Abstract: Disclosed herein is desloratadine for use in the treatment and/or prophylactic treatment of lung cancer, prostate cancer, pancreatic cancer, gastric cancer, kidney cancer, ovarian cancer, colorectal cancer, Hodgins's disease, bladder cancer, liver cancer, and/or nasopharyngeal cancer.

Abstract: It is provided a method for managing central secret keys of a plurality of user devices associated with a single public key. The method is performed in a key manager and comprises the steps of: receiving, from a first user device, transformation data and an identifier of a second user device; obtaining a first central secret key associated with the first user device; generating a second central secret key by applying the transformation data to the first central secret key, wherein the transformation data is applied in reverse to how the same transformation data is applied by the first user device to a device secret key of the first user device; and storing the second central secret key in association with the second user device.

Abstract: A method including: repeatedly obtaining information in a control unit regarding a set operation value and an actual operation value of a component, unit, or system; repeatedly evaluating a difference between a set operation value and the actual operation value; if a difference exceeds a predefined minimum difference, measuring a response time from when the minimum difference was exceeded until a predefined change of the actual value is achieved, and/or measuring a change of the actual value during a predefined response time, remaining active if the set operation value is continuously exceeds the actual value; and if the response time is longer than the predefined response time and/or if the change of the actual value has not achieved the predefined change, generating a fault signal.

Abstract: Disclosed herein is a pharmaceutical composition comprising a H1 antihistamine being desloratadine and/or loratadine, for use in the treatment and/or prophylactic treatment of melanoma.

Abstract: It is provided a method for determining a location of a mobile device. The method comprises the steps of: obtaining a first maximum distance between a first anchor point and the mobile device; generating a first circular geometrical object having a radius based on the first maximum distance; generating a first polytope encompassing the first circular geometric object, wherein all angles of the first polytope are right angles; obtaining a second maximum distance between a second anchor point and the mobile device; generating a second circular geometrical object having radius based on the second maximum distance; generating a second polytope encompassing the second circular geometric object, wherein all angles of the second polytope are right angles; finding a mobile device region as an overlap between the first polytope and the second polytope; and determining that the mobile device is located within the mobile device region.

Abstract: It is provided a method for controlling access to a physical space. The method is performed in an access control device and comprises the steps of: communicating with an electronic key to obtain an identity of the electronic key; obtaining a plurality of delegations; determining, from one of the delegations, that there is an auxiliary condition, wherein the auxiliary condition is that access is approved for the electronic key by an auxiliary party, authenticated by a digital signature by the auxiliary party; and granting access to the physical space when the plurality of delegations comprises a sequence of delegations covering a delegation path from the access control device to the electronic key such that, in the sequence of delegations, the delegator of the first delegation is the access control device, the receiver of the last delegation is the electronic key, and the auxiliary condition is fulfilled.

Abstract: It is presented a method for determining whether a portable key device is located in an active area in relation to a barrier. The method is performed in an access control device and comprises the steps of: detecting an angle of arrival of a wireless signal from the portable key device using a pair of antennas provided such that a line between the pair of antennas crosses the barrier; and determining whether the portable key device is located within the active area based on the angle of arrival.

Abstract: It is provided a method for providing connectivity for a plurality of Internet of Things, IoT, devices. The method is performed in a connectivity device and comprises the steps of: detecting presence of a connector unit in one of a plurality of connector interfaces; obtaining connection data from the connector unit, the connection data being associated with a specific IoT device; connecting, using a wireless communication module of the connectivity device, to the IoT device using the connection data associated with the IoT device; and wherein the method is repeated for a plurality of connector units.

Abstract: It is provided a method for managing central secret keys of a plurality of user devices associated with a single public key. The method is performed in a key manager and comprises the steps of: receiving, from a first user device, transformation data and an identifier of a second user device; obtaining a first central secret key associated with the first user device; generating a second central secret key by applying the transformation data to the first central secret key, wherein the transformation data is applied in reverse to how the same transformation data is applied by the first user device to a device secret key of the first user device; and storing the second central secret key in association with the second user device.

Abstract: It is provided a method for determining a location of a mobile device. The method comprises the steps of: obtaining a first maximum distance between a first anchor point and the mobile device; generating a first circular geometrical object having a radius based on the first maximum distance; generating a first polytope encompassing the first circular geometric object, wherein all angles of the first polytope are right angles; obtaining a second maximum distance between a second anchor point and the mobile device; generating a second circular geometrical object having radius based on the second maximum distance; generating a second polytope encompassing the second circular geometric object, wherein all angles of the second polytope are right angles; finding a mobile device region as an overlap between the first polytope and the second polytope; and determining that the mobile device is located within the mobile device region.

Abstract: It is provided a method for controlling access to a physical space. The method is performed in an access control device and comprises the steps of: communicating with an electronic key to obtain an identity of the electronic key; obtaining a plurality of delegations; determining, from one of the delegations, that there is an auxiliary condition, wherein the auxiliary condition is that access is approved for the electronic key by an auxiliary party, authenticated by a digital signature by the auxiliary party; and granting access to the physical space when the plurality of delegations comprises a sequence of delegations covering a delegation path from the access control device to the electronic key such that, in the sequence of delegations, the delegator of the first delegation is the access control device, the receiver of the last delegation is the electronic key, and the auxiliary condition is fulfilled.

Abstract: Disclosed herein is desloratadine or ebastin for use in treatment of a patient diagnosed with breast cancer. Also disclosed is desloratadine or ebastin for use in treatment of a patient diagnosed with a cancer type susceptible to immunotherapy.

Abstract: A composition for use in the treatment and/or prophylactic treatment of breast cancer includes a 5-Alpha Reductase Inhibitor (5-ARI) and an excipient.

Abstract: It is presented a method for determining whether a portable key device is located in an active area in relation to a barrier. The method is performed in an access control device and comprises the steps of: detecting an angle of arrival of a wireless signal from the portable key device using a pair of antennas provided such that a line between the pair of antennas crosses the barrier; and determining whether the portable key device is located within the active area based on the angle of arrival.

Abstract: Disclosed herein is desloratadine or ebastin for use in treatment of a patient diagnosed with breast cancer. Also disclosed is desloratadine or ebastin for use in treatment of a patient diagnosed with a cancer type susceptible to immunotherapy.

Abstract: The present invention relates to a method and a device for ensuring information integrity and non-repudiation over time. At least one example embodiment provides a mechanism for secure distribution of information, which information relates to an instance in time when usage of cryptographic key pairs associated with a certain brand identity commenced, as well as when the key pairs ceased to be used, i.e. when the key pairs were revoked. The mechanism further allows a company or an organization to tie administration of cryptographic key pairs and a procedure for verifying information integrity and non-repudiation to their own brand. This can be seen as a complement or an alternative to using a certificate authority (CA) as a trusted third party, which CA guarantees an alleged relation between a public key and the identity of the company or organization using the cryptographic key pair to which that public key belongs.

Abstract: Twist drill for short hole drilling with two chip flutes opening in a clearance surface of a front tip to form, with the clearance surface, two cutting edges. Chip flutes have three different part surfaces having different curvatures—a bottom surface with arc radius less than 10 mm and two other ones with radius of curvature approaching infinity. Boundary line between concave bottom surface and heading frontal surface meets a main edge that is included in the individual cutting edge and divided into two edge segments imparting a J-like shape to the main edge. The chip flute is extraordinary deep with the diameter (DC) of the core reduced to a minimum and the opening angle (?) smaller than the angle of divergence (?) of two bars, between which the flutes are countersunk. The drill improves-formation and evacuation of chips, is easy-cutting and requires a minimum of energy.

Abstract: The present invention relates to a method and a device for ensuring information integrity and non-repudiation over time. At least one example embodiment provides a mechanism for secure distribution of information, which information relates to an instance in time when usage of cryptographic key pairs associated with a certain brand identity commenced, as well as when the key pairs ceased to be used, i.e. when the key pairs were reyoked. The mechanism further allows a company or an organization to tie administration of cryptographic key pairs and a procedure for verifying information integrity and non-repudiation to their own brand. This can be seen as a complement or an alternative to using a certificate authority (CA) as a trusted third party, which CA guarantees an alleged relation between a public key and the identity of the company or organization using the cryptographic key pair to which that public key belongs.

Abstract: The present invention relates to a method and a device for ensuring information integrity and non-repudiation over time. A basic idea of the present invention is to provide a mechanism for secure distribution of information, which information relates to an instance in time when usage of cryptographic key pairs associated with a certain brand identity commenced, as well as when the key pairs ceased to be used, i.e. when the key pairs were revoked. The mechanism further allows a company or an organization to tie administration of cryptographic key pairs and a procedure for verifying information integrity and non-repudiation to their own brand. This can be seen as a complement or an alternative to using a certificate authority (CA) as a trusted third party, which CA guarantees an alleged relation between a public key and the identity of the company or organization using the cryptographic key pair to which that public key belongs.