Patents by Inventor Hana Dvorakova

Hana Dvorakova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiretroviral enantiomeric nucleotide analogs
    Patent number: 6653296
    Abstract: Resolved enantiomers of the formula (IA) and (IB) wherein B is a purine or pyrimidine base or aza and/or deaza analogs thereof are useful in antiviral pharmaceutical compositions to treat retroviral infections.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: November 25, 2003
    Assignees: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting v.z.w.
    Inventors: Antonin Holy, Hana Dvorakova, Erik Desire Alice De Clercq, Jan Marie Rene Balzarini
  • Antiretroviral enantiomeric nucleotide analogs
    Patent number: 6057305
    Abstract: Resolved enantiomers of the formula ##STR1## wherein B is a purine or pyrimidine base or aza and/or deaza analogs thereof are useful in antiviral pharmaceutical compositions to treat retroviral infections.
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: May 2, 2000
    Assignees: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic, Rega Stichting, v.z.w.
    Inventors: Antonin Holy, Hana Dvorakova, Erik Desire Alice DeClercq, Jan Marie Rene Balzarini
  • (2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-to luenesulfonyloxy-1-trimethylacetoxypropane, its preparation and use
    Patent number: 5130427
    Abstract: The invention relates to the new compound (2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-toluenesulfonyloxy-1-trimethyla cetoxypropane and the method of producing it. The compound may be used for producing (S)-N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of the heterocyclic purine and pyrimidine bases of antiviral activity.
    Type: Grant
    Filed: July 12, 1991
    Date of Patent: July 14, 1992
    Assignee: Ceskoslovenska akademie ved
    Inventors: Petr Alexander, Antonin Holy, Hana Dvorakova
  • (2R)-2-[di(2-propyl)phosphonyylmethoxy]-3-P-tolue nesulfonyloxy-1-trimethylacetoxypropane, its preparation and use
    Patent number: RE35558
    Abstract: The invention relates to the new compound (2R)-2-[di(2-propyl)phosphonylmethoxy]-3-p-toluenesulfonyloxy-1-trimethyla cetoxypropane and the method of producing it. The compound may be used for producing (S)-N-(3-hydroxy-2-phosphonylmethoxypropyl) derivatives of the heterocyclic purine and pyrimidine bases of antiviral activity.
    Type: Grant
    Filed: July 14, 1994
    Date of Patent: July 8, 1997
    Assignee: Institute of Organic Chemistry and Biochemistry of the Academy of Sciences of the Czech Republic
    Inventors: Petr Alexander, Antonin Holy, Hana Dvorakova