Publication number: 20230181649
Abstract: The present invention provides method of treating diseases, disorders and conditions in a human subject comprising administering to the subject a population of exosomes or a composition comprising a population of exosomes, wherein said population of exosomes is positive for CD1c, CD20, CD24, CD25, CD29, CD2, CD3, CD8, CD9, CD11c, CD14, CD19, CD31, CD40, CD41b, CD42a, CD44, CD45, CD49e, CD4, CD56, CD62P, CD63, CD69, CD81, CD86, CD105, CD133-1, CD142, CD146, CD209, CD326, HLA-ABC, HLA-DRDPDQ, MCSP, ROR1, SSEA-4, or combinations thereof. Such diseases, disorders and conditions include lung, liver, central nervous system, kidney, cardiovascular, gastrointestinal, spleen, eye, systemic and ageing associated diseases, disorders, and conditions.
Type:
Application
Filed:
June 19, 2020
Publication date:
June 15, 2023
Applicant:
Celularity Inc.
Inventors:
Robert J. HARIRI, Xiaokui ZHANG, Qian YE, Bhavani STOUT, Haley M. HARIRI, Navjot SHAH, Srinivas Somanchi, Shuyang He