Patents by Inventor Hang Hubert YIN

Hang Hubert YIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Toll-Like Receptor 8 (TLR8)-Specific Antagonists and Methods of Making and Uses Thereof
    Publication number: 20230132035
    Abstract: Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.
    Type: Application
    Filed: October 10, 2022
    Publication date: April 27, 2023
    Inventors: Hang Hubert Yin, Shuting Zhang, Zhenyi Hu
  • SMALL-MOLECULE REGULATOR OF TLR8
    Publication number: 20230002327
    Abstract: Provided in the present disclosure is a small-molecule regulator of TLR8; a compound of formula (I) or the pharmaceutically acceptable salt thereof provided in the present disclosure has good TLR8 regulatory activity and can be used to prevent or treat diseases mediated by TLR8.
    Type: Application
    Filed: June 22, 2020
    Publication date: January 5, 2023
    Applicant: TSINGHUA UNIVERSITY
    Inventors: Hang Hubert YIN, Shuangshuang JIANG
  • Toll-like receptor 8 (TLR8) specific antagonists and methods of making and uses thereof
    Patent number: 11466010
    Abstract: Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: October 11, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Hang Hubert Yin, Shuting Zhang, Zhenyi Hu
  • Toll-Like Receptor 8 (TLR8) Specific Antagonists and Methods of Making and Uses Thereof
    Publication number: 20210179621
    Abstract: Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.
    Type: Application
    Filed: October 30, 2018
    Publication date: June 17, 2021
    Inventors: Hang Hubert Yin, Shuting Zhang, Zhenyi Hu
  • Anthracycline prodrugs and methods of making and using the same
    Patent number: 10912767
    Abstract: The present invention includes compounds of the class anthracycline that have been modified to include photo-activated prodrug anthracycline compounds that are useful in the treatment of cancer. One example composition of the invention may include photodoxazolidine which may be synthesized in two steps from 4,5-dimethoxy-2-nitrobenzyl alcohol and doxazolidine. In this embodiment commercial 4,5-dimethoxyl-2-nitrobenzyl alcohol reacts with p-nitrophenylchloroformate to give the p-nitrophenyl carbonate of the benzyl alcohol derivative. The p-nitrophenyl carbonate is then reacted with doxazolidine to give the exemplary photodoxazolidine composition.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: February 9, 2021
    Assignee: THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Tad H. Koch, Benjamin L. Barthel, Hang Hubert Yin, Ryo Tamura, Alla Balabanova
  • ANTHRACYCLINE PRODRUGS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20180110756
    Abstract: Therapeutically effective prodrug compounds for the prevention and treatment of cancer and pharmaceutical compositions containing these compounds as well as methods of making and using these compounds.
    Type: Application
    Filed: April 27, 2016
    Publication date: April 26, 2018
    Inventors: Tad H. KOCH, Benjamin L. BARTHEL, Hang Hubert YIN, Ryo TAMURA, Alla BALABANOVA