Abstract: In one aspect, the present disclosure relates to a method of adaptive treatment of a subject with a tumor. The method may include administering a first pulse dose of radiation to a tumor within a subject; administering a second pulse dose of radiation to the tumor, wherein the second pulse dose is administered after an observation period, the observation period having a duration of at least 7 days; and concurrently treating the subject with an immunotherapy.

Abstract: Various examples of methods, systems, apparatus and devices are provided for MRI adaptation for radiotherapy machines. In one example, a system for MRI-guided radiotherapy can include a mounting ring and superconducting magnets. The mounting ring can be installed on a gantry of a LINAC to rotate about an isocenter of the LINAC moving with the gantry. The first and second superconducting magnet can be positioned substantially parallel to each other at a separation distance with the centers substantially aligned. The first and second superconducting magnets can provide a main magnetic field within a region of interest located between the first and second superconducting magnets. The superconducting magnets can have an aperture positioned at the center of each magnet and can allow a radiotherapy beam emitting from the gantry head to pass through the apertures. In another example, superconducting magnets can be installed at opposite ends of a LINAC gantry.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: A method for determining the screen brightness in the electronic device includes determining whether a flip cover opens or closes a screen when the screen display event occurs, determining a first brightness value for a full screen display mode when the flip cover is opened, and determining a second brightens value for a flip covered window display. Other embodiments including an apparatus for determining the screen brightness are also disclosed.

Abstract: Radiation therapy systems and their components, including secondary radiation shields. At least some versions of the disclosed systems combine a radiation delivery device, a primary radiation shielding device, and a secondary shielding layer into an integrated, modular unit. This is accomplished by using a small direct beam shield capable of blocking a primary beam from a radiation delivery device. In turn, a thinner shielding layer can be used to surround the radiation delivery device and primary shielding device, enabling a single modular unit to be delivered to an installation site. In some embodiments, a bed may be disposed within the secondary shielding layer. In some embodiments, the system is configured to provide up to 4-pi (4?) steradians of radiation coverage to the bed from the radiation delivery device.

Abstract: A method for determining the screen brightness in the electronic device includes determining whether a flip cover opens or closes a screen when the screen display event occurs, determining a first brightness value for a full screen display mode when the flip cover is opened, and determining a second brightens value for a flip covered window display. Other embodiments including an apparatus for determining the screen brightness are also disclosed.

Abstract: Disclosed is a method of enhancing the therapeutic effect of radiation in a host being treated for cancer including coadministering the radiation and an orally dosed camptothecin derivative to the host being treated for cancer. Also disclosed is a method of enhancing the therapeutic effect of radiation in a host being treated for cancer including orally dosing the host being treated for cancer with a camptothecin derivative; and administering radiation at a point when a serum concentration of the camptothecin derivative in the host being treated for cancer reaches about 50% or more of the maximum concentration achieved by the oral dose.