Patents by Inventor Hannu Nikander
Hannu Nikander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9949869Abstract: The present invention relates to novel intrauterine systems and to methods for manufacturing these systems. An intrauterine system according to the invention comprises a reservoir and a continuous, closed and flexible frame. The frame comprises a thermoplastic polyurethane elastomer made of a polycarbonate diol, 1,6-hexamethylenediisocyanate, and a chain extender.Type: GrantFiled: September 30, 2010Date of Patent: April 24, 2018Assignee: BAYER OYInventors: Taina Tjäder, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Pirjo Kortesuo, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikäinen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Faisal Shafiq, Wolfgang Kaufhold, Christian Wamprecht
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Publication number: 20170367876Abstract: The present invention relates to novel intrauterine systems and to methods for manufacturing these systems. An intrauterine system according to the invention comprises a reservoir and a continuous, closed and flexible frame.Type: ApplicationFiled: August 1, 2017Publication date: December 28, 2017Inventors: Pirjo Kortesuo, Ulla Calvo-Alonso, Pirjo lnki, Harri Jukarainen, llkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikäinen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjäder, Andrew Macleod, Michael Noble, David Whitaker
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Publication number: 20150051481Abstract: The present invention relates to novel intrauterine systems and to methods for manufacturing these systems. An intrauterine system according to the invention comprises a reservoir and a continuous, closed and flexible frame.Type: ApplicationFiled: October 24, 2013Publication date: February 19, 2015Applicant: Bayer OYInventors: Pirjo KORTESUO, Ulla Calvo-Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikäinen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjäder, Andrew Macleod, Michael Noble, David Whitaker
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Publication number: 20120272969Abstract: The present invention relates to novel intrauterine systems and to methods for manufacturing these systems. An intrauterine system according to the invention comprises a reservoir and a continuous, closed and flexible frame. The frame comprises a thermoplastic polyurethane elastomer made of a polycarbonate diol, 1,6-hexamethylenediisocyanate, and a chain extender.Type: ApplicationFiled: September 30, 2010Publication date: November 1, 2012Applicant: BAYER OYInventors: Taina Tjäder, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Pirjo Kortesuo, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikäinen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Faisal Shafiq, Wolfgang Kaufhold, Christian Wamprecht
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Publication number: 20110056501Abstract: The present invention relates to novel intrauterine systems and to methods for manufacturing these systems. An intrauterine system according to the invention comprises a reservoir and a continuous, closed and flexible frame.Type: ApplicationFiled: April 1, 2009Publication date: March 10, 2011Applicant: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikäinen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjäder, Andrew Macleod, Michael Noble, David Whitaker
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Publication number: 20100285097Abstract: The present invention is related to an intravaginal delivery system for the controlled release of drospirenone and an estrogen, optionally also comprising one or more therapeutically active or a health-promoting substance capable of giving and/or enhancing protection against bacterial and fungal infections, and/or enhancing protection against sexually transmitted diseases. The delivery system consists of one or more compartments, one of each comprising a core and a membrane encasing the core, said core and membrane essentially consisting of a same or different polymer composition, wherein at least one compartment comprises drospirenone ant at least one compartment which may be the same or different from the one comprising drospirenone, comprises an estrogen or a mixture of drospirenone and an estrogen, and wherein the membrane or the surface of the membrane or at least one of the cores comprises said therapeutically active or a health-promoting substance.Type: ApplicationFiled: November 19, 2008Publication date: November 11, 2010Inventors: Christine Talling, Vladimir Hanes, Antti Keinänen, Svante Holmberg, Hannu Nikander
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Publication number: 20090142313Abstract: The present invention is related to an intravaginal delivery system for the controlled release of drospirenone and an estrogen, optionally also comprising one or more therapeutically active or a health-promoting substance capable of giving and/or enhancing protection against bacterial and fungal infections, and/or enhancing protection against sexually transmitted diseases. The delivery system consists of one or more compartments, one of each comprising a core and a membrane encasing the core, said core and membrane essentially consisting of a same or different polymer composition, wherein at least one compartment comprises drospirenone ant at least one compartment which may be the same or different from the one comprising drospirenone, comprises an estrogen or a mixture of drospirenone and an estrogen, and wherein the membrane or the surface of the membrane or at least one of the cores comprises said therapeutically active or a health-promoting substance.Type: ApplicationFiled: November 20, 2008Publication date: June 4, 2009Applicant: Bayer Schering Pharma OyInventors: Christine Talling, Vladimir Hanes, Antti Keinanen, Svante Holmberg, Hannu Nikander
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Publication number: 20040014726Abstract: The present invention is directed to a method for the preparation of a pharmaceutical composition having osteoclast formation inhibiting or suppressing activity, characterized in that, as the active agent, a compound of the formula (I) is used, in which formula Q1 is hydrogen, hydroxyl, halogen, amino —NH2, or —OR′, wherein R′ is C1-C4-alkyl or acyl, Q2 is straight or branched alkyl, hydroxyalkyl or aminoalkyl, or a corresponding unsaturated group optionally substituted at the hydroxy or amino group, or a unsubstituted or substituted, saturated or unsaturated cycloalkyl, which can be bound to the methylene carbon over a straight or branched alkylene group, or is the group (a) wherein Y is a saturated or unsaturated heterocyclic group, or a carbocyclic aromatic group, X is a bond, O, S or NR3, wherein R3 is hydrogen or a protecting group, especially lower alkyl, acyl, aryl or arylalkyl, and n is an integer 0 to 6, R1 and R2 are independently hydrogen or C1-C4-alkyl, or it is halogen, anType: ApplicationFiled: April 25, 2003Publication date: January 22, 2004Inventors: Thua Osterman, Ritva Hannuniemi, Teuvo Hentunen, Sirpa Liukko-Sipi, Hannu Nikander, Katri Selander, Raija Sellman, Kalervo Vaananen
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Patent number: 6083938Abstract: The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisophosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis.Type: GrantFiled: December 23, 1998Date of Patent: July 4, 2000Assignee: Leiras OyInventors: Marjaana Heikkila-Hoikka, Hannu Nikander, Ritva Hannuniemi, Leena Lauren, Terttu Kleimola, Sirpa Liukko-Sipi, Kalervo Vaananen, Raija Sellman
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Patent number: 5866556Abstract: The present invention relates to certain optionally ring substituted pyridinylaminomethylidene bisphosphonic acid tetralkyl esters (I) and their use for the treatment of bone diseases, such as osteolytic bone diseases due to malignancy, Paget's disease and primary and secondary osteoporosis.Type: GrantFiled: December 6, 1996Date of Patent: February 2, 1999Assignee: Leiras OyInventors: Marjaana Heikkila-Hoikka, Hannu Nikander, Ritva Hannuniemi, Leena Lauren, Terttu Kleimola, Sirpa Liukko-Sipi, Kalervo Vaananen, Raija Sellman
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Patent number: 5438048Abstract: Novel pharmacologically active methylenebisphosphonates having formula (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently are straight or branched, optionally unsaturated C.sub.1 -C.sub.10 -alkyl, optionally unsaturated C.sub.3 -C.sub.10 -cycloalkyl, aryl, aralkyl, silyl SiR.sub.3 or hydrogen, whereby in formula (I) at least one of the groups R.sup.1, R.sup.2, R.sup.3 or R.sup.4 is hydrogen and at least one of the groups is different from hydrogen, Q.sup.1 is hydrogen, hydroxyl, halogen, amino NH.sub.2, or OR', wherein R' is C.sub.1 -C.sub.4 -lower alkyl or acyl, Q.sup.2 is straight or branched, optionally unsaturated C.sub.1 -C.sub.10 -alkyl, -hydroxyalkyl or -aminoalkyl, whereby the oxygen may, as a substituent, contain one group or the nitrogen as a substituent may contain one or two groups, which are C.sub.1 -C.sub.4 -lower alkyl or acyl, or the two substituents of the nitrogen form together with the nitrogen atom a saturated, partly saturated or an aromatic heterocyclic ring, or Q.sup.Type: GrantFiled: October 20, 1993Date of Patent: August 1, 1995Assignee: Leiras OyInventors: Hannu Nikander, Marjaana Heikkila-Hoikka, Esko Pohjala, Hannu Hanhijarvi, Leena Lauren
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Patent number: 5393748Abstract: Novel pharmacologically active methylenebisphosphonates having formula (I) wherein R.sup.1 -R.sup.4 independently are C.sub.1 -C.sub.10 -alkyl, C.sub.3 -C.sub.10 -cycloalkyl, aryl, aralkyl, silyl SiR.sub.3 or hydrogen, whereby in formula (I) at least one of the groups R.sup.1 -R.sup.4 is hydrogen and at least one of the groups R.sup.1 -R.sup.4 is different from hydrogen, Q.sup.1 is hydrogen, hydroxyl, halogen, amino NH.sub.2, or OR'.sub.1, wherein R'.sub.1 is C.sub.1 -C.sub.4 -alkyl or acyl, Q.sup.2 is the group (.alpha.) wherein Y is a six-membered heterocyclic group, or a carbocyclic aromatic group, X is a bond, O, S or NR'", wherein R'" is hydrogen, lower alkyl, or acyl, n is the integer 0 to 6, and R' and R" are hydrogen or lower alkyl provided that as a ring atom of the ring Y and/or a chain atom of the group X, there is always at least one heteroatom from the group O, N and S, including the steroisomers and the salts of the compounds.Type: GrantFiled: October 20, 1993Date of Patent: February 28, 1995Assignee: Leiras OyInventors: Esko Pohjala, Marjaana Heikkila-Hoikka, Hannu Nikander, Hannu Hanhijarvi
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Patent number: D603038Type: GrantFiled: October 1, 2008Date of Patent: October 27, 2009Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612926Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612927Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612928Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612929Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612930Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker
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Patent number: D612931Type: GrantFiled: September 11, 2009Date of Patent: March 30, 2010Assignee: Bayer Schering Pharma OyInventors: Pirjo Kortesuo, Ulla Calvo Alonso, Pirjo Inki, Harri Jukarainen, Ilkka Jutila, Juha Lehtinen, Eeva Lukkari-Lax, Heikki Lyytikainen, Joachim Moede, Hannu Nikander, Pirjo Sallinen, Taina Tjader, Andrew MacLeod, Michael Nobel, David Whitaker