Patents by Inventor Hanadie Yousef

Hanadie Yousef has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10214725
    Abstract: Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: February 26, 2019
    Assignee: The Regents of The University of California
    Inventors: Irina M. Conboy, Michael J. Conboy, Hanadie Yousef, David V. Schaffer
  • Publication number: 20180155683
    Abstract: Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition.
    Type: Application
    Filed: August 8, 2017
    Publication date: June 7, 2018
    Inventors: Irina M. Conboy, Michael J. Conboy, Hanadie Yousef, David V. Schaffer
  • Patent number: 9758763
    Abstract: Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition.
    Type: Grant
    Filed: May 27, 2014
    Date of Patent: September 12, 2017
    Assignee: The Regents of the University of California
    Inventors: Irina M. Conboy, Michael J. Conboy, Hanadie Yousef, David V. Schaffer
  • Publication number: 20170239320
    Abstract: Methods, pharmaceutical compositions, and kits are provided for treating a subject with an effective amount of an oxytocin receptor (OXTR) agonist and an effective amount of an ALK5 antagonist. In certain aspects, the OXTR agonist may be oxytocin or an oxytocin analog (e.g., a small molecule). The ALK 5 antagonist may be a small molecule, such as 2-(3-(6-Methyl-pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine, LY2157299, A 83-01, D 4476, GW 788388, LY 364947, Rep Sox, SB 431542, SB 505124, SB 525334, or SD 208. In certain aspects, the amounts of the OXTR agonist and ALK5 antagonist may be sufficient to induce muscle regeneration and/or neural cell regeneration in the subject.
    Type: Application
    Filed: August 12, 2015
    Publication date: August 24, 2017
    Inventors: Irina M. Conboy, David Vernon Schaffer, Hanadie Yousef, Michael J. Conboy, Wendy Cousin, Christian Elabd
  • Publication number: 20170145105
    Abstract: Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include reducing cell surface VCAM-1 activity in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 25, 2017
    Inventors: Anton Wyss-Coray, Hanadie Yousef
  • Publication number: 20140356947
    Abstract: Methods and compositions for somatic cell proliferation as well as increasing viability of somatic cells are provided. The compositions include heparin binding protein isolated from a medium conditioned by growth of pluripotent stem cells, such as, human embryonic stem cells, human embryonic carcinoma cells. The methods include contacting a somatic cell with a heparin binding protein composition for a sufficient period of time to provide for enhanced proliferation and/or viability of the somatic cell as compared to the absence of the heparin binding protein composition.
    Type: Application
    Filed: May 27, 2014
    Publication date: December 4, 2014
    Inventors: Irina M. Conboy, Michael J. Conboy, Hanadie Yousef, David V. Schaffer
  • Publication number: 20120045395
    Abstract: The present invention relates to the discovery that certain microRNAs are differentially expressed in Idiopathic Pulmonary Fibrosis. The present invention provides for diagnostic methods, therapeutic methods, and kits related to these differentially expressed microRNAs.
    Type: Application
    Filed: March 21, 2011
    Publication date: February 23, 2012
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: Naftali Kaminski, Panagiotis Benos, David Corcoran, Kusum V. Pandit, Jadranka Milosevic, Hanadie Yousef