Abstract: In one aspect, antibodies that bind to subdomain II of human HER2 are provided. In another aspect, antibodies comprising a light chain polypeptide that pairs with both a heavy chain polypeptide for binding to subdomain II of human HER2 and a heavy chain polypeptide for binding to subdomain IV of human HER2 are provided. In a further aspect, antibodies that bind to both subdomain II and subdomain IV of human HER2 comprising a common light chain polypeptide are provided. Methods of treating a cancer or treating brain metastasis of a cancer using these antibodies are also provided.

Abstract: In one aspect, bispecific proteins having the ability to specifically bind to both subdomain II of human HER2 and subdomain IV of human HER2 are provided. In another aspect, methods of treating a cancer or treating brain metastasis of a cancer using a bispecific protein that specifically binds to subdomain II and subdomain IV of human HER2 are provided.

Abstract: Provided herein are conjugates comprising proteins that bind to a transferrin receptor and oligonucleotides that are capable of modulating the expression of a target gene or sequence, as well as methods of use thereof.

Abstract: The invention relates to a composite material based on boron nitride (BN(C)) in the form of a continuous structure; and a phase change material (PCM) incorporated within said continuous BN(C) structure and is embedded within a polymer layer, a process for manufacturing same, and the components that comprise same.

Abstract: In one aspect, bispecific proteins having the ability to specifically bind to both subdomain II of human HER2 and subdomain IV of human HER2 are provided. In another aspect, methods of treating a cancer or treating brain metastasis of a cancer using a bispecific protein that specifically binds to subdomain II and subdomain IV of human HER2 are provided.

Abstract: The present disclosure provides method and apparatus for providing a response to a user in a question-answering session. A message may be received in the session, the session being between the user and an electronic conversational agent. Context information is extracted from a context database based at least on the message. Fact information and emotion information are obtained from at least one of the message and the context information. The fact information is associated with at least one fact, and the emotion information is associated with emotions towards the at least one fact. A response is generated based at least on the fact information and the emotion information. The response is provided to the user.

Abstract: A chemical vapor deposition process comprising heating a porous metal template at a temperature range of 500 to 2000° C.; and passing a gas mixture comprising a carrier gas carrying along a vapor of an organometallic compound and at least one of a carbon precursor gas and a boron nitride precursor gas through the heated metal template is provided. The heating temperature causes the decomposition of the organometallic compound vapor into metal particles, the carbon precursor gas into graphene domains, and/or the boron nitride precursor gas into hexagonal-boron nitride domains. The graphene domains and/or the hexagonal-boron nitride domains nucleate and grow on the metal particles and the metal template to form a three-dimensional interconnected porous network of graphene and/or the hexagonal-boron nitride. A foam-like structure produced by a process as described above is also provided.

Abstract: The invention relates to a composite material based on boron nitride (BN(C)) in the form of a continuous structure; and a phase change material (PCM) incorporated within said continuous BN(C) structure and is embedded within a polymer layer, a process for manufacturing same, and the components that comprise same.

Abstract: The present disclosure provides method and apparatus for providing a response to a user in a question-answering session. A message may be received in the session, the session being between the user and an electronic conversational agent. Context information is extracted from a context database based at least on the message. Fact information and emotion information are obtained from at least one of the message and the context information. The fact information is associated with at least one fact, and the emotion information is associated with emotions towards the at least one fact. A response is generated based at least on the fact information and the emotion information. The response is provided to the user.

Abstract: The present invention relates to a boron nitride (BN(C)) composite material in the form of a continuous structure, and a phase change material (PCM) included inside said continuous structure of (BN(C)), the method for manufacturing same and the components that comprise same.

Abstract: A method of preparing a boron nitride material, such as boron nitride (BN) or boron carbonitride (BCN), is provided. The method may include providing a substrate, and sublimating an amine borane complex onto the substrate to obtain the boron nitride material. The amine borane complex may include, but is not limited to, borazine, amino borane, trimethylamine borane and triethylamine borane. In addition, the temperature at which the sublimating is carried out may be varied to control composition of the boron nitride material formed. In addition, various morphologies can be obtained by using the present method, namely films, nanotubes and porous foam.

Abstract: According to embodiments of the present invention, a composite material is provided, comprising an interconnected network comprising a material that is thermally conductive and electrically insulative, and a polymer. Preferably, the composite material comprises hexagonal boron nitride network and polyimide. The hexagonal boron nitride network is preferably formed on a template by chemical vapour deposition. The interconnected network is preferably about 0.3 vol % or less of the composite material. According to further embodiments of the present invention, a method of forming a composite material, and an electrical component are also provided. Said composite material may be useful as flexible electrical elements.

Abstract: A chemical vapor deposition process comprising heating a porous metal template at a temperature range of 500 to 2000° C.; and passing a gas mixture comprising a carrier gas carrying along a vapor of an organometallic compound and at least one of a carbon precursor gas and a boron nitride precursor gas through the heated metal template is provided. The heating temperature causes the decomposition of the organometallic compound vapor into metal particles, the carbon precursor gas into graphene domains, and/or the boron nitride precursor gas into hexagonal-boron nitride domains. The graphene domains and/or the hexagonal-boron nitride domains nucleate and grow on the metal particles and the metal template to form a three-dimensional interconnected porous network of graphene and/or the hexagonal-boron nitride. A foam-like structure produced by a process as described above is also provided.

Abstract: A method of preparing a boron nitride material, such as boron nitride (BN) or boron carbonitride (BCN), is provided. The method may include providing a substrate, and sublimating an amine borane complex onto the substrate to obtain the boron nitride material. The amine borane complex may include, but is not limited to, borazine, amino borane, trimethylamine borane and triethylamine borane. In addition, the temperature at which the sublimating is carried out may be varied to control composition of the boron nitride material formed. In addition, various morphologies can be obtained by using the present method, namely films, nanotubes and porous foam.

Abstract: A polyimide produced from a polyamic acid solution of PMDA-ODA (pyromellitic dianhydryde-oxydianiline) in N-methyl-2-pyrrolidone (NMP).

Abstract: A filtered cathodic vacuum arc apparatus and method for the generation of a nanocluster film or compound film with improved characteristics onto a substrate and thin film materials, carbon-encapsulated metal nanoclusters and carbon nanotubes formed through the use of said apparatus and method. The apparatus includes a deposition chamber, a substrate holder for holding a substrate within the deposition chamber, means for simultaneously generating a first beam of plasma and a second beam of plasma from a first and a second plasma source, respectively, a Y-bend magnetic filter to direct the plasma towards a substrate on the substrate holder and an anti-Helmholtz coil set-up within the deposition chamber, wherein the Y-bend magnetic filter and anti-Helmholtz coil set up cause first and second beams of plasma to mix.

Abstract: A robotic pet-sitter system comprises a control system and a robotic body, the control system used to wireless launch control instruction signals; a wireless receiver module is defined in the robotic body, used to receive control instruction signals and to process the control instruction signals into control signals, the robotic body further comprises a driving system and a feeding module, the driving system used to drive the robotic body moving according to the control signals, the feeding module used to open the feeding box placed with pet food according to the control signals. The local PC communicates with a remote PC through Internet, and the remote PC long-distance controls the robotic body and monitors pet through Internet. The robotic pet-sitter system of the present invention can care for and monitor the pet when the owner is not at home.

Abstract: A robotic pet-sitter system comprises a control system and a robotic body, the control system used to wireless launch control instruction signals; a wireless receiver module is defined in the robotic body, used to receive control instruction signals and to process the control instruction signals into control signals, the robotic body further comprises a driving system and a feeding module, the driving system used to drive the robotic body moving according to the control signals, the feeding module used to open the feeding box placed with pet food according to the control signals. The local PC communicates with a remote PC through Internet, and the remote PC long-distance controls the robotic body and monitors pet through Internet. The robotic pet-sitter system of the present invention can care for and monitor the pet when the owner is not at home.

Abstract: The present invention generally relates to apparatuses having some characteristic(s) of traditional “roly-poly” toys, which are traditional passive toys that, when struck, wobble about their typically-rounded base but stay upright due to bottom-heavy weighting. Some embodiments of the present invention can be especially relevant to such an apparatus that is mobile and/or not totally passive.

Abstract: The present invention generally relates to apparatuses having some characteristic(s) of traditional “roly-poly” toys, which are traditional passive toys that, when struck, wobble about their typically-rounded base but stay upright due to bottom-heavy weighting. Some embodiments of the present invention can be especially relevant to such an apparatus that is mobile and/or not totally passive.