Patents by Inventor Haley R. Kermis

Haley R. Kermis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ratiometric fluorescent pH sensor for non-invasive monitoring
    Patent number: 7390462
    Abstract: The present invention provides ratiometric fluorescent pH sensors for non-invasive, continuous monitoring of pH in such applications as fermentation processes. The ratiometric fluorescent pH sensors comprise a fluorescent dye that exhibits a shift in excitation wavelength with a corresponding shift in pH in the local environment of said fluorescent dye. Ratiometric measurements of the emission intensities at dual excitation maxima correlate to pH. Also provided is a fluorescent dye 6-methacryloyl-8-hydroxy-1,3-pyrene disulfonic acid (MA-HPDS). Further provided are systems and methods to non-invasively and continuously monitor pH.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: June 24, 2008
    Assignee: The University of Maryland Baltimore County
    Inventors: Govind Rao, Iordan V. Kostov, Haley R. Kermis, Peter Harms