Patents by Inventor Han Zou

Han Zou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180318496
    Abstract: A drug delivery device (50) is provided comprising a drug reservoir (10) and a piston (11). The drug reservoir (10) is provided for comprising a drug and comprises a flexible wall (22) and a dispensing hole (15) for dispensing the drug into an environment of the drug delivery device (50). The piston (11) is provide for pressing against the flexible wall (22) to compress the drug reservoir (10) for pushing an amount of the drug through the dispensing hole (15). An adhesion interface (51) between a surface of the piston (11) and the flexible wall (22) prevents sliding between the surface of the piston (11) and the flexible wall (22).
    Type: Application
    Filed: July 13, 2018
    Publication date: November 8, 2018
    Applicant: Progenity, Inc.
    Inventors: Hans Zou, Jeff Shimizu, Johan Frederik Dijksman
  • Patent number: 10116216
    Abstract: An embodiment of a buck-boost power converter may include an inductor driver section configured to control four switches to control an output of the converter, and a PWM circuit to generate a PWM control signal responsive to an output level of the output. An embodiment of a switch control is configured to, when an on time of the second switch becomes less than a specified entry value, force the third switch to generate boot refreshing pulses with an on time of a specified duration value at a rate more than a specified frequency, and when an on time of the third switch becomes less than the specified entry value, force the second switch to generate boot refreshing pulses with an on time of the specified duration value at the rate more than the specified frequency.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: October 30, 2018
    Assignee: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Jinseok Park, Han Zou, Kedar Bharat Patel
  • Publication number: 20180271752
    Abstract: A system for administering a medicament includes a plurality of capsules, a capsule dispenser, and a capsule activator. Each of the capsules includes a reservoir containing a medicament and an outlet in communication with the reservoir through which the medicament exits the capsule. The capsule dispenser releasably contains the ingestible capsules and is adapted to dispense the capsules to a user in accordance with a predetermined schedule. The capsule activator activates the dispensed capsules prior to administration to the user.
    Type: Application
    Filed: February 2, 2018
    Publication date: September 27, 2018
    Inventors: Ventzeslav Petrov Iordanov, Hans Zou, Christoph Wanke, Klaas Kerkhof, Jeffrey A. Shimizu
  • Patent number: 10046109
    Abstract: A drug delivery device (50) is provided comprising a drug reservoir (10) and a piston (11). The drug reservoir (10) is provided for comprising a drug and comprises a flexible wall (22) and a dispensing hole (15) for dispensing the drug into an environment of the drug de delivery device (50). The piston (11) is provide for pressing against the flexible wall (22) to compress the drug reservoir (10) for pushing an amount of the drug through the dispensing hole (15). An adhesion interface (51) between a surface of the piston (11) and the flexible wall (22) prevents sliding between the surface of the piston (11) and the flexible wall (22).
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: August 14, 2018
    Assignee: Progenity, Inc.
    Inventors: Hans Zou, Jeff Shimizu, Johan Frederik Dijksman
  • Publication number: 20180200426
    Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.
    Type: Application
    Filed: January 25, 2018
    Publication date: July 19, 2018
    Inventors: JOHAN FREDERIK DIJKSMAN, FRITS TOBI DE JONGH, MICHEL GERARDUS PARDOEL, ANKE PIERIK, JUDITH MARGREET RENSEN, JEFF SHIMIZU, HANS ZOU, REMUS ALBU, VENTZESLAV IORDANOV, HANS MARC BERT BOEVE
  • Patent number: 9918904
    Abstract: A system for administering a medicament includes a plurality of capsules, a capsule dispenser, and a capsule activator. Each of the capsules includes a reservoir containing a medicament and an outlet in communication with the reservoir through which the medicament exits the capsule. The capsule dispenser releasably contains the ingestible capsules and is adapted to dispense the capsules to a user in accordance with a predetermined schedule. The capsule activator activates the dispensed capsules prior to administration to the user.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: March 20, 2018
    Assignee: Stoco 10 GmbH
    Inventors: Ventzeslav Petrov Iordanov, Hans Zou, Christoph Wanke, Klaas Kerkhop, Jeffrey A. Shimizu
  • Patent number: 9878094
    Abstract: A medicament delivery device, which comprises a driving mechanism and a housing (1) having a reservoir (2), which is at least partly filled with a substance and which is sealed at least on one side with a flexible wall (21). The driving mechanism is adapted to press a piston (23) against the flexible wall (21) thereby releasing the substance from the reservoir (2) through an opening (25) in the reservoir (2). This provides for a safe and reliable medicament delivery device.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: January 30, 2018
    Assignee: STOCO 10 GMBH
    Inventors: Johan Frederik Dijksman, Frits Tobi De Jongh, Michel Gerardus Pardoel, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Remus Albu, Ventzeslav Iordanov, Hans Marc Bert Boeve
  • Publication number: 20170288550
    Abstract: A buck-boost power converter includes an inductor driver section, a pulse width modulated (PWM) section, and a switch control section. The inductor driver includes a first switch to selectively couple an input to a first node of an inductor, a second switch to selectively couple the first node of the inductor to a ground node, a third switch to selectively couple a second node of the inductor to the ground node, and a fourth switch to selectively couple the second node of the inductor to an output, and a pulse width modulated (PWM) to generate a PWM control signal responsive to an output level of the output.
    Type: Application
    Filed: March 29, 2016
    Publication date: October 5, 2017
    Applicant: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Jinseok PARK, Han ZOU, Kedar Bharat PATEL
  • Patent number: 9744139
    Abstract: An ingestible capsule (10) is provided for delivery of a drug, the capsule (10) comprises a first module (11) and a second module (12). The first module (11) has at least one drug compartment (13) for comprising an amount of the drug. The drug compartment (13) is sealed by a foil (14) with an embedded conducting heating wire (15). The second (12) module comprises electronics (18) for providing an electrical pulse to the heating wire (15) in order to open the drug compartment (13) by melting the foil (14). The first module (11) and second module (12) comprise interoperable connection means (19) for securing the first module (11) to the second module (12) such that the heating wire (15) is electronically coupled to the electronics (18).
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: August 29, 2017
    Assignee: Stoco 10 GmbH
    Inventors: Johan Frederik Dijksman, Anke Pierik, Frits Tobi De Jongh, Jeff Shimizu, Hans Zou, Lucian Remus Albu, Olaf Weiner
  • Patent number: 9687638
    Abstract: The invention relates to a swallowable medication capsule capable 200 of dispensing fluid medicine stored in a medication compartment 211 through a valveless exit hole 207. A vent hole 206 enables ventilation of an actuator cavity 212 which houses an actuator used for displacing a surface 205 which separates the medication cavity 211 and the actuator cavity 212. By locating the vent and exit holes close to each other so that contact with contracting parts of the gastrointestinal tract and the exterior surface 221 is not able to prohibit a pressure passageway between the vent and exit holes, creation of a pressure difference of pressures in the medication and actuator cavity is prohibited.
    Type: Grant
    Filed: March 23, 2012
    Date of Patent: June 27, 2017
    Assignee: Medimetrics Personalized Drug Delivery
    Inventors: Hans Zou, Jeff Shimizu
  • Patent number: 9616206
    Abstract: The invention relates to an electronic pill (102) for delivery of a medication (104) inside a mammal. The electronic pill (102) comprises a reservoir (106) for releasing the medication (104) in response to a predefined level of pressure. Furthermore a primary elastic element (108) is comprised for applying said predefined level of pressure to the reservoir (106) via a piston (110) upon release from the piston (110) of its constrained position. The piston (110) in its turn, when in constrained position, induces a predefined level of stress in the primary elastic element (108) by accordingly deforming it. The electronic pill (102) comprises a mechanism (114) for changing, upon actuation, from a constraining configuration in which the piston (110) is maintained at its constrained position to a releasing configuration in which the piston (110) is released.
    Type: Grant
    Filed: September 29, 2011
    Date of Patent: April 11, 2017
    Assignee: Medimetrics Personalized Drug Delivery
    Inventors: Michel Gerardus Pardoel, Hans Zou, Jeff Shimizu
  • Patent number: 9550050
    Abstract: An electronic capsule (100) is provided. The capsule (100) has a discrete drive element (300) comprising: a housing (109), electronics for making the electronic capsule (100) operable, a pumping mechanism (115) for dosing and displacing a substance, a power source (105) for powering the electronic capsule (100) and enabling the electronics and the pumping mechanism (115) to operate, and a locking mechanism (130); and a discrete payload element (200) comprising: a housing (109), a reservoir (210) for storing the substance, one or more openings (250) in the housing (109) for releasing the substance from the reservoir (210) and a locking mechanism (230) for engaging the drive element locking mechanism (130). Engagement of the drive element locking mechanism (130) with the payload element locking mechanism (230) secures the drive element (300) to the payload element (200), thereby making the electronic capsule (100) operable and specific.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: January 24, 2017
    Assignee: Medimetrics Personalized Drug Delivery B.V.
    Inventors: Johan Frederik Dijksman, Anke Pierik, Judith Margreet Rensen, Jeff Shimizu, Hans Zou, Michel Pardoel, Frits Tobi De Jongh
  • Publication number: 20160235663
    Abstract: A capsule includes a compressible reservoir and a gas generating unit disposed in a housing. A threshold valve seals an opening in the housing, through which contents of the reservoir may exit the capsule. Gas generated by the gas generating unit increases pressure in the capsule, thereby compressing the reservoir. When a pressure acting on the threshold valve reaches a threshold pressure, the threshold valve opens, releasing contents of the reservoir.
    Type: Application
    Filed: September 25, 2014
    Publication date: August 18, 2016
    Inventors: Hans Zou, Jeffrey A. Shimizu, Ventzeslav Petrov Iordanov, Klaas Kerkhof, Christoph Wanke
  • Patent number: 9325194
    Abstract: In one embodiment, a power supply controller may be formed including configuring the power supply controller to use an error signal and a ramp signal to control a duty cycle of a switching control signal that is configured to control first and second switches to charge a battery, and configuring the power supply controller to selectively offset a dc value of the ramp signal responsively to detecting the adapter current is greater than a first value wherein offsetting the dc value of the ramp signal changes the duty cycle of the switching control signal to supply current from the battery to a load.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: April 26, 2016
    Assignee: SEMICONDUCTOR COMPONENTS INDUSTRIES, LLC
    Inventors: Han Zou, Thomas Duffy, Eduardo Velarde
  • Patent number: 9236076
    Abstract: A perpendicular magnetic recording disk includes a template layer below a Ru or Ru alloy underlayer, with a granular Co alloy recording layer formed on the underlayer. substrate. The template layer comprises nanoparticles spaced-apart and partially embedded within a polymer material, with the nanoparticles protruding above the surface of the polymer material. A seed layer covers the surface of the polymer material and the protruding nanoparticles and an underlayer of Ru or a Ru alloy covers the seed layer. The protruding nanoparticles serve as the controlled nucleation sites for the Ru or Ru alloy atoms. The nanoparticle-to-nanoparticle distances can be controlled during the formation of the template layer. This enables control of the Co alloy grain diameter distribution as well as grain-to-grain distance distribution.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: January 12, 2016
    Assignee: HGST Netherlands B.V.
    Inventors: Bruce Alvin Gurney, Ricardo Ruiz, Manfred Ernst Schabes, Kentaro Takano, Shi-Ling Chang Wang, Qing Zhu, Han Zou
  • Patent number: 9227011
    Abstract: A sensor comprising a plurality of electrodes having a miniature size and a lower power consumption and a coating exterior to the electrodes, wherein the coating interacts with a target condition thereby producing a change in an electrical property of the electrodes, wherein the change is transduced into an electrical signal by the electrodes. Further a system for medication delivery comprising such sensor and a pill.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: January 5, 2016
    Assignee: Medimetrics Personalized Drug Delivery B.V.
    Inventors: Jeff Shimizu, Hans Zou, Johan Frederik Dijksman, Anke Pierik, Judith Margaret Rensen
  • Patent number: 9224412
    Abstract: A continuous-media perpendicular magnetic recording disk has a granular recording layer (RL) with controlled grain pitch distribution and controlled long range ordering of the grains. The disk includes a substrate with a template layer for the RL that comprises a blend of at least two different sized nanoparticles. The nanoparticles have a nanoparticle core with attached polymer ligands. The nanoparticle cores protrude above the surface of the template layer to provide a nonplanar surface topology. The blend of two sizes of nanoparticles causes the RL to have low grain pitch distribution and a disruption of long range ordering so that there are no large magnetic rafts. One of the nanoparticles types has a diameter greater than 105% of the diameter of the other nanoparticle type and is present in the total blend of nanoparticles of between about 5% and 35% or between about 55% and 90%.
    Type: Grant
    Filed: January 31, 2014
    Date of Patent: December 29, 2015
    Assignee: HGST Netherlands B.V.
    Inventors: Bruce Alvin Gurney, Ricardo Ruiz, Shi-Ling Chang Wang, Qing Zhu, Han Zou
  • Publication number: 20150272830
    Abstract: A system for administering a medicament includes a plurality of capsules, a capsule dispenser, and a capsule activator. Each of the capsules includes a reservoir containing a medicament and an outlet in communication with the reservoir through which the medicament exits the capsule. The capsule dispenser releasably contains the ingestible capsules and is adapted to dispense the capsules to a user in accordance with a predetermined schedule. The capsule activator activates the dispensed capsules prior to administration to the user.
    Type: Application
    Filed: September 23, 2013
    Publication date: October 1, 2015
    Inventors: Ventzeslav Petrov Iordanov, Hans Zou, Christoph Wanke, Klaas Kerkhop, Jeffrey A. Shimizu
  • Publication number: 20150221330
    Abstract: A continuous-media perpendicular magnetic recording disk has a granular recording layer (RL) with controlled grain pitch distribution and controlled long range ordering of the grains. The disk includes a substrate with a template layer for the RL that comprises a blend of at least two different sized nanoparticles. The nanoparticles have a nanoparticle core with attached polymer ligands. The nanoparticle cores protrude above the surface of the template layer to provide a nonplanar surface topology. The blend of two sizes of nanoparticles causes the RL to have low grain pitch distribution and a disruption of long range ordering so that there are no large magnetic rafts. One of the nanoparticles types has a diameter greater than 105% of the diameter of the other nanoparticle type and is present in the total blend of nanoparticles of between about 5% and 35% or between about 55% and 90%.
    Type: Application
    Filed: January 31, 2014
    Publication date: August 6, 2015
    Applicant: HGST Netherlands B.V.
    Inventors: Bruce Alvin Gurney, Ricardo Ruiz, Shi-Ling Chang Wang, Qing Zhu, Han Zou
  • Patent number: 9067011
    Abstract: A device for placement in an environment, particularly a humid environment, for delivery of medication to said environment. The device comprises a reservoir (103) having an orifice (104), a conveying unit for conveying a reservoir's content (106) through the orifice (104) and an actuator arrangement for driving the conveying unit. In order to provide a reliable delivery of medication in a humid environment, the conveying unit comprises an auger (110) extending in the reservoir (103).
    Type: Grant
    Filed: June 17, 2009
    Date of Patent: June 30, 2015
    Assignee: Medimetrics Personalized Drug Delivery B.V.
    Inventors: Hans Zou, Jeff Shimizu, Lucian R. Albu, Johan F. Dijksman