Patents by Inventor Hani HARB

Hani HARB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOTCH4 ANTIBODIES AND USES THEREOF
    Publication number: 20230365712
    Abstract: Provided herein are anti-Notch4 antibodies or antigen binding fragments thereof and their use in the treatment of a disease or disorder associated with increased levels of Notch4.
    Type: Application
    Filed: October 15, 2021
    Publication date: November 16, 2023
    Applicant: The Children's Medical Center Corporation
    Inventors: Talal Chatila, Hani Harb, Mehdi Benamar
  • METHODS AND COMPOSITIONS FOR TREATING CORONAVIRUS INFECTIOUS DISEASE
    Publication number: 20230226095
    Abstract: Described herein are methods and compositions for treating a coronavirus infectious disease, e.g., COVID-19. Aspects of the invention relate to administering to a subject an agent that targets Notch4.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 20, 2023
    Applicant: The Children's Medical Center Corporation
    Inventors: Talal Chatila, Hani Harb, Mehdi Benamar
  • METHOD FOR TREATING ASTHMA OR ALLERGIC DISEASE
    Publication number: 20230212274
    Abstract: Described herein are methods and compositions for treating asthma or an allergic disease. Aspects of the invention relate to administering to a subject an agent that targets the Wnt or Hippo Signaling pathway, or Growth-differentiation factor 15 (GDF15), either alone or in combination. In certain embodiments, the subject is further administered a Notch4 inhibitor.
    Type: Application
    Filed: February 16, 2021
    Publication date: July 6, 2023
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal Amine Chatila, Hani Harb
  • METHODS AND COMPOSITIONS FOR TREATING ASTHMA
    Publication number: 20220033489
    Abstract: Described herein are methods and compositions for treating asthma. Aspects of the invention relates to administering to a subject an agent that inhibits IL-6 signaling. Another aspect of the invention relates to administering the anti-IL-6R antibody, tocilizumab, to a subject in need thereof.
    Type: Application
    Filed: December 4, 2019
    Publication date: February 3, 2022
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal Amine CHATILA, Hani HARB, Brittany ESTY, Wanda PHIPATANAKUL, Lisa M. BARTNIKAS
  • METHOD FOR TREATING ASTHMA OR ALLERGIC DISEASE
    Publication number: 20210278418
    Abstract: Described herein are methods and compositions for treating asthma or an allergic disease. Aspects of the invention relate to administering to a subject an agent that targets Notch4. In one embodiment, the agent is an anti-Notch4 antibody.
    Type: Application
    Filed: March 15, 2019
    Publication date: September 9, 2021
    Applicant: THE CHIDLREN'S MEDICAL CENTER CORPORATION
    Inventors: Talal Amine CHATILA, Hani HARB, Mingcan XIA, Amir MASSOUD