Patents by Inventor Hamzeh AL QUBLAN

Hamzeh AL QUBLAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multivalent vaccine for protection against mycobacterial infections and methods of using the same
    Patent number: 10406219
    Abstract: Provided herein is a multivalent Brucella vaccine expressing at least one heterologous M. tuberculosis antigen. The vaccines described herein serve as an environmentally safe bivalent vaccine for protection against Brucella and Mycobacterium infections simultaneously. In particular, a multivalent vaccine comprising a Brucella strain transformed with a vector that expresses at least one M. tuberculosis antigen, where the M. tuberculosis antigen(s) is codon optimized for the Brucella strain is provided. In some aspects, the Brucella strain is B. abortus strain RB51 leuB and the M. tuberculosis antigen is one or more of Ag85B, Rv2660c, and ESAT6.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: September 10, 2019
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Sriranganathan Nammalwar, Hamzeh Al Qublan, Garrett Smith, Stephen Boyle, Gerhardt Schurig
  • MULTIVALENT BRUCELLA VACCINE FOR PROTECTION AGAINST MYCOBACTERIAL INFECTIONS AND METHODS OF USING THE SAME
    Publication number: 20170246282
    Abstract: Provided herein is a multivalent Brucella vaccine expressing at least one heterologous M. tuberculosis antigen. The vaccines described herein serve as an environmentally safe bivalent vaccine for protection against Brucella and Mycobacterium infections simultaneously. In particular, a multivalent vaccine comprising a Brucella strain transformed with a vector that expresses at least one M. tuberculosis antigen, where the M. tuberculosis antigen(s) is codon optimized for the Brucella strain is provided. In some aspects, the Brucella strain is B. abortus strain RB51 leuB and the M. tuberculosis antigen is one or more of Ag85B, Rv2660c, and ESAT6.
    Type: Application
    Filed: September 8, 2015
    Publication date: August 31, 2017
    Inventors: Sriranganathan NAMMALWAR, Hamzeh AL QUBLAN, Garrett SMITH, Stephen BOYLE, Gerhardt SCHURIG