Abstract: The invention relates to compounds of the formula (I), in which R1, R2, R3, R4, Y and A have the meanings indicated, and to processes for the preparation thereof and to the use thereof for the preparation of medicaments.

Abstract: Process for the preparation of compounds of the formula (I) in which X has the meaning indicated in Patent Claim 1, and precursors thereof.

Abstract: The invention relates to a method for production of compounds of formula (I), where X has the meaning given in claim 1 and precursors for the same.

Abstract: Novel compounds of the formula (I), in which D, W, X, Y, T, m and R1 have the meaning indicated in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

Abstract: The invention relates to compounds of the formula (I), in which R1, R2, R3, R4, Y and A have the meanings indicated, and to processes for the preparation thereof and to the use thereof for the preparation of medicaments.

Abstract: In a device for the temperature control of microcomponents, in particular micro-reactors, which preferably have a plate-shaped design and preferably consist of silicon, at least one microcomponent is pressed against a temperature-control element in a holder. A flat heat-conducting connection exists between the microcomponent and the temperature-control element.

Abstract: In a method for the taking and analysis of samples from a microreaction system (3) having a suction line (9) arranged laterally alongside a discharge aperture (4) of the microreaction system (3), a reduced pressure is generated in the suction line (9) for the aspiration of substances exiting from the discharge aperture (4), causing the exiting substance stream to be divided into an aspirated substance stream and a free-falling substance stream, and one of the two divided substance streams is subsequently fed to an analytical device (10) for analysis. The reduced pressure in the suction line (9) can be influenced and thus the division of the exiting substance stream can be controlled as a function of a result of the analysis. Reaction parameters can also be pre-specified or controlled as a function of analytical results.

Abstract: The present invention relates to processes for the bromination of organic compounds, and to bromination microreactors for carrying out these processes.

Abstract: The invention relates to a sampling device (1) for a microreaction system (3), comprising an outlet (4) and a suction line opening (9) which is arranged next to the outlet (4). A depression can be produced in the suction line (9) for the suction of the substances (13) leaving the outlet (4). The outlet (4) is embodied as a capillary and can be positioned in relation to the opening of the suction line (9). The outlet (4) is surrounded by a housing (6) comprising a discharge outlet (14) for the substances (13) leaving the outlet (4), and a through-opening (8) for the suction line (9). Said suction line (9) opens up into a collecting tank (10) that is connected to a vacuum line (12) by means of an electrovalve (1).

Abstract: The present invention relates to a process for the reduction of aliphatic, aromatic or heterocyclic organic compounds by means of hydrides and/or derivatives thereof.

Abstract: Microwells, which are open on both sides and are arranged two-dimensionally in a microwell matrix (4), are hermetically closed by pressure on both sides using plugs (6) covered with a sealing sheet (11). A layer of elastic material (9), which is arranged between the plug (6) and the sealing sheet (11), guarantees uniform pressure on all the microwells of a microwell matrix (4) which is loosely held by a frame structure (1). Continuous peripheral elevations (2), which protrude in both directions at right angles to the plane of the microwell matrix (4), ensure that the deformable thin layer of elastic material (9) does not escape sideways between the plug (6) and the microwell matrix (4) during the pressing process. A plurality of microwell matrices (4) are held simultaneously by the frame structure (1) and are hermetically closed by a corresponding number of allocated plugs (6), which are fastened to a base plate (7) and a cover plate (8), respectively.

Abstract: The invention relates to a method for production of compounds of formula (I), where X has the meaning given in claim 1 and precursors for the same.

Abstract: The present invention relates to a process for the dehydration of organic compounds to give unsaturated compounds.

Abstract: In a device for connecting microcomponents, in particular microreactors, which preferably have a plate-shaped design and preferably consist of silicon, a sealing plate having apertures which correspond to apertures in the microcomponents is arranged between the microcomponents.

Abstract: Novel compounds of the formula (I), in which D, W, X, Y, T, m and R1 have the meaning indicated in Patent claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumours.

Abstract: The invention relates to a method for the 1,3 dipolar cycloaddition of organic compounds, characterized in that the reaction is carried out in a microreactor.

Abstract: A device for the emulsification and separation of small amounts of immiscible liquid phases has essentially a cover plate (2), which can be tightly connected to a base plate (1), where microchannels (4,4a,5,6,6a) in the form of grooves are cut out on the inner surface (3,3a) of the base plate (1) and/or cover plate (2). In a mixing zone, two microchannels (4,4a) run in a wave shape crossing one another a number of times. In a subsequent separation zone, they run essentially straight combined in a common microchannel (5). The otherwise tightly sealed-off microchannels (4,4a,5,6,6a) can be filled and emptied again via inlet apertures (8,8a) and outlet apertures (9,9a).

Abstract: The present invention relates to a process for the preparation of indoles.

Abstract: An interconnection support for plate-like microcomponents (1) has a support rail (2) which is attached to a support plate (3). An insertion slot (4) for the support rail (2) accommodates an insertion edge (5) of a plate-like microcomponent (1). Like connections (10, 10a), which can be connected to associated connections (11) in an outside (1a) of the plate-like microcomponent (1), are provided in at least one side wall (9) of the insertion slot (4) of the support rail (2).

Abstract: The invention generally relates to a method of formylating organic compounds in a microreactor.