Patents by Inventor Han-Jung LIAO

Han-Jung LIAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12048929
    Abstract: An array platform for three-dimensional cell culturing and drug testing and screening is disclosed. In the array platform, a hydrogel-cell mixture injection area is configured to inject a plurality of kinds of hydrogel-cell mixtures. Cell observation areas are connected to the hydrogel-cell mixture injection area. Electrodes are disposed under the cell observation areas and automatic cell quantification and three-dimensional cell co-arrangement of the plurality of kinds of hydrogel-cell mixtures in the cell observation areas through the electrodes to imitate a structure of body's tissues. A drug injection area is configured to inject a plurality of kinds of drugs. Drug combination generators respectively correspond to the cell observation areas and are connected to the drug injection area. Each drug combination generator has a microfluidic channel structure and configured to generate drug combinations according to the plurality of kinds of drugs.
    Type: Grant
    Filed: August 3, 2021
    Date of Patent: July 30, 2024
    Assignees: NATIONAL TSING HUA UNIVERSITY, TAIPEI MEDICAL UNIVERSITY
    Inventors: Yu-Chen Chen, Han-Jung Liao, Kang-Yun Lee, Shu-Chuan Ho, Weilun Sun, Cheng-Hsien Liu
  • Publication number: 20220395830
    Abstract: An array platform for three-dimensional cell culturing and drug testing and screening is disclosed. In the array platform, a hydrogel-cell mixture injection area is configured to inject a plurality of kinds of hydrogel-cell mixtures. Cell observation areas are connected to the hydrogel-cell mixture injection area. Electrodes are disposed under the cell observation areas and automatic cell quantification and three-dimensional cell co-arrangement of the plurality of kinds of hydrogel-cell mixtures in the cell observation areas through the electrodes to imitate a structure of body's tissues. A drug injection area is configured to inject a plurality of kinds of drugs. Drug combination generators respectively correspond to the cell observation areas and are connected to the drug injection area. Each drug combination generator has a microfluidic channel structure and configured to generate drug combinations according to the plurality of kinds of drugs.
    Type: Application
    Filed: August 3, 2021
    Publication date: December 15, 2022
    Applicants: NATIONAL TSING HUA UNIVERSITY, TAIPEI MEDICAL UNIVERSITY
    Inventors: Yu-Chen CHEN, Han-Jung LIAO, Kang-Yun LEE, Shu-Chuan HO, Weilun SUN, Cheng-Hsien LIU