Patents by Inventor Hannah Farkas-Himsley

Hannah Farkas-Himsley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7560426
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: July 14, 2009
    Assignees: HSC Research and Development Limited Partnership, Ontario Cancer Institute
    Inventors: Clifford A. Lingwood, Ruth Geva, legal representative, Leorah Kroyanker, legal representative, Richard Hill, Hannah Farkas-Himsley
  • Publication number: 20070160535
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Application
    Filed: March 12, 2007
    Publication date: July 12, 2007
    Inventors: Clifford Lingwood, Hannah Farkas-Himsley, Ruth Geva, Leorah Kroyanker, Richard Hill
  • Patent number: 7208468
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: April 24, 2007
    Assignees: HSC Research and Development Limited Partnership, Ontario Cancer Institute
    Inventors: Clifford A. Lingwood, Ruth Geva, legal representative, Leorah Kroyanker, legal representative, Richard Hill, Hannah Farkas-Himsley, deceased
  • Publication number: 20050130895
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Application
    Filed: November 12, 2004
    Publication date: June 16, 2005
    Inventors: Clifford Lingwood, Hannah Farkas-Himsley, Ruth Geva, Leorah Kroyanker, Richard Hill
  • Patent number: 6835710
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: December 28, 2004
    Assignees: HSC Research & Development Limited Partnership, Ontario Cancer Institute
    Inventors: Clifford A. Lingwood, Hannah Farkas-Himsley, Richard Hill
  • Patent number: 6228370
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1, have been found to be useful in the treatment of mammalian neoplasia, particularly, ovarian cancer and skin cancer. Surprisingly, although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: May 8, 2001
    Inventors: Clifford A. Lingwood, Hannah Farkas-Himsley, Richard Hill
  • Patent number: 5968894
    Abstract: Pharmaceutical compositions comprising known verotoxins, particularly, verotoxin 1 and their pentameric subunit B, have been found to be useful in the treatment of mammalian neoplasia, particularly, brain cancer, ovarian cancer, breast cancer and skin cancer. Although verotoxin 1 has previously been shown to have anti-neoplastic activity in vitro, non-lethal doses of verotoxin 1 have been shown to be therapeutically anti-neoplastic in vivo. Use of a sensitizer, such as sodium butyrate, enhances the efficacy of verotoxins and their subunit B.
    Type: Grant
    Filed: November 28, 1995
    Date of Patent: October 19, 1999
    Inventors: Clifford A. Lingwood, Richard Hill, Hannah Farkas-Himsley, deceased, Ruth Geva, Leorah Kroyanker
  • Patent number: 4861754
    Abstract: It has been found that bacteriocins are able to kill virally-infected mammalian cells, including virally infected white blood cells. Accordingly, viral infections can be detected and ultimately treated using the bacteriocins and the methods described herein. The invention is particularly suited to detection and treatment of AIDS infection and infectious mononucleosis infection.
    Type: Grant
    Filed: May 26, 1987
    Date of Patent: August 29, 1989
    Inventor: Hannah Farkas-Himsley