Abstract: The application discloses an engineered phosphatidylserine decarboxylase (PSD protein) and use thereof, a fusion protein comprising the engineered PSD protein and use thereof, a nucleic acid molecule for encoding the engineered PSD protein or the fusion protein, an expression vector comprising the nucleic acid molecule, an engineered cell comprising the nucleic acid molecule or the expression vector, a method for preparing an engineered extracellular vesicle, an engineered extracellular vesicle and use thereof. In this application, an engineered phosphatidylserine decarboxylase is used for catalyzing phosphatidylserine on the surface of an extracellular vesicle, so that phagocytosis of macrophages is reduced, in-vivo clearance is reduced, and the circulation time of the extracellular vesicle is prolonged.

Abstract: The present disclosure provides a system and method that determines, by a charging station, that a vehicle is aligned to a predetermined charging position. The predetermined charging position is a location at which a first set of electrical contacts on the charging station aligns with a second set of electrical contacts on the vehicle. The system and method deploys, by the charging station, a charging station interlock system that prevents the vehicle from moving in response to determining that the vehicle is aligned to the predetermined charging position. The system and method charges the vehicle using the first set of electrical contacts coupled to the second set of electrical contacts in response to the deploying of the charging station interlock system.

Abstract: A bifunctional nucleoside hydrogel is formed by dissolving isoguanosine, guanosine and a borate in water or an aqueous solution and then crosslinking same. The bifunctional nucleoside hydrogel integrates a carrier and a drug effect and has a significant inhibitory effect on the activity of tumor cells, and in particular has a significant inhibitory effect on the activity of cells related to lung cancer, glioma, osteoma, colon cancer, breast cancer, oral squamous cell carcinoma and tongue squamous cell carcinoma, of which the inhibitory effect on the activity of cells related to oral squamous cell carcinoma is the best. Therefore, the bifunctional nucleoside hydrogel has potential application prospects in preparing anti-tumor drugs, and particularly, same can provide a new approach for treating oral squamous cell carcinoma.

Abstract: The invention provides a carbon dioxide-based polyurethane elastomer with damping and anti-fatigue aging properties and its preparation method. It is obtained from Component A and Component B; Component A includes: PTMG-1000 45˜60 parts, carbon dioxide-based polyol 25˜30 parts, poly-DOPO-ITA-pentanediol ester 10˜20 parts, BDO 3˜5 parts, water 0.3˜0.5 parts, N-methylimidazole 0.5˜0.8 parts, bis(2-dimethylaminoethyl) ether 0.1˜0.2 parts, needle-shaped nano-titanium dioxide 0.5 parts, hindered phenol 0.2˜0.5 parts, dibutyltin dilaurate 0.1˜0.3 parts, strontium chloride 0.005˜0.01 parts, rhodium chloride 0.02˜0.03 parts, foaming agent 0.2˜0.5 parts; Component B includes: carbon dioxide-based polyol 50˜55 parts, MDI-50 45˜50 parts, organic zinc 0.01˜0.02 parts, organic bismuth 0.01˜0.02 parts.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for agent trajectory prediction using vectorized inputs.

Abstract: Disclosed are a virtual object display method and apparatus, an electronic device, and a readable medium. The method comprises: recognizing a trigger gesture from hand images according to three-dimensional coordinates of a hand key point, the hand images comprising at least two continuous frames of first hand images in which the hand key point is relatively stationary, at least one frame of a second hand image in which the hand key point moving relative to the first hand image, and a gesture of at least one of the first hand images and the second hand image being the trigger gesture; in response to the trigger gesture, determining a throwing parameter according to the hand images; simulating a trajectory of a thrown virtual object according to the throwing parameter and displaying the trajectory in an augmented reality scene.

Abstract: A supramolecular hydrogel capable of delivering lipophilic medicaments, a preparation method therefor, and uses thereof are provided. The structure of the supramolecular hydrogel is represented by Formula I, in which R1 and R2 are each independently selected from palmitoyl or oleoyl, respectively. The hydrogel can be used as a drug delivery system, and encapsulate and load various medicaments. In particular, it has good controlled-release for hydrophobic medicaments.

Abstract: This disclosure provides methods and apparatuses for providing interpretability for multivariate time-series data anomaly detection. The multivariate time-series data anomaly detection is performed, through a multivariate time-series data anomaly detection model, for a multivariate time-series data formed by multiple time-series data. An anomaly detection result indicating at least an anomaly period is obtained from the model. An anomaly period correlation metric of the multiple time-series data in the anomaly period is determined. A trace-back period correlation metric of the multiple time-series data in a trace-back period before the anomaly period is determined. At least one time-series data pair having abnormal correlation in the anomaly period is identified from the multiple time-series data, based on a difference between the anomaly period correlation metric and the trace-back period correlation metric.

Abstract: Provided in the present application are an anti-periostin humanized monoclonal antibody, and a preparation method therefor and the use thereof. The anti-periostin humanized monoclonal antibody has a relatively high expression level, and also has a better binding specificity and affinity to an antigen.

Abstract: A micro-fluxgate sensor has a double-iron core assembly, a self-oscillating module, a current superimposing and amplifying module and a voltage acquisition module. The double-iron core assembly comprises a first iron core and a second iron core. The first iron core is provided with a first winding coil. The second iron core is provided with a second winding coil. The first winding coil and the second winding coil are respectively connected with an input end of the self-oscillating module, and an output end of the self-oscillating module is respectively connected with the current superimposing and amplifying module and the voltage acquisition module. The fluxgate sensor is simple in processing circuit without manual debugging and is easily integrated.

Abstract: An air fryer includes a machine body, a smoke box provided at the machine body, and a heating member provided at the machine body. The machine body includes a cooking cavity and an oil receiving tray located at one side of the cooking cavity and including a flow-passing member. The smoke boxy communicates with the cooking cavity through the flow-passing member. The heating member is configured to at least supply heat to the smoke box.

Abstract: An image processing method, apparatus, electronic device and storage medium are provided. The method includes: acquiring a depth image corresponding to a target image; determining a first undirected graph according to the target image and the depth image, the first undirected graph including a first node corresponding to a background edge and a second node corresponding to a foreground edge, and there being no edge connection between the first node and the second node; and deriving one or more third nodes by taking the first node as a reference to obtain a second undirected graph.

Abstract: Methods, computer systems, and apparatus, including computer programs encoded on computer storage media, for predicting future trajectories for an agent in an environment. A system obtains scene context data characterizing the environment. The scene context data includes data that characterizes a trajectory of an agent in a vicinity of a vehicle in an environment up to a current time point. The system identifies a plurality of initial target locations in the environment. The system further generates, for each of a plurality of target locations that each corresponds to one of the initial target locations, a respective predicted likelihood score that represents a likelihood that the target location will be an intended final location for a future trajectory of the agent starting from the current time point.

Abstract: Example embodiments relate to techniques for three dimensional (3D) object detection and localization. A computing system may cause a radar unit to transmit radar signals and receive radar reflections relative to an environment of a vehicle. Based on the radar reflections, the computing system may determine a heading and a range for a nearby object. The computing system may also receive an image depicting a portion of the environment that includes the object from a vehicle camera and remove peripheral areas of the image to generate an image patch that focuses upon the object based on the heading and the range for the object. The image patch and the heading and the range for the object can be provided as inputs into a neural network that provides output parameters corresponding to the object, which can be used to control the vehicle.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for agent trajectory prediction using temporal-spatial interaction predictions.

Abstract: The present disclosure relates to the technical field of plasma cleaning, and provides a plasma cleaning head for an optical member and a plasma cleaning device, including a plasma circulation assembly having a hollow shape and a lens frame mounted on the plasma circulation assembly, wherein the plasma circulation assembly is provided with an outlet port which is larger than an ejection port adapted to eject a plasma and is adapted to diffuse the plasma, and the lens frame is in communication with and surrounds the outlet port, and the lens frame is adapted to embed an optical lens body so that the optical lens body is arranged opposite to the outlet port to help improve dispersion and stability of the plasma flowing from the outlet port to the optical lens body, and helps to promote the energy absorption of the plasma by the optical lens body.

Abstract: A system obtains scene context data characterizing the environment. The scene context data includes data that characterizes a trajectory of an agent in a vicinity of a vehicle up to a current time point. The system identifies a plurality of initial target locations, and generates, for each of a plurality of target locations that each corresponds to one of the initial target locations, a respective predicted likelihood score that represents a likelihood that the target location will be an intended final location for a future trajectory of the agent. For each target location in a first subset of the target locations, the system generates a predicted future trajectory for the agent given that the target location is the intended final location for the future trajectory. The system further selects, as likely future trajectories of the agent, one or more of the predicted future trajectories.

Abstract: Methods, computer systems, and apparatus, including computer programs encoded on computer storage media, for predicting future trajectories for an agent in an environment. A system obtains scene context data characterizing the environment. The scene context data includes data that characterizes a trajectory of an agent in a vicinity of a vehicle in an. environment up to a current time point. The system identifies a plurality of initial target locations in the environment. The system further generates, for each of a plurality of target locations that each corresponds to one of the initial target locations, a respective predicted likelihood score that represents a likelihood that the target location will be an intended final location for a future trajectory of the agent starting from the current time point.

Abstract: In one aspect, the present disclosure provides compounds such as those with one or more quaternary ammonium ions joined by one or more aromatic rings. These compounds may have a formula: These compounds may be used in the treatment of a microbial infection such as a bacterial infection including infections of drug resistant strains of bacteria.

Abstract: The present invention provides a long-acting glucagon derivative whose amino acid sequence includes a sequence as shown in SEQ ID NO. 9. The long-acting glucagon derivative of the present invention shows in animal experiments that, compared with a similar fatty acid-modified GLP-1R single agonist Semaglutide (see J Med Chem. 2015, 58 (18): 7370-80), its glucose tolerance and activity of reducing weight in mice are both stronger and can maintain for a longer time.