Patents by Inventor Hajimu Sakamoto

Hajimu Sakamoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for stabilizing a tumor necrosis factor and a stable aqueous solution or powder containing the same
    Patent number: 4447355
    Abstract: A method for stabilizing a Tumor Necrosis Factor (TNF), which comprises adding at least one member selected from the group consisting of an albumin, a gelatin, a globulin, a protamine and a salt of protamine to an aqueous solution or powder containing TNF, and a stable aqueous solution or powder which contains TNF and an effective amount of such a protein. The aqueous solution or powder containing TNF can be stored for a prolonged period of time without losing its activity, and is stable on freezing, thawing, lyophilization or the like.
    Type: Grant
    Filed: March 23, 1983
    Date of Patent: May 8, 1984
    Assignees: Asahi Kasei Kogyo Kabushiki Kaisha, Dainippon Pharmaceutical Co., Ltd.
    Inventors: Hajimu Sakamoto, Takao Kiyota, Hiroshi Hayashi
  • Process for producing plasminogen activator
    Patent number: 4328314
    Abstract: In the production of plasminogen activator from animal cells in a nutrient solution, the addition of a large amount of fumaric acid, malic acid, succinic acid, and/or glycolic acid to the nutrient solution brings about a 30 to 180% increase in the amount of plasminogen activator produced.
    Type: Grant
    Filed: November 26, 1979
    Date of Patent: May 4, 1982
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Sadayuki Horiguchi, Akio Hasegawa, Hajimu Sakamoto