Patents by Inventor Hannah L. POWERS

Hannah L. POWERS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF
    Publication number: 20240246939
    Abstract: Provided herein are compounds of formula (I?): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein Y2, Y3, L1, L2, X1, X2, X3, X4, X5, Q1, R1, R2, Rk, Rm, and Rn are as defined elsewhere herein. Also provided herein are methods of preparing compounds of formula (I?). Also provided herein are methods of inhibiting GYS1 and methods of treating a GYS1-mediated disease, disorder, or condition in an individual in need thereof.
    Type: Application
    Filed: September 8, 2023
    Publication date: July 25, 2024
    Inventors: David John MORGANS, JR., Kevin MELLEM, Hannah L. POWERS, Patrick Sang Tae LEE, Walter WON, Christopher Joseph SINZ
  • INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF
    Publication number: 20230104740
    Abstract: Provided herein are compounds of formula (I?): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein Y2, Y3, L1, L2, X1, X2, X3, X4, X5, Q1, R1, R2, Rk, Rm, and Rn are as defined elsewhere herein. Also provided herein are methods of preparing compounds of formula (I?). Also provided herein are methods of inhibiting GYS1 and methods of treating a GYS1-mediated disease, disorder, or condition in an individual in need thereof.
    Type: Application
    Filed: March 14, 2022
    Publication date: April 6, 2023
    Inventors: David John MORGANS, JR., Kevin MELLEM, Hannah L. POWERS, Patrick Sang Tae LEE, Walter WON, Christopher Joseph SINZ