Patents by Inventor Hang-Sub Kim

Hang-Sub Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer
    Patent number: 6894073
    Abstract: The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene compound that include kamebanin, kamebacetal A, kamebakaurin, and exisanin A, which would be effective for the treatment inflammation, immune disease or cancer by inhibiting the production of nitric oxide, prostaglandin, and TNF-a1 through the suppression of NF-k B activity.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: May 17, 2005
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung-Joon Lee, Jeong-Hyung Lee, Hang-Sub Kim, Young-Soo Hong, Bang-Yeon Hwang
  • Novel use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer
    Publication number: 20040048918
    Abstract: The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene compound that include kamebanin, kamebacetal A, kamebakaurin, and exisanin A, which would be effective for the treatnent inflammation, immune disease or cancer by inhibiting the production of nitric oxide, prostaglandin, and TNF-a, through the suppression of NF-k B activity.
    Type: Application
    Filed: June 11, 2003
    Publication date: March 11, 2004
    Inventors: Jung-Joon Lee, Jeong-Hyung Lee, Hang-Sub Kim, Young-Soo Hong, Bang-Yeon Hwang
  • Isocoumarin derivatives inhibiting angiogenesis
    Patent number: 6451846
    Abstract: The present invention relates to novel isocoumarin derivatves inhibiting angiogenesis, a method for preparation thereof and pharmaceutical compositions comprising the said derivatives as pharmaceutically active ingredients. More particularly, the present invention relates to novel isocoumarin derivatves represented by formula (1), especially 6,8-dihydroxy-4-acetyl-isocoumarin, a method for preparing 6,8-dihydroxy-4-acetyl-isocoumarin from fungi, and pharmaceutical compositions comprising the compounds and/or 6,8-dihydroxy-4-acetyl-isocoumarin as pharmaceutically active ingredients, which would be effective for the treatment of angiogenic diseases such as cancers, rheumatoid arthritis and diabetic retinopathy.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: September 17, 2002
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jung Joon Lee, Hang-Sub Kim, Jeong-Hyung Lee, Young-Soo Hong, Yun Joo Park
  • Aklavinone C-11 hydroxylase, gene coding for same, expression vector therefor, and process for preparing hybrid antibiotics by using said vector
    Patent number: 5843735
    Abstract: Aklavinone C-11 hydroxylase separated from Streptomyces sp.; a gene encoding same; an expression vector comprising said gene; a microorganism transformed with said vector; and a process for preparing novel hybrid anthracyclines by using said vector.
    Type: Grant
    Filed: October 31, 1995
    Date of Patent: December 1, 1998
    Assignees: Korea Institute of Science and Technology, IL Dong Pharmaceutical Co., Ltd.
    Inventors: Jung-Joon Lee, Young-Ho Kim, Soon-Kwang Hong, Young-Soo Hong, Cheol-Kyu Hwang, Hang-Sub Kim