Patents by Inventor Hala J. Tomey
Hala J. Tomey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10376682Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: GrantFiled: October 11, 2016Date of Patent: August 13, 2019Assignee: The Johns Hopkins UniversityInventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Resar, Robert C. Matteson, III, George L. Coles, Jr., Jason J. Benkoski, Morgana M. Trexler
-
Patent number: 9825701Abstract: An optical communications beacon receiver including a camera for capturing a plurality of beacon images. The plurality of beacon images includes a beacon signal transmitted from a beacon transmitter. The beacon receiver also including processing circuitry configured for determining the state of the beacon signal for each of the plurality of beacon images based on the known pattern, at least one beacon image of the plurality of beacon images includes a beacon on state and at least one beacon image of the plurality of beacon images includes a beacon off state, comparing the at least one beacon image including the beacon on state to the at least one beacon image including the beacon off state, and determining a beacon location based on the comparison of the at least one beacon image including the beacon on state to the at least one beacon image including the beacon off state.Type: GrantFiled: October 12, 2015Date of Patent: November 21, 2017Assignee: The Johns Hopkins UniversityInventors: Juan C. Juarez, Radha A. Venkat, Ricardo Luna, David A. Kitchin, Melissa E. Jansen, David W. Young, Katherine T. Souza, Joseph E. Sluz, David M. Brown, Ryan P. DiNello-Fass, Hala J. Tomey
-
Publication number: 20170028181Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: ApplicationFiled: October 11, 2016Publication date: February 2, 2017Inventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Resar, Robert C. Matteson, III, George L. Coles, JR., Jason J. Benkoski, Morgana M. Trexler
-
Patent number: 9504586Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: GrantFiled: February 13, 2014Date of Patent: November 29, 2016Assignee: The Johns Hopkins UniversityInventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Resar, Robert C. Matteson, III, George L. Coles, Jr., Jason J. Benkoski, Morgana M. Trexler
-
Publication number: 20160112124Abstract: An optical communications beacon receiver including a camera for capturing a plurality of beacon images. The plurality of beacon images includes a beacon signal transmitted from a beacon transmitter. The beacon receiver also including processing circuitry configured for determining the state of the beacon signal for each of the plurality of beacon images based on the known pattern, at least one beacon image of the plurality of beacon images includes a beacon on state and at least one beacon image of the plurality of beacon images includes a beacon off state, comparing the at least one beacon image including the beacon on state to the at least one beacon image including the beacon off state, and determining a beacon location based on the comparison of the at least one beacon image including the beacon on state to the at least one beacon image including the beacon off state.Type: ApplicationFiled: October 12, 2015Publication date: April 21, 2016Inventors: Juan C. Juarez, Radha A. Venkat, Ricardo Luna, David A. Kitchin, Melissa E. Jansen, David W. Young, Katherine T. Souza, Joseph E. Sluz, David M. Brown, Ryan P. DiNello-Fass, Hala J. Tomey
-
Publication number: 20140188213Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: ApplicationFiled: February 13, 2014Publication date: July 3, 2014Applicant: Johns Hopkins UniversityInventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Rosar, Robert C. Matteson, George L/ Coles, Jason J. Benkoski, Morgana M. Trexler
-
Patent number: 8696740Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: GrantFiled: January 5, 2011Date of Patent: April 15, 2014Assignee: The Johns Hopkins UniversityInventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Rosar, Robert C. Matteson, III, George L. Coles, Jr., Jason J. Benkoski, Morgana M. Trexler
-
Publication number: 20120010698Abstract: Implantable pressure-actuated systems to deliver a drug and/or other substance in response to a pressure difference between a system cavity and an exterior environment, and methods of fabrication and use. A pressure-rupturable membrane diaphragm may be tuned to rupture at a desired rupture threshold, rupture site, with a desired rupture pattern, and/or within a desired rupture time. Tuning may include material selection, thickness control, surface patterning, substrate support patterning. The cavity may be pressurized above or evacuated below the rupture threshold, and a diaphragm-protective layer may be provided to prevent premature rupture in an ambient environment and to dissipate within an implant environment. A drug delivery system may be implemented within a stent to release a substance upon a decrease in blood pressure. The cavity may include a thrombolytic drug to or other substance to treat a blood clot.Type: ApplicationFiled: January 5, 2011Publication date: January 12, 2012Inventors: Chao-Wei Hwang, Hala J. Tomey, Jon R. Rosar, Robert C. Matteson, III, George L. Coles, JR., Jason J. Benkoski, Morgana M. Trexler