Patents by Inventor Hanns-Joachim Weinmann

Hanns-Joachim Weinmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic metal complexes and their use for the production of conjugates with biomolecules
    Publication number: 20070009442
    Abstract: The invention relates to macrocyclic metal complexes and their production and use for the production of conjugates with biomolecules. The conjugates are suitable as contrast media in NMR diagnosis and radiodiagnosis as well as for radiotherapy. High relaxivity is achieved by a special liganding of macrocyclic compounds, and a fine-tuning of the relaxivity is made possible.
    Type: Application
    Filed: March 28, 2006
    Publication date: January 11, 2007
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Gunther Michl, Thomas Frenzel, Detlev Sulzle, Hans Bauer, Bernd Raduchel, Hanns-Joachim Weinmann, Heiko Schirmer
  • Metal complex-containing pharmaceutical agents
    Publication number: 20060165591
    Abstract: Improved metal complex-containing pharmaceutical agents are described which, as an additive, contain one or more complexing agents and/or one or more weak metal complex(es) or mixtures thereof.
    Type: Application
    Filed: March 23, 2006
    Publication date: July 27, 2006
    Inventors: Heinz Gries, Ulrich Speck, Hanns-Joachim Weinmann, Hans Niendorf, Wolfgang Seifert
  • Trimeric, macrocyclically substituted halo-benzene derivatives
    Publication number: 20060154989
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine, and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Application
    Filed: November 14, 2005
    Publication date: July 13, 2006
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Jose Luis Martin, Juan Harto
  • DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production
    Patent number: 7074387
    Abstract: Compounds of formula I wherein Z1, Z2, X, R2 and R3 are as defined herein, are suitable as NMR shift reagents.
    Type: Grant
    Filed: March 25, 2003
    Date of Patent: July 11, 2006
    Assignee: Schering AG
    Inventors: Heinz Gries, Erich Klieger, Bernd Raduechel, Heribert Schmitt-Willich, Hanns-Joachim Weinmann, Hubert Vogler, Gabriele Schuhmann-Giampieri, Juergen Conrad
  • Trimeric, macrocyclically substituted aminoisophthalic acid-halo-benzene derivatives
    Publication number: 20060120965
    Abstract: The metal complexes of general formula I in which Hal stands for bromine or iodine, and A1 and A2 have different meanings, are suitable as contrast media.
    Type: Application
    Filed: November 16, 2005
    Publication date: June 8, 2006
    Inventors: Johannes Platzek, Heiko Schirmer, Hanns-Joachim Weinmann, Jose Martin, Juan Harto
  • Galenical formulations
    Publication number: 20060093554
    Abstract: This invention describes new galenical formulations that contain paramagnetic and diamagnetic perfluoroalkyl-containing compounds. The new formulations are suitable as contrast media for nuclear spin tomography.
    Type: Application
    Filed: September 12, 2005
    Publication date: May 4, 2006
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Raduechel, Peter Mareski, Bernd Misselwitz, Thomas Frenzel, Hanns-Joachim Weinmann
  • 1,4,7,10-Tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
    Publication number: 20060078503
    Abstract: 1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA in which R1 means hydrogen or a metal ion equivalent independent of one another and R2 means a butyltriol radical as well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
    Type: Application
    Filed: September 26, 2005
    Publication date: April 13, 2006
    Inventors: Johannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rudiger Press
  • 1,4,7,10-tetraazacyclododecane butyltriols, processes for their production and pharmaceutical agents containing them
    Patent number: 6951639
    Abstract: 1,4,7,10-Tetraazacyclodedecane butyltriols of general formula IA in which R1 means hydrogen or a metal ion equivalent independent of one another and R2 means a butyltriol radical as well as their salts with organic or inorganic bases or amino acids are valuable pharmaceutical agents.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: October 4, 2005
    Assignee: Schering AG
    Inventors: Johannes Platzek, Heinz Gries, Hanns-Joachim Weinmann, Gabriele Schuhmann-Giampieri, Wolf-Rüdiger Press
  • Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis
    Patent number: 6916461
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy. The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: July 12, 2005
    Assignee: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Radüchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis
    Publication number: 20050147563
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy. The compounds according to the invention are suitable especially as in vivo contrast media in nuclear spin tomography (MRT). They can preferably be used as blood-pool agents and as lymphographic agents.
    Type: Application
    Filed: October 5, 2004
    Publication date: July 7, 2005
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Raduchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Publication number: 20050118105
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Application
    Filed: September 30, 2004
    Publication date: June 2, 2005
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
    Publication number: 20050074409
    Abstract: The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration<10?3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R1)>10 I/mmol.s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.
    Type: Application
    Filed: June 2, 2004
    Publication date: April 7, 2005
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Patent number: 6855309
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: February 15, 2005
    Assignee: Schering, AG
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Trimeric macrocyclic substituted benzene derivatives
    Publication number: 20040265236
    Abstract: The metal complexes of general formula I 1
    Type: Application
    Filed: February 19, 2004
    Publication date: December 30, 2004
    Inventors: Heiko Schirmer, Hanns-Joachim Weinmann, Johannes Platzek, Jose Luis Martin, Juan R. Harto, Bjoern Riefke
  • Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
    Patent number: 6818203
    Abstract: The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10−3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R1)>10 l/mmol·s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: November 16, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of intravascular thrombi
    Publication number: 20040131546
    Abstract: The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration <10−3 mol/l, a hydrodynamic micelle diameter (2 Rh)>1 nm and a proton relaxivity in plasma (R)>10 l/mmol s as contrast media in MR imaging for visualization of intravascular thrombi.
    Type: Application
    Filed: July 10, 2003
    Publication date: July 8, 2004
    Applicant: Schering AG
    Inventors: Bernd Misselwitz, Johannes Platzek, Yoko Kawata, Hanns-Joachim Weinmann, Takashi Yokawa, Ulrich Niedballa
  • Perfluoroalkyl-containing complexes with polar radicals, process for their production and their use
    Patent number: 6676928
    Abstract: Perfluoroalkyl-containing complexes with polar radicals of general formula I (K)1-G-(Z-Rf)m(R)p  (I) in which R means the polar radical, Rf means a perfluorinated carbon chain, K is a metal complex, and Z represents a linker group, are suitable for intravenous lymphography, for tumor diagnosis and for infarction and necrosis imaging.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: January 13, 2004
    Assignee: Schering Aktiengesellschaft
    Inventors: Johannes Platzek, Peter Mareski, Ulrich Niedballa, Bernd Raduechel, Hanns-Joachim Weinmann, Bernd Misselwitz
  • Cascade polymer bound complexing compounds, their complexes and conjugates, processes for their production, and pharmaceutical agents containing them
    Publication number: 20030232017
    Abstract: Cascade polymers, containing complex-forming ligands, optionally at least five ions of an element of atomic numbers 21-29, 39, 42, 44 or 57-83, as well as, if desired, cations of inorganic and/or organic bases, amino acids or amino acid amides, are valuable complexing compounds and complexes for diagnostics and therapy.
    Type: Application
    Filed: December 11, 2002
    Publication date: December 18, 2003
    Inventors: Johannes Platzek, Heribert Schmitt-Willich, Heinz Gries, Gabriele Schuhmann-Giampieri, Hubert Vogler, Hanns-Joachim Weinmann, Hans Bauer
  • Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis
    Publication number: 20030232012
    Abstract: The invention relates to new, monomeric, perfluoroalkyl-substituted metal complexes, processes for their production, and their use in diagnosis and therapy.
    Type: Application
    Filed: July 18, 2002
    Publication date: December 18, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Ulrich Niedballa, Bernd Raduchel, Wolfgang Schlecker, Hanns-Joachim Weinmann, Thomas Frenzel, Bernd Misselwitz, Wolfgang Ebert
  • Metal complex-containing pharmaceutical agents
    Publication number: 20030206858
    Abstract: Improved metal complex-containing pharmaceutical agents are described which, as an additive, contain one or more complexing agents and/or one or more weak metal complex(es) or mixtures thereof.
    Type: Application
    Filed: June 16, 2003
    Publication date: November 6, 2003
    Applicant: Schering AG
    Inventors: Heinz Gries, Ulrich Speck, Hanns-Joachim Weinmann, Hans Peter Niendorf, Wolfgang Seifert