Patents by Inventor Hanhua Huang

Hanhua Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20220313833
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 6, 2022
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 11400163
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: August 2, 2022
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 11311627
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: April 26, 2022
    Assignee: AVIDITY BIOSCIENCES LLC
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • Motor for ceiling fan
    Patent number: 11296561
    Abstract: A ceiling fan has a motor and multiple fan blades. The motor has a stator assembly and a rotor assembly. The stator frame has a frame, a stator core, and multiple coils. The frame has multiple branch containers and multiple protrusions on the branch containers. The stator core is securely mounted in the frame. The coils are wound on the branch containers and protrusions. Therefore, the coils may be an ellipse and thus the magnetic flux therein is larger, which converts electric energy torques to drive the rotor assembly in higher efficiency. Besides, the rotor has multiple magnetic components and each magnetic component has a magnetic pole. An amount of the magnetic poles is larger than that of the branch containers. The motor can provide a higher torque even at a lower rotating speed.
    Type: Grant
    Filed: November 11, 2019
    Date of Patent: April 5, 2022
    Assignee: Foshan Carro Electrical Co., Ltd.
    Inventors: Jiansheng Zhang, Ruhui Huang, Hanhua Huang, Jianming Liang
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20220072145
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: August 31, 2021
    Publication date: March 10, 2022
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 11179472
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: November 23, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • MYC NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20210155662
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against MYC. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against MYC.
    Type: Application
    Filed: January 28, 2021
    Publication date: May 27, 2021
    Inventors: Hanhua HUANG, Rob BURKE
  • Nucleic acid-polypeptide compositions and methods of inducing exon skipping
    Patent number: 10994020
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: May 4, 2021
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • HETERODUPLEX NUCLEIC ACID MOLECULES AND USES THEREOF
    Publication number: 20210095283
    Abstract: Disclosed herein are heteroduplex nucleic acid molecules, heteroduplex nucleic acid conjugates, and pharmaceutical compositions for modulating a protein expression. Also described herein include methods of treating a disease or indication which utilize a heteroduplex nucleic acid molecule, a heteroduplex nucleic acid conjugate, or a pharmaceutical composition that comprises a heteroduplex nucleic acid molecule.
    Type: Application
    Filed: January 3, 2019
    Publication date: April 1, 2021
    Inventors: Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Rachel Elizabeth JOHNS, Rob BURKE, David Sai-Ho CHU, Michael Caramian COCHRAN, Michael David HOOD, Hanhua HUANG
  • EGFR nucleic acids and uses thereof
    Patent number: 10876121
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against EGFR. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against EGFR.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: December 29, 2020
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventor: Hanhua Huang
  • KRAS nucleic acids and uses thereof
    Patent number: 10858656
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against KRAS. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against KRAS.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: December 8, 2020
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventor: Hanhua Huang
  • Beta-catenin nucleic acids and uses thereof
    Patent number: 10844385
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against CTNNB1. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against CTNNB1.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: November 24, 2020
    Assignee: AVIDITY BIOSCIENCES, INC.
    Inventors: Hanhua Huang, Rob Burke
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20200282074
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: September 21, 2018
    Publication date: September 10, 2020
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Beatrice Diana DARIMONT, Rob BURKE, Yunyu SHI, Michael Caramian COCHRAN, Hanhua HUANG, Venkata Ramana DOPPALAPUDI, Rachel JOHNS
  • MOTOR FOR CEILING FAN
    Publication number: 20200251939
    Abstract: A ceiling fan has a motor and multiple fan blades. The motor has a stator assembly and a rotor assembly. The stator frame has a frame, a stator core, and multiple coils. The frame has multiple branch containers and multiple protrusions on the branch containers. The stator core is securely mounted in the frame. The coils are wound on the branch containers and protrusions. Therefore, the coils may be an ellipse and thus the magnetic flux therein is larger, which converts electric energy torques to drive the rotor assembly in higher efficiency. Besides, the rotor has multiple magnetic components and each magnetic component has a magnetic pole. An amount of the magnetic poles is larger than that of the branch containers. The motor can provide a higher torque even at a lower rotating speed.
    Type: Application
    Filed: November 11, 2019
    Publication date: August 6, 2020
    Inventors: JIANSHENG ZHANG, RUHUI HUANG, HANHUA HUANG, JIANMING LIANG
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20190000986
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: September 12, 2018
    Publication date: January 3, 2019
    Inventors: Arthur A. Levin, Andrew John Geall, Venkata Ramana Doppalapudi, Michael Caramian Cochran, Hanhua Huang, Rob Burke
  • NUCLEIC ACID-POLYPEPTIDE COMPOSITIONS AND METHODS OF INDUCING EXON SKIPPING
    Publication number: 20180369400
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that induce an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that induces an insertion, deletion, duplication, or alteration in an incorrectly spliced mRNA transcript to induce exon skipping or exon inclusion.
    Type: Application
    Filed: September 11, 2018
    Publication date: December 27, 2018
    Inventors: Arthur A. LEVIN, Andrew John GEALL, Venkata Ramana DOPPALAPUDI, Michael Caramian COCHRAN, Hanhua HUANG, Rob BURKE
  • EGFR NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20170362597
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against EGFR. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against EGFR.
    Type: Application
    Filed: March 31, 2017
    Publication date: December 21, 2017
    Inventor: Hanhua HUANG
  • BETA-CATENIN NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20170314030
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against CTNNB1. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against CTNNB1.
    Type: Application
    Filed: March 31, 2017
    Publication date: November 2, 2017
    Inventors: Hanhua HUANG, Rob BURKE
  • KRAS NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20170283806
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against KRAS. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against KRAS.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 5, 2017
    Inventor: Hanhua HUANG
  • PHOSPHATIDYLINOSITOL-3-KINASE NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20170283795
    Abstract: Disclosed herein are molecules and pharmaceutical compositions that mediate RNA interference against PI3K. Also described herein include methods for treating a disease or disorder that comprises a molecule or a pharmaceutical composition that mediate RNA interference against PI3K.
    Type: Application
    Filed: March 31, 2017
    Publication date: October 5, 2017
    Inventor: Hanhua HUANG