Abstract: A bait is provided, wherein the bait comprises a first portion capable of binding to a nucleic acid in a sequence-independent manner, and a second portion capable of binding to a non-silica capture substrate. Compositions comprising such a bait and methods for using such a bait are also disclosed.

Abstract: A method and apparatus for removing magnetic beads together with molecular targets of interest from a fluid is described. A consumable bead collection probe is placed in a vessel containing magnetic beads suspended in the fluid. A magnet outside the vessel concentrates magnetic beads on a surface of the collection probe so they may be manipulated in and out of vessels during washing or processing steps without transferring the fluid into or out of a vessel. In a further embodiment, a vibrational source is attached to the collection probe such that, in combination with the magnet in a position external to the vessel, beads may be washed without releasing them from the collection probe.

Abstract: A bait is provided, wherein the bait comprises a first portion capable of binding to a nucleic acid in a sequence-independent manner, and a second portion capable of binding to a non-silica capture substrate. Compositions comprising such a bait and methods for using such a bait are also disclosed.

Abstract: A method and apparatus for removing magnetic beads together with molecular targets of interest from a fluid is described. A consumable bead collection probe is placed in a vessel containing magnetic beads suspended in the fluid. A magnet outside the vessel concentrates magnetic beads on a surface of the collection probe so they may be manipulated in and out of vessels during washing or processing steps without transferring the fluid into or out of a vessel. In a further embodiment, a vibrational source is attached to the collection probe such that, in combination with the magnet in a position external to the vessel, beads may be washed without releasing them from the collection probe.

Abstract: The present disclosure provides a retractor including an enclosure extending from a first open end to a second open end to form a lumen extending along an axis therebetween and that is accessible from the first open end and the second open end. The retractor further includes a first aperture formed at first angular position in the enclosure, and a second aperture formed at second angular position in the enclosure and opposing the first aperture to form a passage extending transverse to the axis from the first aperture, through the lumen, and to the second aperture. The first aperture and the second aperture are located proximate to the first open end and sized to arrange the passage along a spine of a patient to receive a trocar for delivering a graft material to the spine.

Abstract: The present disclosure provides a retractor including an enclosure extending from a first open end to a second open end to form a lumen extending along an axis therebetween and that is accessible from the first open end and the second open end. The retractor further includes a first aperture formed at first angular position in the enclosure, and a second aperture formed at second angular position in the enclosure and opposing the first aperture to form a passage extending transverse to the axis from the first aperture, through the lumen, and to the second aperture. The first aperture and the second aperture are located proximate to the first open end and sized to arrange the passage along a spine of a patient to receive a trocar for delivering a graft material to the spine.