Patents by Inventor Hakan KÖKSAL

Hakan KÖKSAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TWO CHIMERIC ANTIGEN RECEPTORS SPECIFICALLY BINDING CD19 AND IGKAPPA
    Publication number: 20220177573
    Abstract: The present disclosure relates to compositions comprising compounds or cells able to specifically bind immunoglobulin kappa (IgKappa) and membrane molecule CD 19 under physiological conditions. In particular, the disclosure relates to a combinatorial chimeric antigen receptor (cCAR) with antigen binding domains specific for the antigen CD19 and the immunoglobulin (Ig) Kappa light chain and their expression in immune effector cells to target cells expressing CD19 and IgKappa, and such immune cells for use in treating B-cell cancers.
    Type: Application
    Filed: July 8, 2019
    Publication date: June 9, 2022
    Inventors: Gunnar Kvalheim, Erlend Smeland, Else Marit Inderberg, Sébastien Wälchli, Harald Holte, June Helen Myklebust, Steinar Funderud, Hakan Köksal
  • CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20200308279
    Abstract: Provided herein are compositions and methods for immunotherapy. In particular, provided herein are chimeric antigen receptors, cells expressing chimeric antigen receptors, and use of such cells in immunotherapy (e.g., cancer immunotherapy).
    Type: Application
    Filed: March 5, 2018
    Publication date: October 1, 2020
    Inventors: Sébastien WÄLCHLI, Even WALSENG, Else Marit INDERBERG, Hakan KÖKSAL