Patents by Inventor Han-Je Kim

Han-Je Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10253033
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: April 9, 2019
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20180072746
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: November 20, 2017
    Publication date: March 15, 2018
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Patent number: 9822123
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: November 21, 2017
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20160046590
    Abstract: Sonic Hedgehog modulators and methods of use thereof are provided for.
    Type: Application
    Filed: March 23, 2015
    Publication date: February 18, 2016
    Inventors: Sara Buhrlage, Chris Dockendorff, Mike Foley, Han-Je Kim, Andrew Germain, Lawrence MacPherson, Partha Pratim Nag, Stuart Schreiber, Amal Ting, Michel Weiwer, Willmen Youngsaye
  • Publication number: 20140371286
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: January 23, 2014
    Publication date: December 18, 2014
    Applicant: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20140094462
    Abstract: Sonic Hedgehog modulators and methods of use thereof are provided for.
    Type: Application
    Filed: February 28, 2013
    Publication date: April 3, 2014
    Inventors: Sara Buhrlage, Chris Dockendorff, Mike Foley, Han-Je Kim, Andrew Germain, Lawrence MacPherson, Partha Nag, Stuart Schreiber, Amal Ting, Michel Weiwer, Willmen Youngsaye
  • Patent number: 8664260
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: April 10, 2012
    Date of Patent: March 4, 2014
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20120232463
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 13, 2012
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Patent number: 8173692
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: May 8, 2012
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Patent number: 8173691
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: May 8, 2012
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20090226467
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: March 30, 2009
    Publication date: September 10, 2009
    Applicant: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Publication number: 20090191130
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: March 27, 2009
    Publication date: July 30, 2009
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Patent number: 7534807
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: May 19, 2009
    Assignee: North Carolina State University
    Inventors: Han-Je Kim, Jonathan S. Lindsey
  • Patent number: 7408058
    Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: August 5, 2008
    Assignee: North Carolina State University
    Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim
  • Publication number: 20060194960
    Abstract: A method of making a bacteriochlorin is carried out by condensing a pair of compounds of Formula II to produce the bacteriochlorin, wherein R is an acetal or aldehyde group. The condensing may be carried out in an organic solvent, preferably in the presence of an acid. The bacteriochlorins are useful for a variety of purposes such as active agents in photodynamic therapy, luminescent compounds in flow cytometry, solar cells, light harvesting arrays, and molecular memory devices.
    Type: Application
    Filed: February 17, 2006
    Publication date: August 31, 2006
    Inventors: Han-Je Kim, Jonathan Lindsey
  • Publication number: 20040152887
    Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydronchlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.
    Type: Application
    Filed: January 20, 2004
    Publication date: August 5, 2004
    Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim
  • Patent number: 6765092
    Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydroxychlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: July 20, 2004
    Assignee: North Carolina State University
    Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Man Nyoung Kim, Han-Je Kim
  • Publication number: 20020137925
    Abstract: A method of making an oxochlorin comprises the steps of oxidizing a chlorin to produce a mixture of hydroxychlorin and oxochlorin, and then oxidizing the hydroxychlorin in said mixture, preferably with DDQ, to produce a mixture consisting essentially of oxochlorin. The step of oxidizing a chlorin is carried out by exposing the chlorin to alumina, typically in the presence of an oxidizing agent such as air or alumina. The oxidizing steps may be carried out in an organic solvent such as toluene. The chlorin is preferably a C-methylated chlorin, and is preferably metalated.
    Type: Application
    Filed: December 7, 2001
    Publication date: September 26, 2002
    Inventors: Jonathan S. Lindsey, Masahiko Taniguchi, Sreedharan Prathapan, Han-Je Kim, Man Nyoung Kim