Abstract: The present invention provides a biosensor and an application of the same. The biosensor includes a substrate, a first polymer layer and a second polymer layer. The first polymer layer includes composite antibodies, each of which includes a first antibody and a labelling molecule. The second polymer layer has an inverse opal photonic crystal structure where gold nanoparticles and second antibodies are distributed. At least one of the composite antibodies, an antigen and at least one of the second antibodies forms a complex in the second polymer layer, and an antigen concentration is obtained by a fluorescence intensity, a degree of red-shift or a change in a visual color of the biosensor.

Abstract: A method for detecting an analyte concentration of the present invention includes performing a competitive reaction between a first complex and an analyte standard or an analyte sample, so that the first complex may combine with a metal nanoparticle, and a second complex of a control group and a third complex of a sample group are respectively formed. Then, a difference of heat diffusivity of the second complex and the third complex may determine an analyte sample concentration of the sample group is higher or lower than a pre-determined analyte standard concentration of the control group.

Abstract: The present invention provides a biosensor and an application of the same. The biosensor includes a substrate, a first polymer layer and a second polymer layer. The first polymer layer includes composite antibodies, each of which includes a first antibody and a labelling molecule. The second polymer layer has an inverse opal photonic crystal structure where gold nanoparticles and second antibodies are distributed. At least one of the composite antibodies, an antigen and at least one of the second antibodies forms a complex in the second polymer layer, and an antigen concentration is obtained by a fluorescence intensity, a degree of red-shift or a change in a visual color of the biosensor.

Abstract: A method for detecting an analyte concentration of the present invention includes performing a competitive reaction between a first complex and an analyte standard or an analyte sample, so that the first complex may combine with a metal nanoparticle, and a second complex of a control group and a third complex of a sample group are respectively formed. Then, a difference of heat diffusivity of the second complex and the third complex may determine an analyte sample concentration of the sample group is higher or lower than a pre-determined analyte standard concentration of the control group.

Abstract: A microfluidic arrangement including a fluid channel configured to receive a first fluid from a first inlet and a second fluid from a second inlet, and a mixer connected to the fluid channel, the mixer including a mixer channel configured to receive a volume of the first fluid and a volume of the second fluid from the fluid channel, the mixer channel defining a mixer capacity, wherein the mixer is (i) configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is less than the mixer capacity, and (ii) further configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is equal to the mixer capacity.

Abstract: The present invention relates to a method and a device for measuring liquid viscosity based on Brownian movements of particles suspended in a fluid.

Abstract: An open optoelectrowetting (o-OEW) device for liquid droplet manipulations. The o-OEW device is realized by coplanar electrodes and a photoconductor. The local switching effect for electrowetting resulting from illumination is based on the tunable impedance of the photoconductor. Dynamic virtual electrodes are created using projected images, leading to free planar movements of droplets.

Abstract: A microfluidic purge valve in a microfluidics system includes a notch defined in the valve seat of a microfluidic valve. The notch is sized so that gas entrained within a liquid pumped through the microfluidics system can pass freely therethrough but the liquid cannot. The notch is sized so that the resistant force generated by the surface tension of the liquid is equal to or greater than the force generated by the fluid pressure.

Abstract: A microfluidic arrangement including a fluid channel configured to receive a first fluid from a first inlet and a second fluid from a second inlet, and a mixer connected to the fluid channel, the mixer including a mixer channel configured to receive a volume of the first fluid and a volume of the second fluid from the fluid channel, the mixer channel defining a mixer capacity, wherein the mixer is (i) configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is less than the mixer capacity, and (ii) further configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is equal to the mixer capacity.

Abstract: An open optoelectrowetting (o-OEW) device for liquid droplet manipulations. The o-OEW device is realized by coplanar electrodes and a photoconductor. The local switching effect for electrowetting resulting from illumination is based on the tunable impedance of the photoconductor. Dynamic virtual electrodes are created using projected images, leading to free planar movements of droplets.

Abstract: A microfluidic purge valve in a microfluidics system includes a notch defined in the valve seat of a microfluidic valve. The notch is sized so that gas entrained within a liquid pumped through the microfluidics system can pass freely therethrough but the liquid cannot. The notch is sized so that the resistant force generated by the surface tension of the liquid is equal to or greater than the force generated by the fluid pressure.

Abstract: A device for measuring a flow of a fluid is provided. The device includes a base, a channel, and at least two electronic circuits. The channel is mounted on the base, flowing the fluid therein and having at least two sections, and the at least two electronic circuits are electrically connected to the respective at least two sections, detecting a respective variation signal corresponding to the respective at least two sections so as to obtain the flow according to the respective variation signal.

Abstract: A device for measuring a flow of a fluid is provided. The device includes a base, a channel, and at least two electronic circuits. The channel is mounted on the base, flowing the fluid therein and having at least two sections, and the at least two electronic circuits are electrically connected to the respective at least two sections, detecting a respective variation signal corresponding to the respective at least two sections so as to obtain the flow according to the respective variation signal.

Abstract: A micro droplet controlling apparatus. A dielectric layer is disposed overlying a substrate. A first electrode and a second electrode are disposed in the dielectric layer, wherein the first electrode is isolated from the second electrode, and the first and second electrodes are disposed at different positions. A micro droplet is disposed overlying the dielectric layer, wherein the first electrode and the second electrode are applied with voltage to generate a driving force to move the micro droplet.