitory activity on cancer cell proliferation.

Abstract: A ventilator includes a heat exchanger including a plurality of layered partition members, and a housing that has a first end wall part covering one end side of the heat exchanger along a layering direction and a second end wall part covering the other end side of the heat exchanger, and partitions a periphery of the heat exchanger into an exhaust air flow inlet space, an exhaust air flow outlet space, a supply air flow inlet space, and a supply air flow outlet space. An exhaust air flow passes through the exhaust air flow outlet space during heat exchange ventilation, and passes through the supply air flow inlet space during normal ventilation. A supply air flow passes through the supply air flow inlet space during heat exchange ventilation, and passes through the exhaust air flow outlet space during normal ventilation.

Abstract: The present invention provides a new imidazole derivative represented by the following formula or a pharmaceutically acceptable salt thereof which exhibits potent antimicrobial activity based on a LpxC-inhibiting action against gram-negative bacteria such as Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae, and their drug-resistant strains. General formula [1] or [2].

Abstract: A ventilator includes a heat exchanger including a plurality of layered partition members, and a housing that has a first end wall part covering one end side of the heat exchanger along a layering direction and a second end wall part covering the other end side of the heat exchanger, and partitions a periphery of the heat exchanger into an exhaust air flow inlet space, an exhaust air flow outlet space, a supply air flow inlet space, and a supply air flow outlet space. An exhaust air flow passes through the exhaust air flow outlet space during heat exchange ventilation, and passes through the supply air flow inlet space during normal ventilation. A supply air flow passes through the supply air flow inlet space during heat exchange ventilation, and passes through the exhaust air flow outlet space during normal ventilation.

Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria. Provided is a hydroxamic acid derivative represented by the following general formula [1] or a pharmaceutically acceptable salt thereof.

Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.

Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.

Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.

Abstract: Provided is a novel compound which is useful as a pharmaceutical composition by inhibiting an LpxC activity, thereby exhibiting potent antimicrobial activity against gram-negative bacteria including Pseudomonas aeruginosa and its drug resistant bacteria.

Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.

Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.

Abstract: A pixel includes a photodiode, an overflow circuit, a first sensing circuit, and a second sensing circuit. The first sensing circuit charges and discharges a cathode capacitance by a photocurrent flowing through a photodiode, and amplifies an obtained voltage by a source follower amplifier so as to be outputted to a data line. The second sensing circuit charges and discharged the cathode capacitance by the photocurrent flowing through the photodiode, and outputs electric charge stored in the cathode capacitance via the data line. A pixel circuit is configured so that a first mode in which the first sensing circuit becomes active and a second mode in which the second sensing circuit becomes active can be switched. The first mode and the second mode are switched according to an amount of light received by the photodiode included in each pixel circuit. Gain is controlled according to the amount of light received, in the first mode, and the storage time is controlled in the second mode.

Abstract: In a photo detecting apparatus, a first capacitance is caused by a photo detecting element and the first capacitance is charged or discharged by current flowing through the photo detecting element. A second capacitance is connected in parallel with the photo detecting element, and the second capacitance charges or discharges an electric charge overflowing from the first capacitance. A current control element is connected to a terminal of the second capacitance on a side where the electric charge flows in, and the current control element delivers a current to cancel part of an electric charge when the electric charge overflowing from the first capacitance is stored in the second capacitance.

Abstract: A solid-state imaging device includes pixel cells that are formed on a substrate having a first substrate surface side, on which light is irradiated, and a second substrate surface side, on which elements are formed, and separated by an adjacent cell group and an element separation layer for each of the pixel cells or with plural pixel cells as a unit. Each of the pixel cells has a first conductive well formed on the first substrate surface side and a second conductive well formed on the second substrate surface side. The first conductive well receives light from the first substrate surface side and has a photoelectric conversion function and a charge accumulation function for the received light. A transistor that detects accumulated charges in the first conductive well and has a threshold modulation function is formed in the second conductive well.

Abstract: A pixel includes a photodiode, an overflow circuit, a first sensing circuit, and a second sensing circuit. The first sensing circuit charges and discharges a cathode capacitance by a photocurrent flowing through a photodiode, and amplifies an obtained voltage by a source follower amplifier so as to be outputted to a data line. The second sensing circuit charges and discharged the cathode capacitance by the photocurrent flowing through the photodiode, and outputs electric charge stored in the cathode capacitance via the data line. A pixel circuit is configured so that a first mode in which the first sensing circuit becomes active and a second mode in which the second sensing circuit becomes active can be switched. The first mode and the second mode are switched according to an amount of light received by the photodiode included in each pixel circuit. Gain is controlled according to the amount of light received, in the first mode, and the storage time is controlled in the second mode.

Abstract: A pixel circuit includes a first detector which amplifies a voltage obtained by charging and discharging a capacitance with a photocurrent flowing through a photo detecting element and then outputs it to a first data line, and a second detector which outputs an electric charge stored in the capacitance by the photocurrent, to a second data line. The pixel circuit operates in a first operation mode where the first detector is activated, a second operation mode where the second detector is activated and an initialization mode where the photo detecting element is initialized. With a first transistor turned on, the second detector outputs an electric charge stored in the capacitance in the second operation mode, and in the initialization mode a reset voltage set in the second data line is applied to the other end of the photo detecting element to initialize the photo detecting element.

Abstract: When parallel processing is executed by parallel computers composed of a host computer and a plurality of processors connected to the host computer through a common bus, there is provided a method of assigning jobs to respective processors with high efficiency. A job in which a ratio between a communication time and a calculation time is larger than a predetermined value or larger than a fraction of processors and a job in which a ratio between a communication time and a calculation time is smaller than a predetermined value or smaller than a fraction of processors can be alternately assigned to respective processors.

Abstract: In a photo detecting apparatus, a first capacitance is caused by a photo detecting element and the first capacitance is charged or discharged by current flowing through the photo detecting element. A second capacitance is connected in parallel with the photo detecting element, and the second capacitance charges or discharges an electric charge overflowing from the first capacitance. A current control element is connected to a terminal of the second capacitance on a side where the electric charge flows in, and the current control element delivers a current to cancel part of an electric charge when the electric charge overflowing from the first capacitance is stored in the second capacitance.

Abstract: A plurality of pixel circuits, provided with a plurality of photo detecting elements, respectively, cause photocurrent corresponding to an incident light. The pixel circuits are placed on intersections of a plurality of data lines and scanning lines, respectively. A second capacitance charges and discharges an electric charge overflowing from a first capacitance caused by the photo detecting element. Each second capacitance is shared by a plurality of pixel circuits. A plurality of pixel circuits sharing the second capacitance are controlled so that exposure periods of the pixel circuits do not overlap with one another.