Patents by Inventor Hamish A. I. McArthur

Hamish A. I. McArthur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the purification, recovery, and sporulation of cysts and oocysts
    Patent number: 7229615
    Abstract: A vaccine for in ovo vaccination against avian coccidiosis produced by a method including obtaining the coccidial oocysts from a fecal suspension, homogenizing the fecal suspension, separating the oocysts from the fecal debris by either salt flotation using sodium sulfate or gas flotation using air, sporulating the oocysts using hydrogen peroxide and air sparging, bleaching the sporulated oocysts, washing the bleached oocysts, concentrating the sterile washed oocysts and combining the concentrates of various species of coccidial oocysts, and producing a vaccine. The method in whole or in part can be applied to other kinds of encysted protozoa to produce vaccines for various types of animals.
    Type: Grant
    Filed: October 12, 2005
    Date of Patent: June 12, 2007
    Assignee: Pfizer, Inc.
    Inventors: Harold N. Conkle, Joseph E. Schultz, Scott J. Blonigen, Fred H. Weber, David R. Kilanowski, Bruce Monzyk, Timothy M. Werner, Chad M. Cucksey, Hamish A. I. McArthur, Ted L. Tewksbury
  • Method for the purification, recovery, and sporulation of cysts and oocysts
    Patent number: 6984378
    Abstract: A vaccine for in ovo vaccination against avian coccidiosis produced by a method including obtaining the coccidial oocysts from a fecal suspension, homogenizing the fecal suspension, separating the oocysts from the fecal debris by either salt flotation using sodium sulfate or gas flotation using air, sporulating the oocysts using hydrogen peroxide and air sparging, bleaching the sporulated oocysts, washing the bleached oocysts, concentrating the sterile washed oocysts and combining the concentrates of various species of coccidial oocysts, and producing a vaccine. The method in whole or in part can be applied to other kinds of encysted protozoa to produce vaccines for various types of animals.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: January 10, 2006
    Assignee: Pfizer, Inc.
    Inventors: Harold N. Conkle, Joseph E. Schultz, Scott J. Blonigen, Fred H. Weber, David R. Kilanowski, Bruce Monzyk, Timothy M. Werner, Chad M. Cucksey, Hamish A. I. McArthur, Ted L. Tewksbury
  • Process for dienone macrolides
    Patent number: 5776735
    Abstract: The process of this invention is directed to isolating or otherwise obtaining an olefinic macrolide producing microorganism which microorganism does not contain epoxidase enzyme activity. This invention also relates to a process for preparing said olefinic macrolide by fermenting a mutant microorganism lacking epoxidase activity, designated rosX herein, which mutant is obtained from the wild-type microorganism. This invention also relates to a rosX mutant of Micromonospora rosaria, and to any microorganism having the identifying characteristics thereof, said mutant also designated ATCC 55709. This invention also relates to a process for preparing repromicin, the compound of formula (II), ##STR1## by mutating a wild-type microorganism capable of producing rosamicin to produce a mutant microorganism lacking epoxidase activity such that repromicin is produced by said mutant microorganism.
    Type: Grant
    Filed: November 6, 1996
    Date of Patent: July 7, 1998
    Assignee: Pfizer Inc.
    Inventors: Claudio D. Denoya, Edmund W. Hafner, Hamish A. I. McArthur
  • Cultures for production of avermectin aglycones
    Patent number: 5583029
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: December 10, 1996
    Assignee: Pfizer Inc.
    Inventors: Lapyuen H. Lam, Hamish A. I. McArthur, Richard G. Wax
  • Process for production of avermectin aglycones and cultures therefor
    Patent number: 5576200
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: October 14, 1994
    Date of Patent: November 19, 1996
    Assignee: Pfizer Inc.
    Inventors: Lapyuen Lam, Hamish A. I. McArthur, Richard G. Wax
  • Cultures for production of avermectin aglycones
    Patent number: 5240850
    Abstract: Mutants of Streptomyces avermitilis lacking ability to produce glycosylated avermectins and lacking branched-chain 2-oxo acid dehydrogenase activity, method for preparation thereof, and use thereof to produce natural and non-natural avermectin aglycones useful as parasiticides.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: August 31, 1993
    Assignee: Pfizer Inc.
    Inventors: Lapyuen H. Lam, Hamish A. I. McArthur, Richard G. Wax