Abstract: Described is a nucleic acid molecule comprising (a) a nucleic acid sequence encoding the monocyte-chemoattractant-protein-1 (MCP-1) or a protein having the biological activity of the monocyte-chemoattractant-protein-1 (MCP-1) and (b) a hypersensitivity region. Also described are pharmaceutical compositions for the treatment of diseases associated with dysregulation of MCP-1 expression, e.g. atherosclerosis or cancer.

Abstract: A device for simultaneously or sequentially carrying out chemical reactions ncludes a stack of four rods; and a carrier plate which is displaceable. The stack of four rods is composed of a first rod which has a position which is fixed and which has a plurality of throughgoing bores defined therein; a second rod which is in contact with the first rod, which is fixedly connected to the carrier plate so that the second rod is displaceable, and which has a throughgoing bore defined therethrough; a third rod which is in contact with the second rod, which is disposed so that it is displaceable by the carrier plate, arid which has defined therein a plurality of reaction chambers which are provided with two openings located opposite one another and which are present in a number n; and a fourth rod which is in contact with the third rod, which is fixedly connected to the carrier plate, and which has a throughgoing bore defined therein.