Patents by Inventor Hanbiao Wang
Hanbiao Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11806156Abstract: Computer implemented methods and systems for monitoring cardiac activity (CA) signals, for a series of beats, over first and second sensing channels having different first and second detection thresholds, respectively. The methods and systems also include analyzing the CA signals over the first and second sensing channels utilizing the first and second detection thresholds, respectively, during an event prediction window to detect a presence of sensed events. The methods and systems also include determining amplitudes of the sensed events detected. The methods and systems also include calculating at least one of an amplitude distribution or amplitude trend for the sensed events detected over the first and second channels and adjusting at least one of the first or second detection thresholds based on the at least one of the amplitude distribution or amplitude trend.Type: GrantFiled: March 4, 2021Date of Patent: November 7, 2023Assignee: Pacesetter, Inc.Inventors: Hanbiao Wang, Xing Pei, Kyungmoo Ryu
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Publication number: 20210330239Abstract: Computer implemented methods and systems for monitoring cardiac activity (CA) signals, for a series of beats, over first and second sensing channels having different first and second detection thresholds, respectively. The methods and systems also include analyzing the CA signals over the first and second sensing channels utilizing the first and second detection thresholds, respectively, during an event prediction window to detect a presence of sensed events. The methods and systems also include determining amplitudes of the sensed events detected. The methods and systems also include calculating at least one of an amplitude distribution or amplitude trend for the sensed events detected over the first and second channels and adjusting at least one of the first or second detection thresholds based on the at least one of the amplitude distribution or amplitude trend.Type: ApplicationFiled: March 4, 2021Publication date: October 28, 2021Inventors: Hanbiao Wang, Xing Pei, Kyungmoo Ryu
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Publication number: 20210327574Abstract: Methods, devices and program products are provided and include memory to store a baseline task handling (TH) pattern and TH circuitry including one or more processors. The TH circuitry is configured to perform tasks associated with one or more of collecting one or more CA signals or environmental event signals. The TH circuitry analyzes the one or more CA signals or environmental event signals, delivers therapy, detects communications requests, or maintains communications sessions with an external device. The IMD monitors a TH characteristic in connection with the performing the tasks, compares the TH characteristic to the baseline TH pattern and implements a corrective action in response to the compare of the TH characteristic and the baseline TH pattern.Type: ApplicationFiled: April 21, 2020Publication date: October 21, 2021Inventors: Hanbiao Wang, Xing Pei
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Patent number: 10820820Abstract: Described herein are implantable systems and devices, and methods for use therewith, that distinguish between different signal components of interest in sensed physiologic signals with high sensitivity and specificity. Such a method can include obtaining a sensed signal using an IMD and using a plurality of different filters that are parallel to one another to simultaneously filter the sensed signal, and/or copies thereof, to produce different filtered signals. Where each filter has a respective passband that does not substantially overlap with the passband(s) of the other filter(s), each of the different filtered signals will be indicative of different frequency content of the sensed signal. Additionally, amplitudes of temporally aligned peaks in at least two of the different filtered signals can be detected, and one or more peaks of the sensed signal can be classified based on the detected amplitudes of the temporally aligned peaks in the different filtered signals.Type: GrantFiled: March 16, 2018Date of Patent: November 3, 2020Assignee: Pacesetter, Inc.Inventors: Hanbiao Wang, Xing Pei
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Publication number: 20190282113Abstract: Described herein are implantable systems and devices, and methods for use therewith, that distinguish between different signal components of interest in sensed physiologic signals with high sensitivity and specificity. Such a method can include obtaining a sensed signal using an IMD and using a plurality of different filters that are parallel to one another to simultaneously filter the sensed signal, and/or copies thereof, to produce different filtered signals. Where each filter has a respective passband that does not substantially overlap with the passband(s) of the other filter(s), each of the different filtered signals will be indicative of different frequency content of the sensed signal. Additionally, amplitudes of temporally aligned peaks in at least two of the different filtered signals can be detected, and one or more peaks of the sensed signal can be classified based on the detected amplitudes of the temporally aligned peaks in the different filtered signals.Type: ApplicationFiled: March 16, 2018Publication date: September 19, 2019Inventors: Hanbiao Wang, Xing Pei
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Patent number: 8798733Abstract: An implantable medical device includes leads having electrodes that are positioned within a heart. The electrodes sense signals derived from the heart that include waveform segments. The device includes a timing module that determines when the waveform segments cross a threshold and measures time intervals between at least two threshold crossings by the waveform segments. The device also includes event identification module that compares the time intervals to a predetermined pattern associated with a cardiac event. The event identification module identifies the cardiac event based on the time intervals and the predetermined pattern.Type: GrantFiled: April 6, 2010Date of Patent: August 5, 2014Assignee: Pacesetter, Inc.Inventors: Hanbiao Wang, Bonian Dai, Iman Ahmadi, Erik Brockman
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Publication number: 20140169162Abstract: A medical telemetry system and method are provided for communication between an implantable medical device (IMD) and an external device (ExD). The method and system collects real-time (RT) data and non-real-time (NRT) data. The method and system segment the RT data into RT packets and the NRT data into NRT packets and load the RT and NRT packets into a shared transmit buffer in the IMD in accordance with RT and NRT bandwidth allocations and/or packet size. The method and system transmit the RT and NRT packets from the IMD to the ExD in an order loaded in the transmit buffer and adjust at least one of the RT and NRT bandwidth allocations and/or packet size based on a quality of service (QoS) characteristic.Type: ApplicationFiled: December 17, 2012Publication date: June 19, 2014Applicant: ST. JUDE MEDICAL ABInventors: Roberto Romano, Nicklas Blidmo, Anders Becker, Par Edlund, Leif Lychou, Hanbiao Wang, Ing-Sheng Peter Yin, Thanh Tieu
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Patent number: 8165675Abstract: Techniques are described for discriminating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) using an implantable medical device capable of multi-site ventricular sensing. In one example, ventricular depolarization events are detected within a patient by the implantable device during a tachyarrhythmia, at both a left ventricular sensing site and a right ventricular sensing site. Ventricular event timing differences are then ascertained. The device compares the ventricular event timing differences detected during the tachyarrhythmia with predetermined supraventricular event timing differences for the patient, such as event timing differences previously detected within the patient during sinus rhythm or extrapolated from sinus rhythm values. The device then distinguishes VT from SVT based on the comparison of the event timing differences detected during the tachyarrhythmia with the predetermined supraventricular event timing differences.Type: GrantFiled: October 29, 2009Date of Patent: April 24, 2012Assignee: Pacesetter, Inc.Inventors: Hanbiao Wang, Bonian Dai, Xing Pei
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Publication number: 20110245698Abstract: An implantable medical device includes leads having electrodes that are positioned within a heart. The electrodes sense signals derived from the heart that include waveform segments. The device includes a timing module that determines when the waveform segments cross a threshold and measures time intervals between at least two threshold crossings by the waveform segments. The device also includes event identification module that compares the time intervals to a predetermined pattern associated with a cardiac event. The event identification module identifies the cardiac event based on the time intervals and the predetermined pattern.Type: ApplicationFiled: April 6, 2010Publication date: October 6, 2011Applicant: PACESETTER, INC.Inventors: Hanbiao Wang, Bonian Dai, Iman Ahmadi, Erik Brockman
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Patent number: 7991472Abstract: A method for diagnosing an implantable cardiac device including a plurality of implanted leads may include: monitoring a plurality of parameters associated with the plurality of implanted leads; detecting a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnosing a problem with the implantable cardiac device based on the detected change and the evaluation. A system for diagnosing an implantable cardiac device including a plurality of implanted leads may include an implantable pacing device and a processor. The processor may be configured to: monitor a plurality of parameters associated with the plurality of implanted leads; detect a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnose a problem with the implantable cardiac device based on the detected change and the evaluation.Type: GrantFiled: October 8, 2008Date of Patent: August 2, 2011Assignee: Pacesetter, Inc.Inventors: Paul A. Levine, Hanbiao Wang, Bonian Dai, Robert E. Smith, Jr.
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Publication number: 20110106194Abstract: Techniques are described for discriminating ventricular tachycardia (VT) from supraventricular tachycardia (SVT) using an implantable medical device capable of multi-site ventricular sensing. In one example, ventricular depolarization events are detected within a patient by the implantable device during a tachyarrhythmia, at both a left ventricular sensing site and a right ventricular sensing site. Ventricular event timing differences are then ascertained. The device compares the ventricular event timing differences detected during the tachyarrhythmia with predetermined supraventricular event timing differences for the patient, such as event timing differences previously detected within the patient during sinus rhythm or extrapolated from sinus rhythm values. The device then distinguishes VT from SVT based on the comparison of the event timing differences detected during the tachyarrhythmia with the predetermined supraventricular event timing differences.Type: ApplicationFiled: October 29, 2009Publication date: May 5, 2011Applicant: PACESETTER, INC.Inventors: Hanbiao Wang, Bonian Dai, Xing Pei
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Publication number: 20100087891Abstract: A method for diagnosing an implantable cardiac device including a plurality of implanted leads may include: monitoring a plurality of parameters associated with the plurality of implanted leads; detecting a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnosing a problem with the implantable cardiac device based on the detected change and the evaluation. A system for diagnosing an implantable cardiac device including a plurality of implanted leads may include an implantable pacing device and a processor. The processor may be configured to: monitor a plurality of parameters associated with the plurality of implanted leads; detect a change in one of the parameters; evaluating at least one of the other parameters upon detection of the change; and diagnose a problem with the implantable cardiac device based on the detected change and the evaluation.Type: ApplicationFiled: October 8, 2008Publication date: April 8, 2010Applicant: PACESETTER, INC.Inventors: Paul A. Levine, Hanbiao Wang, Bonian Dai, Robert E. Smith, JR.
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Patent number: RE49948Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.Type: GrantFiled: February 3, 2022Date of Patent: April 30, 2024Assignee: Peloton Therapeutics, Inc.Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang