Abstract: The present invention relates to complexes which contain polycrystalline magnetic iron oxide particles in a pharmaceutically acceptable shell, and to the use of these compositions in magnetic particle imaging (MPI). Particular preference is given to the use of these compositions in examining the gastrointestinal tract, the vascular system of the heart and cranial components, in the diagnosis of arteriosclerosis, infarctions, and tumors and metastases, for example of the lymphatic system.

Abstract: To increase the contrast in the imaging in an object under examination that contains at least one radiopaque element, an arrangement that has the following features is used: a) at least one essentially polychromatic x-ray radiation source that emits x-ray radiation, b) at least one energy-dispersive detector, with which the intensity of the x-ray radiation that gets through the object under examination is detectable, c) at least one correlation unit, with which the intensity of the detected x-ray radiation from a pixel of the object under examination with a first energy E1 can be correlated with the intensity of the detected x-ray radiation from the same pixel with a second energy E2, d) at least one output unit for visualizing the object under examination from the pixel signals that are obtained by correlation of the intensities.

Abstract: This invention describes the use of metal complexes that have a plasma protein bond of at least 10% as imaging diagnostic agents for locating an infarction or a necrosis using lasting positive visualization.