Abstract: A drinking container having a removable, freezable member. The drinking container has a cylindrical inner receptacle and a surrounding cylindrical outer receptacle. An annular chamber is formed between the inner and outer receptacles. A refrigerant member comprising a plastic envelope containing a freezable gel is dimensioned to fit into the annular chamber, and is readily removable therefrom. A cap engages the drinking container to retain the refrigerant member once placed in the annular chamber. The refrigerant member is preferably an annular sleeve which slips between the inner and outer receptacles, and folds flat for storage and freezing. The inner receptacle projects above the outer receptacle so that the user is obliged to engage only one wall with the mouth and lips, thereby enjoying comfortable drinking, rather than being obliged to span the combined thickness of the inner and outer receptacle walls together with the refrigerant member when drinking.

Abstract: A group of .beta.-blockers represented by the formula ##STR1## wherein R is ##STR2## or ##STR3## and the physiologically compatible acid addition salts thereof. These .beta.-blockers are .beta.-adrenergic receptor blocking agents which are useful in the treatment of angina pectoris, heart arrhythmia, and high blood pressure.

Abstract: Adenosine-5'-carboxylic acid amides represented by the formula ##STR1## wherein R.sub.1 and R.sub.2 are each selected from the group consisting of hydrogen, loweralkyl, lowerhaloalkyl, lowerhydroxyalkyl, lowercycloalkyl, loweralkylcycloalkyl, loweralkenyl, lowerhaloalkenyl, lowerhydroxyalkenyl, loweralkynyl, lowerhaloalkynyl, benzylamino, phenyl, loweralkylphenyl, loweralkoxyloweralkyl, substituted phenyl, 2-methylfuran or di(C.sub.1 -C.sub.4)alkylamino(C.sub.1 -C.sub.4)alkyl, adamantyl or R.sub.1 and R.sub.2 taken together form a 5 or 6 membered heterocyclic moiety; R.sub.3 and R.sub.4 are hydrogen or acyl, or taken together form an isopropylidene or a benzylidene group; or a pharmaceutically acceptable acid addition salt thereof.

Abstract: 2-Substituted adenosine-5'-carboxylates represented by the formula ##SPC1##Wherein R is amino, acetamido or hydroxy, R.sub.1 is loweralkyl, haloloweralkyl, hydroxyloweralkyl, lowercycloalkyl, loweralkenyl, loweralkynyl, loweralkyl(C.sub.3 -C.sub.6)cycloalkyl or alkoxyalkyl and R.sub.2 and R.sub.3 each are hydrogen or acyl, or R.sub.2 and R.sub.3 taken together form an isopropylidene or benzylidene moiety; and the pharmaceutically acceptable acid addition salts thereof. The compounds wherein R.sub.2 and R.sub.3 are hydrogen or acyl are useful in treating cardiovascular disorders and are particularly useful as anti-anginal agents. Compounds wherein R.sub.2 and R.sub.3 when taken together form an isopropylidene or benzylidene moiety are intermediates useful in making the final products.

Abstract: Adenosine-5'-carboxamides which are effective as platelet aggregation inhibitors and represented by the formula ##SPC1##Wherein R is hydrogen, loweralkyl, lowercycloalkyl, loweralkenyl, or lowerhydroxyalkyl.