Patents by Inventor Hamid Rezaei

Hamid Rezaei has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
    Publication number: 20220339111
    Abstract: The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
    Type: Application
    Filed: April 15, 2022
    Publication date: October 27, 2022
    Applicant: Genentech, Inc.
    Inventors: Sanjeev KOTHARI, Priscilla MANTIK, Alexander MAUERER, Hamid REZAEI
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20220184079
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Application
    Filed: March 2, 2022
    Publication date: June 16, 2022
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • SOLID FORMS OF A COMPOUND FOR MODULATING KINASES
    Publication number: 20220081436
    Abstract: Forms of 4-(6-(3,5-dimethylisoxazol-4-yl)-1-[(1S)-1-(2-pyridyl)ethyl]pyrrolo[3,2-b]pyridin-3-yl)benzoic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I.
    Type: Application
    Filed: July 6, 2021
    Publication date: March 17, 2022
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Marika Nespi, Ben Powell, Rashmin Patel
  • Formulations of a compound modulating kinases
    Patent number: 11103505
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: August 31, 2021
    Assignee: Plexxikon Inc.
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • Formulations of a compound modulating kinases
    Patent number: 10961240
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 30, 2021
    Assignees: Plexxikon Inc., Daiichi Sankyo Company, Limited
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Formulations of a compound modulating kinases
    Patent number: 10941142
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 9, 2021
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • SOLID FORMS OF A COMPOUND FOR MODULATING KINASES
    Publication number: 20200299293
    Abstract: Forms of 4-(6-(3,5-dimethylisoxazol-4-yl)-1-[(1S)-1-(2-pyridyl)ethyl]pyrrolo[3,2-b]pyridin-3-yl)benzoic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 24, 2020
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Marika Nespi, Ben Powell, Rashmin Patel
  • Solid forms of a compound for modulating kinases
    Patent number: 10717735
    Abstract: Forms of 4-(6-(3,5-dimethylisoxazol-4-yl)-1-[(1S)-1-(2-pyridyl)ethyl]pyrrolo[3,2-b]pyridin-3-yl)benzoic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: July 21, 2020
    Assignee: Plexxikon Inc.
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Marika Nespi, Ben Powell, Rashmin Patel
  • IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
    Publication number: 20200085749
    Abstract: The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
    Type: Application
    Filed: November 15, 2019
    Publication date: March 19, 2020
    Applicant: Genentech, Inc.
    Inventors: Sanjeev Kothari, Priscilla Mantik, Alexander Mauerer, Hamid Rezaei
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20200010465
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 9, 2020
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Immediate-release tablets containing combimetinib and methods of making and using the same
    Patent number: 10478400
    Abstract: The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: November 19, 2019
    Assignee: Genentech, Inc.
    Inventors: Sanjeev Kothari, Priscilla Mantik, Alexander Mauerer, Hamid Rezaei
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190337944
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 7, 2019
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • Formulations of a compound modulating kinases
    Patent number: 10435404
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: October 8, 2019
    Assignees: Plexxikon Inc., Daiichi Sankyo Company, Limited
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • SOLID FORMS OF A COMPOUND FOR MODULATING KINASES
    Publication number: 20190161484
    Abstract: Forms of 4-(6-(3,5-dimethylisoxazol-4-yl)-1-[(1S)-1-(2-pyridyl)ethyl]pyrrolo[3,2-b]pyridin-3-yl)benzoic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I.
    Type: Application
    Filed: October 11, 2018
    Publication date: May 30, 2019
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Marika Nespi, Ben Powell, Rashmin Patel
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190125747
    Abstract: Provided are solid dispersions of Compound I having the formula: wherein Compound I is substantially amorphous, methods of manufacturing said solid dispersions, and methods of using said solid dispersions.
    Type: Application
    Filed: October 26, 2018
    Publication date: May 2, 2019
    Inventors: Hamid Rezaei, Marika Nespi, Prabha N. Ibrahim, Gary Conard Visor
  • FORMULATIONS OF A COMPOUND MODULATING KINASES
    Publication number: 20190031654
    Abstract: Provided are compositions comprising Compound I having the following structure: or a pharmaceutically acceptable salt thereof, and a solubilizing agent; methods of making the same; and methods of using the same.
    Type: Application
    Filed: July 24, 2018
    Publication date: January 31, 2019
    Inventors: Prabha N. Ibrahim, Hamid Rezaei, Gary Conard Visor, Tomoari Kamo, Hiroshi Yamakose
  • IMMEDIATE-RELEASE TABLETS CONTAINING A DRUG AND PROCESSES FOR FORMING THE TABLETS
    Publication number: 20180116966
    Abstract: The present disclosure relates generally to rapid-release pharmaceutical dosage unit tablets containing a drug that is an inhibitor of the mitogen-activated protein kinase enzyme, a filler and a disintegrant, and to processes for forming the tablets. More specifically, the present disclosure relates to pharmaceutical dosage unit tablets containing cobimetinib, a least one filler, at least one lubricant and at least one disintegrant, and to methods for preparing the tablets from granules formed by dry granulation.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 3, 2018
    Applicant: Genentech, Inc.
    Inventors: Sanjeev Kothari, Priscilla Mantik, Alexander Mauerer, Hamid Rezaei