Abstract: An efficient blasting method for similar cutting in a rock tunnel is provided, which relates to the technical field of rock tunneling. The method includes the following steps: drilling: drilling central holes, lower cutting holes, upper cutting holes, auxiliary holes and peripheral holes in a cross section area for tunnel construction; filling explosives: filling explosives into the central holes, the lower cutting holes, the upper cutting holes, the auxiliary holes and the peripheral holes; and blasting: blasting following blast holes in turn to complete full-face one-time blasting in a millisecond delay blasting mode. The method is applicable for construction scenes of drilling and blasting methods.

Abstract: A method for preparing a combination adjuvant is based on carboxyl modified aluminum oxyhydroxide nanoparticles. The preparation method uses carboxylated hydroxyl oxide nanoparticles as a carrier, but is not limited to the role of a carrier. The carboxylated hydroxyl oxide nanoparticles are combined with a novel CpG-ODN adjuvant, such that the half-life period of a CpG adjuvant is prolonged. The combination of adjuvants shows a synergistic effect, such that the Th2 type immune stimulation ability is enhanced, and the possibility of Th1 type immunity is also given to the adjuvant.