Patents by Inventor Hamilton H. Yong

Hamilton H. Yong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for treating obesity by targeting cathepsin
    Publication number: 20040009891
    Abstract: Methods and compositions are provided for modulating fat storage of animals by targeting the gene and gene products of cathepsins, particularly cathepsins L, K, and S, and especially cathepsin L. The method comprises: administering to the animal an agent that reduces an in vivo level of cathepsin L activity such that fat storage by the animal is reduced. The methods of the present invention can be used to diagnose obesity, diabetes and related diseases such as hyperinsulinmia, hyperglycermia, hypertension, cardiovascular diseases, muscular dystrophy and infertility, as well as to screen for agents that can be used therapeutics for these diseases.
    Type: Application
    Filed: June 12, 2003
    Publication date: January 15, 2004
    Applicant: NewMillennium Pharmaceutical, Inc.
    Inventors: Hamilton H. Yong, Jingming Chen, Guo-Ping Shi
  • Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
    Patent number: 6620844
    Abstract: Methods and compositions are provided for modulating blood insulin levels of animals by targeting the gene and gene products of cathepsins, particularly cathepsins L, K, and S, and especially cathepsin L. The method comprises: administering to the animal an agent that reduces an in vivo level of cathepsin L activity such that the blood insulin level of the animal is reduced. The method can be used to treat hyperinsulinmia and related diseases such as insulin resistance, type II diabetes, and hyperglycermia.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: September 16, 2003
    Assignee: NewMillennium Pharmaceutical, Inc.
    Inventors: Hamilton H. Yong, Jingming Chen, Guo-ping Shi
  • Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
    Publication number: 20030054984
    Abstract: Methods and compositions are provided for modulating blood insulin levels of animals by targeting the gene and gene products of cathepsins, particularly cathepsins L, K, and S, and especially cathepsin L. The method comprises: administering to the animal an agent that reduces an in vivo level of cathepsin L activity such that the blood insulin level of the animal is reduced. The method can be used to treat hyperinsulinmia and related diseases such as insulin resistance, type II diabetes, and hyperglycermia.
    Type: Application
    Filed: February 14, 2001
    Publication date: March 20, 2003
    Inventors: Hamilton H. Yong, Jingming Chen
  • Method for treating diabetes by reducing in vivo cathepsin L activity
    Publication number: 20030050260
    Abstract: Methods and compositions are provided for modulating blood sugar levels of animals by targeting the gene and gene products of cathepsins, particularly cathepsins L, K, and S, and especially cathepsin L. The method comprises: administering to the animal an agent that reduces an in vivo level of cathepsin L activity such that the blood sugar level of the animal is reduced. The method can be used to treat diabetes, especially non-insulin-dependent (type II) diabetes mellitus (NIDDM) or maturity-onset diabetes mellitus.
    Type: Application
    Filed: February 14, 2001
    Publication date: March 13, 2003
    Inventors: Hamilton H. Yong, Jingming Chen