Patents by Inventor Hanno M. Roder

Hanno M. Roder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-carbacycle monosubstituted indolocarbazoles as protein kinase inhibitors
    Patent number: 7262215
    Abstract: This invention relates to N-carbacycle monosubstituted indolocarbazole compounds. Furthermore, this invention relates to medicaments comprising N-carbacycle monosubstituted indolocarbazoles compounds and the use of such compounds for treating non-insulin dependent diabetes mellitus, acute stroke and other neurotraumatic injuries, for treating diabetes mellitus, as a chemotherapeutic for the treatment of various malignant diseases, for treating diseases caused by malfunctioning of specific signaling pathways, and for treating neurodegenerative diseases such as for example Alzheimer's disease.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: August 28, 2007
    Assignee: NAD AG
    Inventors: Heidi Sahagun-Krause, Olivier Thillaye Du Boullay, Valerie Thillaye Du Boullay, Laura Casiraghi, Hans-Wolfgang Klafki, Pierfausto Seneci, Tobias Braxmeier, Silvia Müller, Wolfgang Fr{hacek over (o)}hner, Barbara Monse, Sandra Gordon, Hanno M. Roder
  • NOVEL TAU/NEUROFILAMENT PROTEIN KINASES
    Publication number: 20020025942
    Abstract: Novel TAU/neurofilament protein kinases, PK40 and PK36, are essentially purified and characterized. Novel immunoassays relating to the kinases and inhibitors for the kinases also are provided. Finally, DNA sequences encoding the kinases and cell lines relating to the kinases are provided.
    Type: Application
    Filed: March 20, 1998
    Publication date: February 28, 2002
    Inventors: VERNON M. INGRAM, HANNO M. RODER
  • Method of inhibiting abnormal tau hyper phosphorylation in a cell
    Patent number: 5955444
    Abstract: Novel TAU/neurofilament protein kinases, PK40 and PK36, are essentially purified and characterized. Novel immunoassays relating to the kinases and inhibitors for the kinases also are provided. Finally, DNA sequences encoding the kinases and cell lines relating to the kinases are provided. Methods of inhibiting abnormal tau HYPER PHOSPHORYLATION activity in a cell by contacting a cell with an inhibitor that binds to an ATP binding site of PK40, in an amount sufficient to inhibit said phosphorylating activity which is characteristic of abnormal tau HYPERPHOSPHORYLATION in Alzheimer's Disease is also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 21, 1999
    Assignee: Massachusetts Institute of Technology
    Inventors: Vernon M. Ingram, Hanno M. Roder