Patents by Inventor Han-Je Kim
Han-Je Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10253033Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: November 20, 2017Date of Patent: April 9, 2019Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20180072746Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: November 20, 2017Publication date: March 15, 2018Inventors: Han-Je Kim, Jonathan S. Lindsey
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Patent number: 9822123Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: January 23, 2014Date of Patent: November 21, 2017Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20160046590Abstract: Sonic Hedgehog modulators and methods of use thereof are provided for.Type: ApplicationFiled: March 23, 2015Publication date: February 18, 2016Inventors: Sara Buhrlage, Chris Dockendorff, Mike Foley, Han-Je Kim, Andrew Germain, Lawrence MacPherson, Partha Pratim Nag, Stuart Schreiber, Amal Ting, Michel Weiwer, Willmen Youngsaye
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Publication number: 20140371286Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: January 23, 2014Publication date: December 18, 2014Applicant: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20140094462Abstract: Sonic Hedgehog modulators and methods of use thereof are provided for.Type: ApplicationFiled: February 28, 2013Publication date: April 3, 2014Inventors: Sara Buhrlage, Chris Dockendorff, Mike Foley, Han-Je Kim, Andrew Germain, Lawrence MacPherson, Partha Nag, Stuart Schreiber, Amal Ting, Michel Weiwer, Willmen Youngsaye
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Patent number: 8664260Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: April 10, 2012Date of Patent: March 4, 2014Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20120232463Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: April 10, 2012Publication date: September 13, 2012Inventors: Han-Je Kim, Jonathan S. Lindsey
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Patent number: 8173692Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: March 30, 2009Date of Patent: May 8, 2012Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Patent number: 8173691Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: March 27, 2009Date of Patent: May 8, 2012Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20090226467Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: March 30, 2009Publication date: September 10, 2009Applicant: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Publication number: 20090191130Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: March 27, 2009Publication date: July 30, 2009Inventors: Han-Je Kim, Jonathan S. Lindsey
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Patent number: 7534807Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: GrantFiled: February 17, 2006Date of Patent: May 19, 2009Assignee: North Carolina State UniversityInventors: Han-Je Kim, Jonathan S. Lindsey
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Patent number: 7408058Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.Type: GrantFiled: January 20, 2004Date of Patent: August 5, 2008Assignee: North Carolina State UniversityInventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim
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Publication number: 20060194960Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.Type: ApplicationFiled: February 17, 2006Publication date: August 31, 2006Inventors: Han-Je Kim, Jonathan Lindsey
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Publication number: 20040152887Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.Type: ApplicationFiled: January 20, 2004Publication date: August 5, 2004Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim
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Patent number: 6765092Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydroxychlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.Type: GrantFiled: December 7, 2001Date of Patent: July 20, 2004Assignee: North Carolina State UniversityInventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Man Nyoung Kim, Han-Je Kim
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Publication number: 20020137925Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydroxychlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.Type: ApplicationFiled: December 7, 2001Publication date: September 26, 2002Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim