Abstract: The present invention relates to an optical flow cell (1) for a measuring device, having an input light guide with a light exit surface, an output light guide with a light entrance surface, said input light guide and output light guide being integrated with a holder (30) to form optical flow cell (1), and wherein the holder (30) extends along a first axis (A) and has a through hole (31) for receiving a flow of a sample fluid, said through hole (31) being transversal to said first axis (A), and the input light guide and output light guide further are arranged in said holder (30) so that the light exit surface and the light entrance surface extend into said through hole (31) and are arranged to be in optical alignment with each other and at a first distance from each other. The invention also relates to a measuring device having at least one optical flow cell (1).

Abstract: Disclosed is apparatus (1) for measuring fluorescence and absorbance of a substance in a sample, said apparatus (1) comprising: a flow cell (2) for containing a sample, a first light source (3), a first conductor (5) for transmitting light from the first light source (3) to the flow cell (2) for irradiating a sample contained therein, a second conductor (7) for transmitting light from the flow cell (2) to a sample detector (9) arranged to detect an electromagnetic radiation that has passed through said cell (2), and a processing unit (16) arranged to receive a first signal (31) from a reference detector (15) and a second signal (32) from the sample detector (9) and to determine an absorbance based on said first and second signals (31,32), said apparatus (1) further comprising a second light source (4), a third conductor (6) for transmitting light from the second light source (4) to the cell (2) and wherein the sample detector (9) is further arranged to also detect fluorescence signals in the light that has pa

Abstract: Disclosed is an optical fiber arrangement for inducing coupling among propagation modes of light, said arrangement comprising a multimode optical fiber (30) having an input end (32) for receiving light and an output end (31) for emitting light, with a coupling inducing section (33) extending from said input end to said output end, and a holder (80) on which the optical fiber is arranged, wherein said multimode optical fiber has a non-circular cross section. Disclosed also is a system for measuring the absorption or determining the concentration of a substance, said system comprising at least one optical fiber arrangement.

Abstract: An attachment arrangement for providing a sensor in a flexible bag, said attachment arrangement comprising: a sensor holding part adapted to be integrated with the flexible bag and comprising first locking part protruding out form the flexible bag, the sensor holding part holding an optical sensor inside the flexible bag; an adaptor part provided outside the flexible bag and adapted to hold an optical fiber, the adaptor part comprising second locking part adapted to mate with the first locking part to lock the first locking part and the second locking part together such that the optical fiber can communicate with the optical sensor inside the bag.

Abstract: The present invention relates to a flow cell (10) comprising a fluid inlet (16) and a fluid outlet (18) separated by a sample flow-through chamber (12) comprising at least one UV-transparent window (22?), wherein the at least one UV-transparent window (22?) is made of a polymer material and has been subjected to Gamma radiation sterilisation. In one aspect, the flow cell is combustible.

Abstract: The present invention relates to a flow cell (10) comprising a fluid inlet (16) and a fluid outlet (18) separated by a sample flow-through chamber (12) comprising at least one UV-transparent window (22?), wherein the at least one UV-transparent window (22?) is made of a polymer material and has been subjected to Gamma radiation sterilization. In one aspect, the flow cell is combustible.

Abstract: Disclosed is an apparatus for measuring the absorbance of a substance in a solution, comprising: i) a sample cell (30) of known path length (b) for containing said solution (S), said cell being transparent to light of a predefined wavelength spectrum; ii) plural LED's each being independently operable by means of a controller (25) each for emitting light, within said predefined wavelength spectrum, along a light path; iii) a band pass filter (22) in the light path; iv) a beam splitter (24) for dividing light from said source propagating along the path into a first portion and a second portion, said first portion being directable by the beam splitter toward a reference detector (42) and said second portion being directable into the cell (30); v) a reference detector (42) for detecting the intensity of said first portion of light directed by said beam splitter; and vi) a sample detector (40) for detecting the intensity of the second portion propagating from the cell; the apparatus allowing a sample in the cell

Abstract: Disclosed is an apparatus for measuring the absorbance of a substance in a solution, comprising: i) a sample cell (30) of known path length (b) for containing said solution (S), said cell being transparent to light of a predefined wavelength spectrum; ii) plural LED's each being independently operable by means of a controller (25) each for emitting light, within said predefined wavelength spectrum, along a light path; iii) a band pass filter (22) in the light path; iv) a beam splitter (24) for dividing light from said source propagating along the path into a first portion and a second portion, said first portion being directable by the beam splitter toward a reference detector (42) and said second portion being directable into the cell (30); v) a reference detector (42) for detecting the intensity of said first portion of light directed by said beam splitter; and vi) a sample detector (40) for detecting the intensity of the second portion propagating from the cell; the apparatus allowing a sample in the cell

Abstract: This invention provides a system for operating RFID tags on a single-use connector. The system includes: a first single-use connector configured to receive a first RFID tag and a second single-use connector configured to receive a second RFID tag. The invention also includes a reader placed close to the first RFID tag and the second RFID tag. The reader is configured to: determine if the first RFID tag and the second RFID tag are gamma sterilized; determine if the first RFID tag and the second RFID tag were previously used; determine if the first RFID tag and the second RFID tag are authentic; and determine if the first RFID tag matches with the second RFID tag.

Abstract: The present invention relates to a flow cell (10) comprising a fluid inlet (16) and a fluid outlet (18) separated by a sample flow-through chamber (12) comprising at least one UV-transparent window (22?), wherein the at least one UV-transparent window (22?) is made of a polymer material and has been subjected to Gamma radiation sterilisation. In one aspect, the flow cell is combustible.

Abstract: An attachment arrangement for providing a sensor in a flexible bag, said attachment arrangement comprising: a sensor holding part adapted to be integrated with the flexible bag and comprising first locking means protruding out form the flexible bag, said sensor holding part holding an optical sensor inside the flexible bag; an adaptor part provided outside the flexible bag and adapted to hold an optical fibre, said adaptor part comprising second locking means adapted to mate with said first locking means to lock the two parts together such that the optical fibre can communicate with the optical sensor inside the bag.

Abstract: A method for determining the concentration of a chromatographic medium in a liquid slurry comprises the steps of: providing a column (1) having a top end (3) and a bottom end (2) and adapted to retain a chromatographic medium therein; introducing a defined volume of the slurry (15) into the column (1); providing a liquid flow through the column (1) from the top end to the bottom end of the column to settle the chromatographic medium in the column; measuring the bed height of the consolidated chromatographic medium or a value related thereto; and determining from the measured bed height or value related thereto the concentration, or a value related to the concentration of the chromatographic medium in the slurry. A device for performing the method as well as the use of the method in packing of especially large scale columns are also disclosed.

Abstract: This invention provides a system for operating RFID tags on a single-use connector. The system includes: a first single-use connector configured to receive a first RFID tag and a second single-use connector configured to receive a second RFID tag. The invention also includes a reader placed close to the first RFID tag and the second RFID tag. The reader is configured to: determine if the first RFID tag and the second RFID tag are gamma sterilized; determine if the first RFID tag and the second RFID tag were previously used; determine if the first RFID tag and the second RFID tag are authentic; and determine if the first RFID tag matches with the second RFID tag.

Abstract: The invention relates to a flow cell for an ultrasonic flow meter comprising two transducers of ultrasonic waves wherein the two transducers are reversibly detachable from the flow cell. The flow cell with the transducers detached is sterilisable and is particularly suitable for use in disposable or single-use systems.

Abstract: A method for determining the concentration of a chromatographic medium in a liquid slurry comprises the steps of: providing a column (1) having a top end (3) and a bottom end (2) and adapted to retain a chromatographic medium therein; introducing a defined volume of the slurry (15) into the column (1); providing a liquid flow through the column (1) from the top end to the bottom end of the column to settle the chromatographic medium in the column; measuring the bed height of the consolidated chromatographic medium or a value related thereto; and determining from the measured bed height or value related thereto the concentration, or a value related to the concentration of the chromatographic medium in the slurry. A device for performing the method as well as the use of the method in packing of especially large scale columns are also disclosed.

Abstract: A liquid dispensing apparatus comprises a liquid reservoir (32), an outlet port (6; 36) and driving means for forcing liquid (4) through the outlet port (6, 36). The driving means generates a pulse of gas which impinges upon the liquid (4) in the reservoir (32) so as to force liquid (4) through the outlet port (6, 36). Also disclosed is a cassette comprising a plurality of cartridges for dispensing liquid therefrom. Each cartridge comprises a liquid reservoir (32) and an outlet member (36) mounted so as to close an opening (34) in the liquid reservoir (32). The outlet member (36) provides an outlet port through which the liquid can be forced by a pulse of pressurised gas.

Abstract: The present invention relates to a flow cell (10) comprising a fluid inlet (16) and a fluid outlet (18) separated by a sample flow-through chamber (12) comprising at least one UV-transparent window (22?), wherein the at least one UV-transparent window (22?) is made of a polymer material and has been subjected to Gamma radiation sterilisation. In one aspect, the flow cell is combustible.

Abstract: The invention relates to a flow cell for an ultrasonic flow meter comprising two transducers of ultrasonic waves wherein the two transducers are reversibly detachable from the flow cell. The flow cell with the transducers detached is sterilisable and is particularly suitable for use in disposable or single-use systems.