Abstract: An autoclavable multi-layer film formed of thermoplastic materials capable of being processed into hollow shapes and useful for packaging oxygen sensitive materials. The film includes sequential layers A--B--C--D--C--B'--A', wherein the film may optionally not include layer A or A' and the corresponding layer B or B'. A and A' are layers substantially water and water vapor resistant, wherein at least one of the layers A and A' is made of polyolefins, polyethylene terephthalates, or co-polymers of polyethylene terephthalates. B and B' are layers adhesively bonding layers A and A' with layers C. C is a layer of a moisture absorbing polymer substantially impermeable to oxygen. The polymer is selected from the group consisting of aromatic polyamides and co-polymers of aromatic polyamides. D is a layer of a polyethylene-vinyl alcohol with a molar ethylene concentration between 0% and 80%.