Abstract: The use of an automated, controllable, and affixable pulsatile for treating diseases, having an automated controller for controlling the delivery of drug to a patient, an agent delivery reservoir containing an agent operatively connected to the automated controller, a reservoir controller operatively connected to the automated controller and the reservoir for controlling the delivery of agent to a patient, and a feedback control operatively connected to the automated controller for providing feedback with regard to the drug requirements of the patient for use in treating diseases.

Abstract: An automated, controllable, and affixable pulsatile agent delivery system having an automated controller for controlling the delivery of drug to a patient, an agent delivery reservoir containing an agent operatively connected to the automated controller, a reservoir controller operatively connected to the automated controller and the reservoir for controlling the delivery of agent to a patient, and a feedback control operatively connected to the automated controller for providing feedback with regard to the drug requirements of the patient. A method of delivering an agent to a patient in need of the same by administering the above agent delivery system to a patient, determining an amount of agent needed for the patient, and affecting administration of the agent to the patient via the agent delivery system.

Abstract: The present invention relates to a cell culture chamber (10) having a sterile environment (12) for the culture of cells, a cover (14) for allowing for a transfer of pits and a sensor array.

Abstract: According to the present invention, there is provided a micro-fluidic sensor system (6) including a micro-conduit (56) for carrying fluid therethrough having a flexible wall portion (18), at least one micro-fluidic actuator having a closed cavity, flexible mechanism defining a wall of the cavity (11) and flexible wall portion (18) of the micro-conduit for deflecting upon an application of pressure thereto, and expanding mechanism (14) disposed in the cavity for selectively expanding the cavity and thereby selectively flexing said expanding mechanism, and sensor mechanism in fluid communication with the micro-conduit for sensing the presence or absence of molecules. The present invention further provides for a micro-fluidic system for moving micro-fluid amounts including a micro-conduit and at least one micro-fluidic actuator in fluid communication with the micro-conduit.

Abstract: According to the present invention, there is provided a pulsating micro chamber including a walled chamber. The walled chamber further includes at least one pulsating portion actuable to pulse and change an interior volume of the walled chamber. The present invention further provides for a micro-fluidic pump including a micro conduit for carrying fluid therethrough and at least one actuating mechanism for peristaltically moving fluids through the micro conduit. The actuating mechanism includes a closed pocket adjacent to the conduit, a flexible mechanism defining a portion of a wall of the micro conduit, and an expanding mechanism disposed within the pocket for expanding a volume of the pocket and thereby flexing the flexible mechanism into the micro conduit thereby changing the volume of the conduit.

Abstract: According to the present invention, there is provided a micro-fluidic valve including a micro conduit for carrying fluid therethrough and at least one micro actuating mechanism for selectively deflecting at least a portion of a wall of the micro conduit occluding fluid flow through the micro conduit. Additionally, the present invention provides for a mono-stable micro-fluidic valve and for a bi-stable micro-fluidic valve.