Abstract: The invention provides antibodies that specifically bind to Plasminogen Activator inhibitor type-1 (PAI-1), The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-PAI-1 antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies to modulate PAI-1 activity or detect PAI-1, either in vitro or in vivo, are also provided. The disclosure further provides methods of making antibodies that specifically bind to PAI-1 in the active conformational state.

Abstract: Provided are a method for displaying a sidebar, and a terminal and a non-transitory storage medium. A first graphical user interface of a first application is displayed. A system sidebar is displayed in an edge area of a display screen of a terminal, and to-be-processed data recommended for the first application is displayed in the system sidebar. In response to a trigger operation performed on the to-be-processed data, a second graphical user interface of the first application is displayed, and the second graphical user interface is an interface for processing the to-be-processed data.

Abstract: Provided are engineered polypeptides having dehydrogenase activity that exhibit increased catalytic efficiency for nicotinamide-based unnatural cofactors relative to wild-type or parent polypeptides that encode a dehydrogenase that utilizes nicotinamide adenine dinucleotide or nicotinamide adenine dinucleotide phosphate. Also provided are cell-free and whole cell biotransformation systems for converting a substrate into a product using a redox reaction with a re-cycled unnatural cofactor that utilizes an engineered polypeptide that has dehydrogenase activity and which exhibits increased catalytic efficiency for nicotinamide-based unnatural cofactor.

Abstract: A time slot allocation processing method includes: a node device determining a time delay, in the node device, from a certain input port time slot to another port time slot, wherein the node device is a node device on an end-to-end channel; and the node device determining that the time delay is used for the establishment of end-to-end channel time slot allocation. A time delay sent by each node device is received, and end-to-end channel time slot allocation is performed according to each time delay. By using the present application, a time delay caused by time slot allocation can be reduced in a channel, thereby decreasing an end-to-end channel time delay.

Abstract: This disclosure discloses an operations, administration and maintenance (OAM) message transmission method, apparatus, sending end device, receiving end device and storage medium. The method includes: sending an OAM block by the sending end device; wherein only a single OAM block is sent in each sending period.

Abstract: The present disclosure provides monoclonal and recombinant anti-CDH17 antibodies (including CDH17 biparatopic and CDH17xCD3 bispecific antibodies and CDH17-binding fragments. Such antibodies and binding fragments are useful for the treatment of cancer, cither alone or in combination with other agents.

Abstract: An electrical appliance monitoring system and an electrical appliance monitoring method are provided. The electrical appliance monitoring system comprises a processor and a storage circuit. The processor is electrically connected to the storage circuit. The storage circuit stores a power consumption data model and on-off state identification models. The processor executes the power consumption data model to output power timing records according to the total power timing data. The processor extracts characteristic waveforms from the power consumption data model. The processor executes the on-off state identification models. Each on-off state identification model outputs the on-off state identification timing records according to the characteristic waveforms. The processor outputs on-off state timing data for each electrical appliance according to the on-off state identification timing records outputted by the on-off state identification models.

Abstract: A communication device includes: one or more voltage conversion circuits. The one or more voltage conversion circuits are separately coupled to a power supply of the communication device. A voltage sampling circuit is coupled to the power supply, and/or the voltage sampling circuit is coupled to an output end of at least one of the one or more voltage conversion circuits. A controller is configured to: control the voltage sampling circuit to collect voltages output by the power supply or voltages output by a first voltage conversion circuit in a plurality of sending timeslots or a plurality of receiving timeslots of the communication device; and determine a real voltage of the power supply based on the voltages output by the power supply or the voltages output by the first voltage conversion circuit in the plurality of sending timeslots or the plurality of receiving timeslots of the communication device.

Abstract: The present disclosure provides a distributed phase-shifting transforming apparatus, including N transformer rectifier units, where each transformer rectifier unit includes two three-phase three-winding transformers and four rectifier circuits, each three-phase three-winding transformer includes first windings on the primary side and second windings and third windings on the secondary side, AC power output by the second windings and the third windings on the secondary side is output after being rectified by the rectifier circuits. Each transformer rectifier unit is configured such that: one set of the two first windings on the primary side and the two second windings on the secondary side is phase-shifted by 15° from each other, and the other set has the same phase angle; and the second windings and the third windings of each three-phase three-winding transformer are phase-shifted by 30° from each other.

Abstract: A split screen method, an electronic device, and a storage medium are disclosed. The method includes: in response to a two-finger sliding operation acting on a touch screen, obtaining a sliding direction corresponding to the two-finger sliding operation; and splitting a displayable area into a first split screen area and a second split screen area based on the sliding direction, one of the first split screen area and the second split screen area is used to display a multi-task interface. In this way, split screen operation steps are simplified to improve a split screen speed.

Abstract: The invention provides antibodies that specifically bind to Kallidin or des-Arg10-Kallidin. The invention also provides pharmaceutical compositions, as well as nucleic acids encoding anti-Kallidin or des-Arg10-Kallidin antibodies, recombinant expression vectors and host cells for making such antibodies, or fragments thereof. Methods of using antibodies of the invention to modulate Kallidin or des-Arg10-Kallidin activity or detect Kallidin or des-Arg10-Kallidin or, either in vitro or in vivo, are also provided by the invention. The invention further provides methods of making antibodies that specifically bind to des-Arg9-Bradykinin and des-Arg10-Kallidin-like peptide.

Abstract: An online system accesses a two-tower model trained to identify candidate items for presentation to users, in which the model includes an item tower trained to compute item embeddings and a user tower trained to compute user embeddings. The user tower includes a long-term sub-tower trained to compute long-term embeddings for users and a short-term sub-tower trained to compute short-term embeddings for users. The model is trained based on item data associated with items, user data associated with users, and session data associated with user sessions. The system uses the item tower to compute an item embedding for each of multiple candidate items. The system also uses the long-term sub-tower to compute a long-term embedding for a user. The system then receives session data associated with a current session of the user and uses the short-term sub-tower to compute a short-term embedding for the user based on this session data.

Abstract: According to embodiments of the disclosure, a method, an apparatus, a device, and a storage medium for prompt determination are provided. The method includes: presenting, in response to receiving a first interaction request for specifying a type of a task to be performed, an interaction area matching the type, the interaction area including: a data input box for inputting data to be processed; and a prompt template matching the type, the prompt template specifying a plurality of attributes of a prompt for performing the task; and generating, in response to receiving a second interaction request for the interaction area, the prompt for performing the task.

Abstract: Disclosed is a multi-view fusion human motion estimation method based on distributed progressive Gaussian filtering. Firstly, data acquisition is performed by means of two Azure Kinect DK cameras and initial data is determined; then, data filtering and fusion processing is performed, the initial data of the two Azure Kinect DK cameras is classified and processed by using Mahalanobis distance, the measurement information of the Azure Kinect DK cameras that are greatly affected by visual occlusion is filtered out and discarded, and the measurement information of one Azure Kinect DK camera that is determined to be less affected by visual occlusion is guided by the measurement information of the other Azure Kinect DK camera to undergo progressive filtering fusion, thereby achieving the effect of implicit compensation; finally, global fusion is performed, thereby improving the accuracy of human pose estimation.

Abstract: A speech control system includes a first client running on a mobile terminal, a server end running on a server, and a second client running on a controlled terminal. The first client obtains identity information of a user, and sends the identity information of the user to the server end. The server end verifies the identity information of the user. The first client further collects speech data of the user, generates a speech control request based on the speech data, and sends the speech control request to the server end. When verification on the identity information succeeds, the server end generates a control instruction based on the speech control request, and sends the control instruction to the second client. The second client indicates the controlled terminal to execute the control instruction.

Abstract: A mapping method includes: inserting a first indication and/or a second indication into an overhead area of a first frame. The first indication is configured to indicate adjusting a rate of the first frame, and the second indication is configured to indicate adjusting the rate of the first frame from a first rate to a second rate.

Abstract: A method and apparatus for displaying an application interface, and a terminal and a storage medium, which relate to the technical field of human-computer interaction. The method comprises: when a terminal with a foldable screen is in an unfolded state, displaying, in a first screen area, a target application interface of a target application program; when the terminal with a foldable screen is switched from the unfolded state to a folded state, stopping displaying the target application interface in the first screen area, and displaying, in a second screen area, a shortcut application icon of the target application program, wherein a display mode of the shortcut application icon is different from a display mode of a default application icon of the target application program; and in response to a trigger operation for the shortcut application icon, displaying the target application interface in the second screen area.

Abstract: A security management system includes a first server. The first server is configured to: obtain access information of a terminal device; generate, if the access information of the terminal device meets an access condition, a first key based on a registration time of the terminal device, identification information of the terminal device, and fingerprint information of the terminal device; encrypt the first key using a second key, the first key being different from the second key; and send the encrypted first key to the terminal device, so that the terminal device decrypts the encrypted first key using the second key.

Abstract: According to embodiments of the disclosure, a method, an apparatus, a device, and a storage medium for prompt determination are provided. The method includes: presenting, in response to receiving a first interaction request for specifying a type of a task to be performed, an interaction area matching the type, the interaction area including: a data input box for inputting data to be processed; and a prompt template matching the type, the prompt template specifying a plurality of attributes of a prompt for performing the task; and generating, in response to receiving a second interaction request for the interaction area, the prompt for performing the task.

Abstract: A camera system includes a camera, a privacy indicator configured to indicate an activation status of the camera, and an optical camera blocker disposed between the camera and an external environment. The optical camera blocker is configured to, when activated, obscure images captured by the camera. A privacy control circuit is configured to compare a state of a first circuit trace indicative of an intended operational status of the privacy indicator with a state of a second circuit trace indicative of an actual operational status of the privacy indicator, and based at least in part on detecting a mismatch between the state of the first circuit trace and the state of the second circuit trace, activate the optical camera blocker.