Patents by Inventor Han Won Lee

Han Won Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9890404
    Abstract: The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: February 13, 2018
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
  • Patent number: 9834491
    Abstract: The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence of an acid catalyst. According to the present invention, O-acyl homoserine produced by a microorganism is used as a raw material for producing 1,4-butanediol, gamma-butyrolactone, tetrahydrofuran and the like, which are industrially highly useful. The O-acyl homoserine produced by a microorganism can substitute conventional petrochemical products, can solve environmental concerns, including the emission of pollutants and the exhaustion of natural resources, and can be continuously renewable so as not to exhaust natural resources.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: December 5, 2017
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Han Won Lee, Young Lyeol Yang, So Young Kim, Yong Uk Shin, Jin Sook Chang, Hye Won Um, Young Hyoung Goh, Sung Hoo Jhon
  • Patent number: 9303277
    Abstract: The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: April 5, 2016
    Assignee: CJ CHEILJEDANG CORPORATION
    Inventors: Hyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
  • Patent number: 8927774
    Abstract: The present invention relates to a method for separating and purifying 1,4-diaminobutane at high purity and high yield from a fermented solution comprising 1,4-diaminobutane, through cell mass removement, desalination, concentration, impurities removal, and recovery. Also, provided is a method for separating and purifying 1,4-diaminobutane at high purity and high yield from a fermented solution 1,4-diaminobutane, through cell mass removement, desalination, low-temperature concentration, crystallization, filtration, high-temperature concentration and distillation.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: January 6, 2015
    Assignee: CJ Cheiljedang Corporation
    Inventors: Won Sik Gwak, Soon Won Hong, Soo An Shin, Han Won Lee
  • Publication number: 20140296466
    Abstract: The present invention relates to a method of producing bio-based homoserine lactone and bio-based organic acid through hydrolysis of O-acyl homoserine produced by a microorganism in the presence of an acid catalyst. According to the present invention, O-acyl homoserine produced by a microorganism is used as a raw material for producing 1,4-butanediol, gamma-butyrolactone, tetrahydrofuran and the like, which are industrially highly useful. The O-acyl homoserine produced by a microorganism can substitute conventional petrochemical products, can solve environmental concerns, including the emission of pollutants and the exhaustion of natural resources, and can be continuously renewable so as not to exhaust natural resources.
    Type: Application
    Filed: March 19, 2014
    Publication date: October 2, 2014
    Inventors: Han Won Lee, Young Lyeol Yang, So Young Kim, Yong Uk Shin, Jin Sook Chang, Hye Won Um, Young Hyoung Goh, Sung Hoo Jhon
  • Publication number: 20140213824
    Abstract: The present invention relates to a method for separating and purifying 1,4-diaminobutane at high purity and high yield from a fermented solution comprising 1,4-diaminobutane, through cell mass removement, desalination, concentration, impurities removal, and recovery. Also, provided is a method for separating and purifying 1,4-diaminobutane at high purity and high yield from a fermented solution 1,4-diaminobutane, through cell mass removement, desalination, low-temperature concentration, crystallization, filtration, high-temperature concentration and distillation.
    Type: Application
    Filed: August 24, 2012
    Publication date: July 31, 2014
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Won Sik Gwak, Soon Won Hong, Soo An Shin, Han Won Lee
  • Publication number: 20140004577
    Abstract: The present invention relates to a putrescine-producing microorganism and a method for producing putrescine using the same. To be more specific, the present invention is directed to a microorganism given the ability to produce putrescine which is generated by blocking a biosynthetic pathway from ornithine to arginine, increasing the intracellular level of glutamate, enhancing the biosynthetic pathway of ornithine from glutamate, and introducing extracellular ornithine decarboxylase; and a method for producing putrescine by using the microorganism.
    Type: Application
    Filed: December 8, 2011
    Publication date: January 2, 2014
    Applicant: CJ CHEILJEDANG CORPORATION
    Inventors: Hyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
  • Publication number: 20130344545
    Abstract: The present invention relates to a microorganism having an improved ornithine-producing ability, in which the biosynthetic pathway of arginine form ornithine is blocked, the intracellular glutamate level is increased, and the biosynthetic pathway of ornithine from glutamate is enhanced, and a method for producing ornithine using the microorganism.
    Type: Application
    Filed: December 8, 2011
    Publication date: December 26, 2013
    Applicant: CJ CHELJEDANG CORPORATION
    Inventors: Hyang Choi, Kyoung Min Lee, Min Sun Kang, Sung Hoo Jhon, Hye Won Um, Su Jin Choi, Han Won Lee, Soo An Shin
  • Patent number: 6143900
    Abstract: The present invention relates to stereoselective synthetic method of oxazoline derivative. More particularly, it relates to a synthetic method of oxazoline derivative having the structure of formula I. ##STR1## wherein R represents phenyl, benzyl, methyl, ethyl, isopropyl, isobutyl, cyclohexyl or cyclohexylmethyl.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: November 7, 2000
    Assignee: Dong Kook Pharmaceutical Co., Ltd.
    Inventors: Won Hun Ham, Kyung Seok Choi, Han Won Lee, Sung Ki Seo, Jin Kyu Park, Ki Young Lee, Yong Hyun Kim
  • Patent number: 6127546
    Abstract: The present invention relates to a process for the preparation of an oxazoline compound which is easily chemically converted to a beta-amino-alpha-hydroxy acid or a gamma-amino-beta-hydroxy acid. The method comprises producing a compound of the following formula (4) using .alpha.-amino acid. The produced compound (4) is subjected to an intramolecular cyclization to produce an oxazoline compound of the following formula (3). The oxazoline compound (3) is oxidized at a vinyl group with RuCl.sub.3 or NaIO.sub.4 to produce an oxazoline compound of the following formula (1) which is easily chemically converted to a beta-amino-alpha-hydroxy acid. Alternatively, the oxazoline compound (3) may also be treated with 9-borabiclo[3.3.1]nonane such that a hydroxy group is introduced into the end of the vinyl group of the oxazoline compound(3). The introduced end hydroxy group is oxidized with RuCl.sub.3 or NaIO.sub.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: October 3, 2000
    Assignee: Dong Kook Pharmaceutical Co., Ltd.
    Inventors: Jin Kyu Park, Kyung Seok Choi, Han Won Lee, Sung Ki Seo, Won Hun Ham, Chang Young Oh, Kee Young Lee, Yong Hyun Kim, Min Sung Park