Abstract: Diagnostic devices for quantitative or qualitative analysis of a sample fluid including an analyte include at least two portions made from a hydrophilic material. The planar portions are stacked on each other and each occupy a different and substantially parallel plane to form a three-dimensional structure. At least one of the planar portions includes a hydrophobic region formed by applying a low surface energy material that extends through a thickness of the substrate portion from a first major surface to a second major surface thereof. The hydrophilic regions in the overlying substantially parallel substrate portions can be aligned with each other such that a fluid is passively transported between adjacent hydrophilic regions to provide a sample flow path between adjacent substrate portions.

Abstract: A diagnostic device includes a sensor stack with multiple panels of a porous material disposed in planes parallel to one another and in face-to-face contact with each other. At least a portion of the panels of the porous material include hydrophobic regions and hydrophilic regions configured to provide a sample flow path for migration of a fluid sample through the sensor stack from one panel to another in the hydrophilic regions. A wicking layer is on a major surface of the sensor stack.

Abstract: Diagnostic devices for quantitative or qualitative analysis of a sample fluid including an analyte include at least two portions made from a hydrophilic material. The planar portions are stacked on each other and each occupy a different and substantially parallel plane to form a three-dimensional structure. At least one of the planar portions includes a hydrophobic region formed by applying a low surface energy material that extends through a thickness of the substrate portion from a first major surface to a second major surface thereof. The hydrophilic regions in the overlying substantially parallel substrate portions can be aligned with each other such that a fluid is passively transported between adjacent hydrophilic regions to provide a sample flow path between adjacent substrate portions.