Patents by Inventor Handong Xu

Handong Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for onset time detection of acoustic emission based on histogram distance
    Patent number: 11971950
    Abstract: The present invention discloses a method for onset time detection of a time-domain acoustic emission signal based on histogram distance. The method comprises the following steps: acquiring an acoustic emission signal; dividing the signal into two intervals with a sliding point k as the demarcation point; obtaining the relative frequency histograms of two adjacent intervals; obtaining histogram distance of the relative frequency histograms of two adjacent intervals; moving the sliding point k to the next element to obtain two new intervals and generating new histograms of the two new intervals and calculating the histogram distance of two new intervals; searching for the point which gives the maximum value of the histogram distances, and the corresponding time to this point is regarded as the onset time.
    Type: Grant
    Filed: March 25, 2022
    Date of Patent: April 30, 2024
    Inventors: Zhensheng Yang, Handong Xu, Haoda Li, Bangping Gu, Junliang He
  • NUCLEIC ACID SEQUENCING USING AFFINITY REAGENTS
    Publication number: 20240117425
    Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
    Type: Application
    Filed: September 7, 2023
    Publication date: April 11, 2024
    Inventors: Radoje Drmanac, Snezana Drmanac, Handong Li, Xun Xu, Matthew J. Callow, Leon Eckhardt, Naibo Yang
  • MODIFIED NUCLEOSIDE OR NUCLEOTIDE
    Publication number: 20240067673
    Abstract: A modified nucleoside or nucleotide, the 3?-OH of the modified nucleoside or nucleotide being reversibly blocked; meanwhile, the present invention also relates to a kit comprising the nucleoside or nucleotide, and a sequencing method based on the nucleoside or nucleotide.
    Type: Application
    Filed: October 21, 2021
    Publication date: February 29, 2024
    Inventors: Xun XU, Bo TENG, Wenwei ZHANG, Ao CHEN, Handong LI, Shengyi YAN, Shitian ZHUO, Liang SHEN, Yonghui ZHANG, Nanfeng GAO, Jie ZHAO, Sha LIAO
  • Method for Onset Time Detection of Acoustic Emission Based on Histogram Distance
    Publication number: 20230130080
    Abstract: The present invention discloses a method for onset time detection of acoustic emission signals based on histogram distance. The method comprises the following steps: acquiring an acoustic emission signal; dividing the signal into two intervals with a sliding point k as the demarcation point; obtaining the relative frequency histograms of two adjacent intervals; obtaining histogram distance of the relative frequency histograms of two adjacent intervals; moving the sliding point k to the next element to obtain two new intervals and generating new histograms of the two new intervals and calculating the histogram distance of two new intervals; searching for the point which gives the maximum value of the histogram distances, and the corresponding time to this point is regarded as the onset time.
    Type: Application
    Filed: March 25, 2022
    Publication date: April 27, 2023
    Inventors: Zhensheng Yang, Handong Xu, Haoda Li, Bangping Gu, Junliang He