Patents by Inventor Hannah Fiji

Hannah Fiji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzoxazolinone compounds with selective activity in voltage-gated sodium channels
    Patent number: 9273040
    Abstract: Disclosed are compounds of Formula (A) or a salt thereof, wherein “Het”, Ra, and Rb are defined herein, which have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (A) or their salts, and methods of treating neuropathic pain disorders using the same.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: March 1, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Mark E. Layton, Joseph E. Pero, Hannah Fiji, Michael J. Kelly, III, Pablo de Leon, Michael A. Rossi, Kevin F. Gilbert, Anthony J. Roecker, Zhijian Zhao, Swati I P. Mercer, Scott Wolkenberg, James Mulhearn, Lianyun Zhao, Dansu Li
  • Nanodrug targeting protein geranylgeranylation
    Patent number: 9125821
    Abstract: The present invention relates, for example, to a liposome, which can be a basic liposome, a transferrin-conjugated liposome, or a pH-sensitive liposome, which encapsulates a compound that specifically inhibits the activity of a protein prenyltransferase, such as a RabGGTase and/or a GGTase I. The liposomes can be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Grant
    Filed: July 30, 2014
    Date of Patent: September 8, 2015
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, NOF CORPORATION
    Inventors: Fuyuhiko Tamanoi, Jie Lu, Kohei Yoshimura, Ohyun Kwon, Hannah Fiji, Masaru Watanabe
  • NANODRUG TARGETING PROTEIN GERANYLGERANYLATION
    Publication number: 20140341979
    Abstract: The present invention relates, for example, to a liposome, which can be a basic liposome, a transferrin-conjugated liposome, or a pH-sensitive liposome, which encapsulates a compound that specifically inhibits the activity of a protein prenyltransferase, such as a RabGGTase and/or a GGTase I. The liposomes can be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Application
    Filed: July 30, 2014
    Publication date: November 20, 2014
    Inventors: Fuyuhiko Tamanoi, Jie Lu, Kohei Yoshimura, Ohyun Kwon, Hannah Fiji, Masaru Watanabe
  • BENZOXAZOLINONE COMPOUNDS WITH SELECTIVE ACTIVITY IN VOLTAGE-GATED SODIUM CHANNELS
    Publication number: 20140303143
    Abstract: Disclosed are compounds of Formula (A) or a salt thereof, wherein “Het”, Ra, and Rb are defined herein, which have properties for blocking Nav 1.7 ion channels found in peripheral and sympathetic neurons. Also described are pharmaceutical formulations comprising the compounds of Formula (A) or their salts, and methods of treating neuropathic pain disorders using the same.
    Type: Application
    Filed: October 26, 2012
    Publication date: October 9, 2014
    Inventors: Mark E. Layton, Joseph E. Pero, Hannah Fiji, Michael J. Kelly, III, Pablo de Leon, Michael A. Rossi, Kevin F. Gilbert, Anthony J. Roecker, Zhijian Zhao, Swati I P. Mercer, Scott Wolkenberg, James Mulhearn, Lianyun Zhao, Dansu Li
  • Inhibitors of protein prenyltransferases
    Patent number: 8815935
    Abstract: The present invention is directed to novel compounds. These compounds can be useful in inhibiting the activity of protein prenyltransferases including GGTase I and/or RabGGTase. The compounds can also be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: August 26, 2014
    Assignee: The Regents of the University of California
    Inventors: Ohyun Kwon, Fuyuhiko Tamanoi, Hannah Fiji, Masaru Watanabe
  • INHIBITORS OF PROTEIN PRENYLTRANSFERASES
    Publication number: 20130102639
    Abstract: The present invention is directed to novel compounds. These compounds can be useful in inhibiting the activity of protein prenyltransferases including GGTase I and/or RabGGTase. The compounds can also be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Application
    Filed: September 13, 2012
    Publication date: April 25, 2013
    Applicant: The Regents of the University of California
    Inventors: Ohyun Kwon, Fuyuhiko Tamanoi, Hannah Fiji, Masaru Watanabe
  • Inhibitors of protein prenyltransferases
    Patent number: 8093274
    Abstract: The present invention is directed to novel compounds. These compounds can be useful in inhibiting the activity of GGTase I. The compounds can also be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: January 10, 2012
    Assignee: The Regents of the University of California
    Inventors: Fuyuhiko Tamanoi, Ohyun Kwon, Masaru Watanabe, Hannah Fiji
  • INHIBITORS OF PROTEIN PRENYLTRANSFERASES
    Publication number: 20100063114
    Abstract: The present invention is directed to novel compounds. These compounds can be useful in inhibiting the activity of GGTase I. The compounds can also be used as anti-cancer therapeutics including as part of methods for treating cancer, in assays, and in kits.
    Type: Application
    Filed: March 22, 2007
    Publication date: March 11, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Fuyuhiko Tamanoi, Ohyun Kwon, Masaru Watanabe, Hannah Fiji