Patents by Inventor Hanna Ben-Artzi

Hanna Ben-Artzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
    Patent number: 6475763
    Abstract: Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: November 5, 2002
    Assignee: Insight Strategy & Marketing Ltd.
    Inventors: Maty Ayal-Hershkovitz, Haim Moskowitz, Daphna Miron, Ayelet Gilboa, Madlene Mimon, Hanna Ben-Artzi, Oron Yacoby-Zeevi, Iris Pecker, Yoav Peleg, Yinon Shlomi
  • Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same
    Patent number: 6348344
    Abstract: Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: February 19, 2002
    Assignee: Insight Strategy & Marketing Ltd.
    Inventors: Maty Ayal-Hershkovitz, Haim Moskowitz, Daphna Miron, Ayelet Gilboa, Madelene Mimon, Hanna Ben-Artzi, Oron Yacoby-Zeevi, Iris Pecker, Yoav Peleg, Yinon Schlomi
  • Method of screening for potential anti-metastatic and anti-inflammatory agents using mammalian heparanase as a probe
    Patent number: 6190875
    Abstract: Qualitative and quantitative methods of testing an agent for its potential at inhibiting glycosidase catalytic activity, the methods including the steps of interacting a glycosidase enzyme with a glycosidase substrate in a presence of the agent and qualitatively or quantitatively evaluating an effect of the agent on the catalytic activity of the glycosidase enzyme toward the glycosidase substrate. Preferably the glycosidase enzyme is a heparanase enzyme and the glycosidase substrate is, respectively, a heparanase substrate.
    Type: Grant
    Filed: July 10, 1998
    Date of Patent: February 20, 2001
    Assignees: Insight Strategy & Marketing Ltd., Hadasit Medical Research & Development Ltd.
    Inventors: Hanna Ben-Artzi, Maty Ayal-Hershkovitz, Israel Vlodavsky, Iris Pecker, Yoav Peleg, Daphna Miron